Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Edward S. Cole"'
Autor:
Sadollah Abedini, Bengt Fellström, Edward S. Cole, Alan G. Jardine, Patrice M. Ambühl, Winfried März, Bart Maes, Carola Grönhagen-Riska, Ingar Holme, Hans-Hellmut Neumayer, Gisela Weihrauch, Hallvard Holdaas
Publikováno v:
Clinical Journal of the American Society of Nephrology. 4:1246-1254
Renal transplant recipients experience premature cardiovascular disease and death. The association of inflammation, all-cause mortality, and cardiovascular events in renal transplant recipients has not been examined in a large prospective controlled
Autor:
Chyi-Hung Hsu, Andrej Skerjanec, Hans-H. Neumayer, Robert Schmouder, Helio Tedesco, Klemens Budde, Edward S. Cole
Publikováno v:
The Journal of Clinical Pharmacology. 45:1268-1278
The pharmacokinetics, safety, and preliminary efficacy of FTY720, a novel immunomodulator, were examined in de novo renal transplant patients. Both noncompartmental and population methods were used to estimate pharmacokinetic estimates in the patient
Autor:
Matthias Büchler, Paul Keown, Steve Chadban, Edward S. Cole, Eric Thervet, Karsten Midtvedt, Hans Prestele
Publikováno v:
Nephrology Dialysis Transplantation. 21:197-202
Background. Therapeutic drug monitoring for cyclosporine microemulsion (CsA-ME) is often performed using either trough levels (C0) or levels at 2 h post-dose (C2). This analysis assessed changes in C0 and C2 and their relationship to CsA-ME dose over
Autor:
Edward S. Cole, Bengt Fellström, Hans-Hellmut Neumayer, Alan G. Jardine, Anders G. Olsson, Hallvard Holdaas, Søren Madsen, John Logan, Gudrun Nyberg, Carola Grönhagen-Riska, Terje R. Pedersen, Patrice M. Ambühl, Bart Maes
Publikováno v:
American Journal of Kidney Diseases. 46:529-536
Renal transplantation is associated with an increased risk for premature cardiovascular disease. We analyzed the data in the placebo arm of Assessment of Lescol in Renal Transplantation (ALERT) to improve our understanding of the relationship between
Autor:
Bengt Fellstr m, Claudio Gimpelewicz, Carola Gr nhagen-Riska, Hallvard Holdaas, Inga Soveri, Hans H. Neumayer, Bart Maes, Alan G. Jardine, Edward S. Cole
Publikováno v:
Transplantation. 79:1160-1163
Renal-transplant recipients have shortened life expectancy primarily because of premature cardiovascular disease. Traditional and nontraditional risk factors for cardiovascular disease are prevalent in renal patients. In renal-transplant recipients,
Autor:
Josephine Kyazike, Qun Zhou, Tim Edmunds, Elizabeth Higgins, Yann Echelard, Edward S. Cole, Harry M. Meade
Publikováno v:
Journal of Biotechnology. 117:57-72
Glycosylation is involved in the correct folding, targeting, bioactivity and clearance of therapeutic glycoproteins. With the development of transgenic animals as expression systems it is important to understand the impact of different genetic backgr
Autor:
Terje R. Pedersen, Patrice M. Ambühl, Bengt Fellström, Hans-Hellmut Neumayer, Per Fauchald, Gudrun Nyberg, Anders Hartmann, Bart Maes, Anders G. Olsson, Hallvard Holdaas, Ingar Holme, Søren Madsen, Carola Grönhagen-Riska, John Logan, Edward S. Cole, Alan G. Jardine
Publikováno v:
Kidney International. 66:1549-1555
Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial.BackgroundHyperlipidemia is a risk factor for long-term renal transplant dysfunction, but no prospective clinical trials have investigated the eff
Autor:
Lorenzo Toselli, Per Pfeffer, Raymond Dandavino, Steven J. Chadban, Matthias Büchler, L. Pallardó, Maria Scolari, Francesco Paolo Schena, Edward S. Cole, César Agost Carreno, Eric Thervet, Helen Pilmore, John K. Connolly
Publikováno v:
Transplantation. 76:903-908
Background. MO2ART (monitoring of 2-hr absorption in renal transplantation) is the first prospective, multicenter trial of cyclosporine (CsA) blood level 2 hr postdose (C 2 ) monitoring in de novo kidney recipients receiving CsA microemulsion (ME) (N
Autor:
Catherine O'grady, Nava Maham, Daniel C. Cattran, Jayne Hamel, Edward S. Cole, Stanley S. A. Fenton, Robert B. Smith, Carl J. Cardella
Publikováno v:
Transplantation. 75:2086-2090
BACKGROUND Cyclosporine monitoring using the 2-hr postdose sample, C2, has been shown to have advantages in monitoring de novo renal transplant recipients. The purpose of this study was to assess cyclosporine exposure, using C2, in stable renal trans
Publikováno v:
Transplantation. 73:S19-S22