Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Edward Reich"'
Autor:
Edward Reich, Branko Brdar
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:1481-1492
We have shown that 5-bromotubercidin (BrTu), a cytotoxic pyrrolo[2, 3-d]pyrimidine analogue of adenosine can be used as a metabolic probe which possesses biological specificity and selectivity: 1) BrTu entered mammalian cell nucleotide pool by phosph
Autor:
Edward Reich, Branko Brdar
Publikováno v:
Journal of Virology. 73:6444-6452
We describe the selective irreversible inhibition of mengovirus growth in cultured cells by a combination of two pyrrolopyrimidine nucleoside analogues, 5-bromotubercidin (BrTu) and tubercidin (Tu). At a concentration of 5 μg/ml, BrTu reversibly blo
Publikováno v:
Mutation research. 609(1)
Protein synthesis elongation factor 2 (EF-2) from eukaryotes contains a conserved post-translationally modified histidine residue known as diphthamide. Diphthamide is a unique site of ADP-ribosylation by diphtheria toxin (DT), which is responsible fo
Publikováno v:
Croatian medical journal. 43(5)
To assess the ability of human immunodeficiency virus-1 (HIV-1) tat- and tat/nef-defective genomes containing diphtheria toxin A chain gene (DTA) to inhibit replication of HIV in human cells.Plasmids were constructed to contain the HIV-1 genome disab
Publikováno v:
The Journal of Laryngology & Otology. 109:770-771
Paralysis of the tongue due to isolated bilateral hypoglossal nerve palsy is a rare occurrence. Due to a trauma the cause in our case may have been a traction injury to both hypoglossal nerves at the base of skull. In some cases a contributing factor
Publikováno v:
The Journal of Experimental Medicine
Cultured thioglycollate-stimulated peritoneal macrophages synthesize, accumulate, and continuously release high levels of plasminogen activators for at least 4 days whereas cultures of unstimulated macrophages do not; the higher specific catalytic ac
Publikováno v:
Cell. 13:475-486
With the exception of certain blood cells considered in the accompanying paper (Valinsky, Easton and Reich, 1978), merocyanine 540 (MC 540), a fluorescent membrane probe, selectively strains the membranes of a wide variety of electrically excitable c
Publikováno v:
Journal of Biological Chemistry. 258:14106-14115
We report the isolation of a specific protease zymogen from chicken plasma. The purification procedure involves barium citrate precipitation, ammonium sulfate fractionation, removal of plasminogen and plasmin on lysine-Sepharose, followed by anion an
Publikováno v:
Cell. 15:1301-1312
To explore the generality of the effects of sarcoma viruses, tumor-promoting phorbol esters and retinoic acid, we have studied plasminogen activator production in differentiating chick myogenic cultures. Although slightly higher than in chick fibrobl
Publikováno v:
Journal of Biological Chemistry. 249:4295-4305
The cell factor that is involved in tumor-associated fibrinolysis has been partially purified from the supernatant fluid of transformed chicken embryo fibroblast cultures. It is an arginine-specific protease that acts as a plasminogen activator. The