Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Edward R. Duncan"'
Autor:
Alexander Carpenter, Laura M. K. Pannell, Syed I. A. Rizvi, Kirsty Maciver, Cha Rajakaruna, Franco Ciulli, Edward R. Duncan, Glyn Thomas, Palash Barman, Richard Bond, Ashley M. Nisbet
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2024)
BackgroundEfforts to maintain sinus rhythm in patients with persistent atrial fibrillation (PsAF) remain challenging, with suboptimal long-term outcomes.MethodsAll patients undergoing convergent PsAF ablation at our centre were retrospectively analys
Externí odkaz:
https://doaj.org/article/4cadebd1676b447d90c6e3f3b70062a8
Autor:
Mark T. Kearney, Karen E. Porter, Richard M Cubbon, Nadira Yuldasheva, Amir Aziz, Hema Viswambharan, Jaswinder K. Sethi, Edward R. Duncan, Shouhong Xuan, Afroze Abbas, Matthew Kahn, Antonio Vidal-Puig, Peter J. Grant, Adil Rajwani, Vivienne A. Ezzat, Helen Imrie, Piruthivi Sukumar, Jessica Smith, Matthew C. Gage, Stephen B. Wheatcroft, Ajay M. Shah
Publikováno v:
Diabetes
Low concentrations of insulin-like growth factor (IGF) binding protein-1 (IGFBP1) are associated with insulin resistance, diabetes, and cardiovascular disease. We investigated whether increasing IGFBP1 levels can prevent the development of these diso
Autor:
Helen Imrie, Edward R. Duncan, Adil Rajwani, Stephen B. Wheatcroft, Ramzi A. Ajjan, Afroze Abbas, Richard M Cubbon, Vivienne A. Ezzat, Peter J. Grant, Matthew Kahn, Mark T. Kearney, Matthew C. Gage, Hema Viswambharan
Publikováno v:
Endocrinology. 150:4575-4582
Obesity and type 2 diabetes mellitus are characterized by insulin resistance, reduced bioavailability of the antiatherosclerotic signaling molecule nitric oxide (NO), and accelerated atherosclerosis. IGF-I, the principal growth-stimulating peptide, w
Publikováno v:
Diabetes, Obesity and Metabolism. 10:198-211
Patients with insulin resistance and type 2 diabetes have an excessive risk of cardiovascular disease (CVD); this increased risk is not fully explained by traditional risk factors such as hypertension and dyslipidaemias. There is now compelling evide
Publikováno v:
Experimental Physiology. 93:158-163
Type 2 diabetes and obesity are major risk factors for the development of cardiovascular atherosclerosis. Resistance to the metabolic effects of insulin on its traditional target tissues (muscle, liver and adipose tissue) is a central pathogenic feat
Autor:
Vivienne A. Ezzat, Mark T. Kearney, Ajay M. Shah, Edward R. Duncan, Stephen B. Wheatcroft, Simon Walker, Jian-Mei Li
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 293:E1311-E1319
Insulin resistance is well established as an independent risk factor for the development of type 2 diabetes and cardiovascular atherosclerosis. Most studies have examined atherogenesis in models of severe insulin resistance or diabetes. However, by t
Autor:
Gary Fuller, Nikki Thomas, Elizabeth Norris, Deborah Yallop, Edward R. Duncan, Swee Lay Thein, Moira C. Dick, Joan Walters, David C. Rees, Sue Height
Publikováno v:
British Journal of Haematology. 136:844-848
The clinical severity of sickle-cell disease (SCD) is dependent on genetic and environmental variables. Environmental factors have been poorly studied. We have investigated possible links between air pollution and acute pain in SCD. We retrospectivel
Autor:
Ross J, Hunter, Victoria, Baker, Malcolm C, Finlay, Edward R, Duncan, Matthew J, Lovell, Muzahir H, Tayebjee, Waqas, Ullah, M Shoaib, Siddiqui, Ailsa, McLEAN, Laura, Richmond, Claire, Kirkby, Matthew R, Ginks, Mehul, Dhinoja, Simon, Sporton, Mark J, Earley, Richard J, Schilling
Publikováno v:
Journal of cardiovascular electrophysiology. 26(12)
Catheter ablation of paroxysmal AF using the Cryoballoon (CRYO) has yielded similar success rates to conventional wide encirclement using radiofrequency catheter ablation (RFCA), but randomized data are lacking. Pilot data suggested a high success ra
Publikováno v:
Current Diabetes Reviews. 2:51-60
A number of population studies have suggested that hyperinsulinaemia is an independent risk factor for the development of cardiovascular atherosclerosis. Furthermore, there is an emerging body of evidence supporting a role for insulin as both a vasor
Autor:
Stephen B. Wheatcroft, Jian-Mei Li, P A Crossey, Edward R. Duncan, BT Noronha, Ajay M. Shah, Mark T. Kearney
Publikováno v:
Diabetes. 53:2645-2652
Type 2 diabetes is preceded by years of insulin resistance and is characterized by reduced bioavailability of the antiatherosclerotic signaling molecule nitric oxide (NO) and premature atherosclerosis. The relationship between resistance to the gluco