Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Edward P. Debold"'
Autor:
Christopher Marang, Brent Scott, James Chambers, Laura K. Gunther, Christopher M. Yengo, Edward P. Debold
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Myosin Va is the molecular motor that drives intracellular vesicular transport, powered by the transduction of chemical energy from ATP into mechanical work. The coupling of the powerstroke and phosphate (Pi) release is key to understanding
Externí odkaz:
https://doaj.org/article/b973fbcda2984834bd41b7df0d6f4025
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract For muscles to effectively power locomotion, trillions of myosin molecules must rapidly attach and detach from the actin thin filament. This is accomplished by precise regulation of the availability of the myosin binding sites on actin (i.e.
Externí odkaz:
https://doaj.org/article/091849787be54845a0c1a0d42faf0dc2
Autor:
Leila Farhadi, Carline Fermino Do Rosario, Edward P. Debold, Aparna Baskaran, Jennifer L. Ross
Publikováno v:
Frontiers in Physics, Vol 6 (2018)
Spontaneous self-organization of active matter has been demonstrated in a number of biological systems including bacteria, cells, and cytoskeletal filaments. Cytoskeletal filaments act as active polar rods when they are propelled along a glass surfac
Externí odkaz:
https://doaj.org/article/16a799c9e03b437db625809b32312cc0
Autor:
Mike Woodward, Edward P. Debold
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Elevated levels of the metabolic by-products, including acidosis (i.e., high [H+]) and phosphate (Pi) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mecha
Externí odkaz:
https://doaj.org/article/5ad8af0838084a0f9ac3c6a65e2b14f3
Autor:
Xiarong Liu, Brent Scott, Seung P. Jeong, Matt Unger, Edward P. Debold, Eric Ostrander, Jianhan Chen, Dhandapani Venkataraman, Mike Woodward
Publikováno v:
Biophys J
Molecular motors have evolved to transduce chemical energy from adenosine triphosphate into mechanical work to drive essential cellular processes, from muscle contraction to vesicular transport. Dysfunction of these motors is a root cause of many pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fde2df2f3695250ecf61f7547b6648
https://doi.org/10.1016/j.bpj.2020.06.024
https://doi.org/10.1016/j.bpj.2020.06.024
Autor:
Edward P. Debold
Publikováno v:
Cytoskeleton (Hoboken)
Myosin is a motor enzyme that converts the chemical energy in ATP into mechanical work to drive a myriad of intracellular processes, from muscle contraction to vesicular transport. Key steps in the transduction of energy are the force-generating powe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e40d1191a47dc72e19ae0add2e5764
https://pubmed.ncbi.nlm.nih.gov/35278035
https://pubmed.ncbi.nlm.nih.gov/35278035
Autor:
Mike K. Woodward, Christopher Marang, Eric Ostrander, Brent Scott, Dhandapani Venkataraman, Edward P. Debold
Publikováno v:
Biophysical Journal. 122:405a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3af95a161482b0df3a41695ce203ff9
https://doi.org/10.1016/j.bpj.2022.11.2202
https://doi.org/10.1016/j.bpj.2022.11.2202
Autor:
Christopher Marang, Brent Scott, James Chambers, Laura K. Gunther, Christopher M. Yengo, Edward P. Debold
Publikováno v:
Biophysical Journal. 122:259a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09e1dbce645e79806089b2a61659e06
https://doi.org/10.1016/j.bpj.2022.11.1493
https://doi.org/10.1016/j.bpj.2022.11.1493
Autor:
Sam Walcott, Shuyue Liu, Christopher Marang, Mike Woodward, Venus Joumaa, Tim Leonard, Brent Scott, Edward P. Debold, Walter Herzog
Publikováno v:
Biophysical Journal. 122:29a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::589f41dd74877acfea4b2395e2461fea
https://doi.org/10.1016/j.bpj.2022.11.377
https://doi.org/10.1016/j.bpj.2022.11.377
Publikováno v:
Optical Trapping and Optical Micromanipulation XVIII.
Myosin is biological molecular motor that transduces the chemical energy ATP hydrolysis into force and/or motion to drives many forms of cellular motility from muscle contraction to cell division. While the transduction process has been extensively s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9b51774b1ec4491b73fdcade797aeb
https://doi.org/10.1117/12.2595724
https://doi.org/10.1117/12.2595724