Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Edward Njoo"'
Autor:
Sophia Li, Emma Wang, Leia Pei, Sourodeep Deb, Prashanth Prabhala, Sai Hruday Reddy Nara, Raina Panda, Shiven Eltepu, Marx Akl, Larry McMahan, Edward Njoo
Publikováno v:
Artificial Intelligence Chemistry, Vol 2, Iss 2, Pp 100078- (2024)
The introduction of fluorine in compounds plays a crucial role in drug development as it greatly influences their final pharmacokinetic and dynamic properties. Due to the prevalence of fluorine in FDA-approved drugs in recent years, identifying the m
Externí odkaz:
https://doaj.org/article/8c8bb13b058d48de96b0962d2a1bb63a
Autor:
Rosie Chen, Pratyush Singh, Sarah Su, Selin Kocalar, Xina Wang, Neha Mandava, Srishti Venkatesan, Adrienne Ferguson, Aishi Rao, Emma Le, Casey Rojas, Edward Njoo
Publikováno v:
ACS Omega. 8:10545-10554
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b4ec15cd2dbea09b5796cd5be4116c
https://doi.org/10.1021/acsomega.3c00290
https://doi.org/10.1021/acsomega.3c00290
Publikováno v:
Canadian Journal of Chemistry.
Carmofur, a 5-fluorouracil (5-FU) derivative, was initially developed as an antineoplastic agent to treat colorectal cancer. Through drug repurposing efforts, it has been identified as a potent covalent inhibitor of the main protease of SARS-CoV-2 (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7212c07481d4aef52692146e3627776
https://doi.org/10.1139/cjc-2022-0266
https://doi.org/10.1139/cjc-2022-0266
Autor:
Rosie Chen, Pratyush Singh, Sarah Su, Selin Kocalar, Xina Wang, Neha Mandava, Srishti Venkatesan, Adrienne Ferguson, Aishi Rao, Emma Le, Casey Rojas, Edward Njoo
Benchtop nuclear magnetic resonance (NMR) spectroscopy has enabled the monitoring and optimization of chemical transformations while simultaneously providing kinetic, mechanistic, and structural insight into reaction pathways with quantitative precis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f36c61f6a3b8428861813c0ede83d0
https://doi.org/10.26434/chemrxiv-2022-1371g
https://doi.org/10.26434/chemrxiv-2022-1371g
Carmofur, a 5-fluorouracil derivative, was initially developed as an antineoplastic agent to treat colorectal cancer. Through drug repurposing efforts, it has been identified as a potent covalent inhibitor of the main protease of SARS-CoV-2 (Mpro), m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83604f8bea25603ad2816532a080b22a
https://doi.org/10.26434/chemrxiv-2022-9213j
https://doi.org/10.26434/chemrxiv-2022-9213j
Autor:
Paul A. Wender, Zachary O. Gentry, David J. Fanelli, Quang H. Luu-Nguyen, Owen D. McAteer, Edward Njoo
Publikováno v:
Nat Chem
Tigilanol tiglate is a natural product diterpenoid in clinical trials for the treatment of a broad range of cancers. Its unprecedented protein kinase C isoform selectivity make it and its analogues exceptional leads for PKC-related clinical indicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e15588a8882c5a3dd8d8b9560d95181
https://pubmed.ncbi.nlm.nih.gov/36192432
https://pubmed.ncbi.nlm.nih.gov/36192432
Autor:
Allen Chen, Ayeeshi Poosarla, Kara Tran, Karthikha Sri Indran, Ayush Bajaj, Harsha Raj, Bhavesh Ashok, Varsha Beldona, Kavya Anand, Jeslyn Wu, Karankumar Mageswaran, Kushal Chattopadhyay, Aishwarya Yuvaraj, Pranjal Verma, Andrew Liang, Edward Njoo, Audrey Kwan, Anvi Surapaneni, Stephanie Sun, Krithikaa Premnath, Atri Surapaneni, Ishani Ashok, Aashi Shah, Tanish Sathish, Ria Kolala, Sarah Su
Publikováno v:
Journal of Student Research. 9
In December of 2019, a novel coronavirus was first identified in Wuhan, China, and has since spread around the world, leaving a largely unsolved biomedical problem in its wake. Upon entry into host cells, the main protease is essential for the replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996effd42d1bb980b0dd441df6c7ca4b
https://doi.org/10.47611/jsrhs.v9i2.1082
https://doi.org/10.47611/jsrhs.v9i2.1082
Autor:
Betssy Jauregui, Kate Menefee, Alissa K. Oakes, Viviane Nguyen, David A. Moffet, Litza Itzel Ledesma Monjaraz, Shannon Pilcher, Crystabel Munoz, Luiza A. Nogaj, Kevin Chang, Dillon J. Rinauro, Jaris Torres, Edward Njoo, Angela Tun, Arleen Lamba, Olivia H. Nossiff, Eileen Olivares, Larry M. Palato, Sarah Shapiro
Publikováno v:
J Pept Sci
The aggregation of the 37-amino acid polypeptide human islet amyloid polypeptide (hIAPP), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of human pancreatic β-islet cells in type 2 diabetes. hIAPP is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a004e4900afc9cc7d71c9e20b81c8265
https://pubmed.ncbi.nlm.nih.gov/31231935
https://pubmed.ncbi.nlm.nih.gov/31231935
Autor:
W. Wesley Dowd, Jeremiah Dallmer, Shaina Alves, Ana Gabriela Jimenez, Edward Njoo, Selina Roa
Publikováno v:
Marine Biology. 163
Organisms inhabiting the rocky intertidal zone must tolerate both aquatic and terrestrial stresses encountered over the tidal cycle, particularly those that occur during emersion such as desiccation, hypoxia, and thermal stress. We tested whether epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54fb2d11ef5cd9ba132c183bc7d6e6b3
https://doi.org/10.1007/s00227-016-2828-8
https://doi.org/10.1007/s00227-016-2828-8