Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Edward N, Janoff"'
Autor:
Samuel Okurut, David R. Boulware, Elizabeth Okafor, Joshua Rhein, Henry Kajumbula, Bernard S. Bagaya, Freddie Bwanga, Joseph O. Olobo, Yukari C. Manabe, David B. Meya, Edward N. Janoff
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSurvival among people with HIV-associated cryptococcal meningitis (CM) remains low, particularly among women, despite the currently optimal use of antifungal drugs. Cryptococcus dissemination into the central nervous system [brain, spinal
Externí odkaz:
https://doaj.org/article/85c7253969b7452594bd58c0ae40b479
Autor:
Edward N. Janoff, Sheldon T. Brown, Ilana Belitskaya-Levy, Jeffrey L. Curtis, Robert A. Bonomo, Elliott K. Miller, Alexa M. Goldberg, Lisa Zehm, Ashlea Wills, Caitlin Hutchinson, Larry J. Dumont, Theresa Gleason, Mei-Chiung Shih
Publikováno v:
Contemporary Clinical Trials Communications, Vol 35, Iss , Pp 101190- (2023)
Background: Effective therapeutics for severe acute respiratory syndrome CoronaVirus-2 (SARS-CoV-2) infection are evolving. Under Emergency Use Authorization, COVID-19 convalescent plasma (CCP) was widely used in individuals hospitalized for COVID-19
Externí odkaz:
https://doaj.org/article/9b6533c71f6841f486856028b909d096
Autor:
Xiyuan Bai, Ashley M. Buckle, Eszter K. Vladar, Edward N. Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B. Fornis, Abraham Majluf-Cruz, Randolph V. Fugit, Brian M. Freed, Soohyun Kim, Robert A. Sandhaus, Edward D. Chan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The cell surface serine protease Transmembrane Protease 2 (TMPRSS2) is required to cleave the spike protein of SARS-CoV-2 for viral entry into cells. We determined whether negatively-charged heparin enhanced TMPRSS2 inhibition by alpha-1-ant
Externí odkaz:
https://doaj.org/article/87deec5add75457e8d052d536d4a5f93
Autor:
Kadi J. Horn, Alexander C. Jaberi Vivar, Vera Arenas, Sameer Andani, Edward N. Janoff, Sarah E. Clark
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
The stability and composition of the airway microbiome is an important determinant of respiratory health. Some airway bacteria are considered to be beneficial due to their potential to impede the acquisition and persistence of opportunistic bacterial
Externí odkaz:
https://doaj.org/article/3f96c7718ddb45c3a34d55a21462339f
Autor:
Xiyuan Bai, Ashley M. Buckle, Eszter K. Vladar, Edward N. Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B. Fornis, Abraham Majluf-Cruz, Randolph V. Fugit, Brian M. Freed, Soohyun Kim, Robert A. Sandhaus, Edward D. Chan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/00ca77f49f1541f1b75658582a402a13
Autor:
Elliott K Miller, Alexa M Goldberg, Edward N Janoff, Sheldon T Brown, Jeffrey L Curtis, Robert A Bonomo, Mei-Chiung Shih, Theresa C Gleason
Publikováno v:
Clinical Trials. 19:137-145
Background: Success in conducting clinical trials during the coronavirus disease of 2019 pandemic requires the ability to innovate and adapt. There are well-established procedures for the blinding of investigational agents, especially medications, in
Publikováno v:
Yamada's Atlas of Gastroenterology. :588-595
Autor:
Scott W Mueller, Laura J Baumgartner, Rob MacLaren, Robert Neumann, Arek J Wiktor, Tyree H Kiser, Gordon Lindberg, Luis Cava, Douglas N Fish, Edward N Janoff
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197037 (2018)
Critically ill hospitalized patients are at increased risk of infection so we assessed the immunogenicity of 23-valent pneumococcal polysaccharide vaccine (PPSV23) administered within six days of injury.This prospective observational study compared t
Externí odkaz:
https://doaj.org/article/8c7a5fe9b72f474f8928130cc3816da9
Autor:
Sean T. Jones, Kejun Guo, Emily H. Cooper, Stephanie M. Dillon, Cheyret Wood, David H. Nguyen, Guannan Shen, Bradley S. Barrett, Daniel N. Frank, Miranda Kroehl, Edward N. Janoff, Katerina Kechris, Cara C. Wilson, Mario L. Santiago
Publikováno v:
Journal of virology. 96(17)
Humoral immune perturbations contribute to pathogenic outcomes in persons with HIV-1 infection (PWH). Gut barrier dysfunction in PWH is associated with microbial translocation and alterations in microbial communities (dysbiosis), and IgA, the most ab
Autor:
Edward M. Gardner, Lindsay K. Nicholson, Edward N. Janoff, James Scott, Vibha Jha, Jordan Jacobelli, Jeremy T Rahkola, Mandy Borgeson, Harsh Pratap
Publikováno v:
The Journal of Immunology. 206:2402-2411
Pneumococcal infections are common and serious complications of HIV-1 disease. Prevention has been compromised by the limited magnitude and quality of Ab responses to T cell–independent type 2 pneumococcal capsular polysaccharides (PPS). The pneumo