Protein kinase R-like endoplasmic reticulum kinase is a mediator of stretch in ventilator-induced lung injury

Autor: Tamás Dolinay, Chanat Aonbangkhen, William Zacharias, Edward Cantu, Jennifer Pogoriler, Alec Stablow, Gladys G. Lawrence, Yoshikazu Suzuki, David M. Chenoweth, Edward Morrisey, Jason D. Christie, Michael F. Beers, Susan S. Margulies

Publikováno v: Respiratory Research, Vol 19, Iss 1, Pp 1-14 (2018)

Abstract Background Acute respiratory distress syndrome (ARDS) is a severe form of lung injury characterized by damage to the epithelial barrier with subsequent pulmonary edema and hypoxic respiratory failure. ARDS is a significant medical problem in

Externí odkaz: https://doaj.org/article/6fe2820182074f49a0dfbaa78e1cc09d

Author Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry

Autor: John Kee, Samuel Thudium, David M. Renner, Karl Glastad, Katherine Palozola, Zhen Zhang, Yize Li, Yemin Lan, Joseph Cesare, Andrey Poleshko, Anna A. Kiseleva, Rachel Truitt, Fabian L. Cardenas-Diaz, Xianwen Zhang, Xuping Xie, Darrell N. Kotton, Konstantinos D. Alysandratos, Jonathan A. Epstein, Pei-Yong Shi, Wenli Yang, Edward Morrisey, Benjamin A. Garcia, Shelley L. Berger, Susan R. Weiss, Erica Korb

Publikováno v: Nature. 614:E44-E44

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::620c4166e9643733bb13a81e9a305a40
https://doi.org/10.1038/s41586-023-05764-8

National heart, lung and blood institute and building respiratory epithelium and tissue for health (BREATH) consortium workshop report: Moving forward in lung regeneration

Autor: Sam M. Janes, Carla F. Kim, Qing S. Lin, Reinoud Gosens, Robert E. Hynds, Oliver Eickelberg, Amy L. Ryan, Xin Sun, Edward Morrisey, William J. Zacharias, Hans Clevers, Paolo de Coppi, Marko Nikolic, Barry R. Stripp, Melanie Königshoff

Publikováno v: Am. J. Respir. Cell Mol. Biol. 65, 22-29 (2021)
American Journal of Respiratory Cell and Molecular Biology, 65(1), 22-29. AMER THORACIC SOC
Am J Respir Cell Mol Biol
American journal of respiratory cell and molecular biology, 65(1), 22-29

The National Heart, Lung, and Blood Institute of the National Institutes of Health, together with the Longfonds BREATH consortium, convened a working group to review the field of lung regeneration and suggest avenues for future research. The meeting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718756268ff00913ef04cbc46a877084
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61483

Abstract 329: CRISPR/Cas-mediated Gene Editing in Human iPSC-derived Macrophage Reveals Lysosomal Acid Lipase Functions in Human Macrophages

Autor: Hanrui Zhang, Wenjun Li, Christine Hinkle, Xuan Zhang, Robert Bauer, Junichiro Tohyama, Kevin Patel, Kevin Trindade, Jennie Lin, John Millar, Jeffrey Billheimer, Wenli Yang, Edward Morrisey, Michael C Phillips, Daniel J Rader, Muredach P Reilly

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 35

Loss-of-function mutations of lysosomal acid lipase ( LIPA or LAL) are the cause of the rare lysosomal disorders, Wolman disease and Cholesteryl Ester Storage Disease (CESD), which manifest with hepatomegaly, hyperlipidemia and premature atherosclero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9668e0e2add8d7fe60ab99c4e33d9727
https://doi.org/10.1161/atvb.35.suppl_1.329

Foxp1 and Foxp4 regulate Foxp3+ nTreg generation in the thymus (P4420)

Autor: Karla Wiehagen, Elizabeth Staub, Haley Tucker, Edward Morrisey, Jonathan Maltzman

Publikováno v: The Journal of Immunology. 190:52.30-52.30

CD4+ Foxp3+ regulatory T cells (Tregs) are fundamental for transplantation tolerance and prevention of autoimmunity. nTreg generation occurs in the thymus and requires both T cell receptor- and cytokine receptor-generated signals. Foxp1 and Foxp4 are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a38d12520787ce5a78e8ac4063e4ea4
https://doi.org/10.4049/jimmunol.190.supp.52.30