Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Edward Millgate"'
Autor:
George Gifford, Alexis E. Cullen, Sandra Vieira, Anja Searle, Robert A. McCutcheon, Gemma Modinos, William S. Stone, Emily Hird, Jennifer Barnett, Hendrika H. van Hell, Ana Catalan, Edward Millgate, Nick Taptiklis, Francesca Cormack, Margot E. Slot, Paola Dazzan, Arija Maat, Lieuwe de Haan, Benedicto Crespo Facorro, Birte Glenthøj, Stephen M. Lawrie, Colm McDonald, Oliver Gruber, Thérèse van Amelsvoort, Celso Arango, Tilo Kircher, Barnaby Nelson, Silvana Galderisi, Rodrigo A. Bressan, Jun Soo Kwon, Mark Weiser, Romina Mizrahi, Gabriele Sachs, Matthias Kirschner, Abraham Reichenberg, René Kahn, Philip McGuire
Publikováno v:
Schizophrenia Research: Cognition, Vol 37, Iss , Pp 100310- (2024)
Despite the functional impact of cognitive deficit in people with psychosis, objective cognitive assessment is not typically part of routine clinical care. This is partly due to the length of traditional assessments and the need for a highly trained
Externí odkaz:
https://doaj.org/article/bf74cdebd23540a998210fa727352629
Autor:
Rebecca Owens, Rebecca Pollard, Richard Drake, Laura Kassoumeri, Shon Lewis, James MacCabe, Oliver D Howes, Edward Millgate, Eugenia Kravariti, Alice Egerton, Jane Lees, Bill Deakin, Kira Griffiths, Cecilia Casetta, Sobia Khan, Steve Lankshear, Elena Mikulskaya, Ebenezer Oloyede, Nathalie Rich, Sophie Smart, Aviv Segev, Kyra Verena Sendt
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Objectives This prospective cohort study tested for associations between baseline cognitive performance in individuals early within their first episode and antipsychotic treatment of psychosis. We hypothesised that poorer cognitive functioning at the
Externí odkaz:
https://doaj.org/article/24b84b4f0e3248a4be25b8fa5a018358
Autor:
Robin M Murray, Richard Drake, Stephen Lawrie, Laura Kassoumeri, James Walters, Shon Lewis, Anna Murphy, James MacCabe, Oliver D Howes, Edward Millgate, Eugenia Kravariti, Alice Egerton, Jacek Donocik, Tracy Collier, Jane Lees, Charlotte Stockton-Powdrell, Bill Deakin
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Background 70%–84% of individuals with antipsychotic treatment resistance show non-response from the first episode. Emerging cross-sectional evidence comparing cognitive profiles in treatment resistant schizophrenia to treatment-responsive schizoph
Externí odkaz:
https://doaj.org/article/5c29a747d3fb491da3842a8728ebc56a
Autor:
Alice Egerton, Kira Griffiths, Cecila Casetta, John Deakin, Richard Drake, Oliver Howes, Laura Kassoumeri, Sobia Khan, Steve Lankshear, Jane Lees, Shôn Lewis, Elena Mikulskaya, Edward Millgate, Ebenezer Oloyede, Rebecca Pollard, Nathalie Rich, Aviv Segev, Kyra-Verena Sendt, James MacCabe
Publikováno v:
Neuropsychopharmacology. 48:567-575
Elevated brain glutamate has been implicated in non-response to antipsychotic medication in schizophrenia. Biomarkers that can accurately predict antipsychotic non-response from the first episode of psychosis (FEP) could allow stratification of patie
Publikováno v:
Neuroscience & Biobehavioral Reviews. 131:497-524
Theory of Mind (ToM), the ability to represent the mental states of oneself and others, is an essential social skill disrupted across many psychiatric conditions. The transdiagnostic nature of ToM impairment means it is plausible that ToM impairment
Autor:
Eugenia Kravariti, Robin M. Murray, Olga Hide, James H. MacCabe, Stephen M. Lawrie, Edward Millgate
Publikováno v:
Psychological Medicine
Millgate, E, Hide, O, Lawrie, S M, Murray, R M, MacCabe, J H & Kravariti, E 2021, ' Neuropsychological differences between treatment-resistant and treatment-responsive schizophrenia : a meta-analysis ', Psychological Medicine, vol. 52, no. 1, pp. 1-13 . https://doi.org/10.1017/S0033291721004128
Millgate, E, Hide, O, Lawrie, S M, Murray, R M, MacCabe, J H & Kravariti, E 2021, ' Neuropsychological differences between treatment-resistant and treatment-responsive schizophrenia : a meta-analysis ', Psychological Medicine, vol. 52, no. 1, pp. 1-13 . https://doi.org/10.1017/S0033291721004128
Antipsychotic treatment resistance affects up to a third of individuals with schizophrenia. Of those affected, 70–84% are reported to be treatment resistant from the outset. This raises the possibility that the neurobiological mechanisms of treatme
Autor:
Kira Griffiths, Alice Egerton, Edward Millgate, Adriana Anton, Gareth J. Barker, Bill Deakin, Richard Drake, Emma Eliasson, Catherine J. Gregory, Oliver D. Howes, Eugenia Kravariti, Stephen M. Lawrie, Shôn Lewis, David J. Lythgoe, Anna Murphy, Philip McGuire, Scott Semple, Charlotte Stockton-Powdrell, James T. R. Walters, Stephen R. Williams, James H. MacCabe
Publikováno v:
Griffiths, K, Egerton, A, Millgate, E, Anton, A, Barker, G J, Deakin, B, Drake, R, Eliasson, E, Gregory, C J, Howes, O D, Kravariti, E, Lawrie, S M, Lewis, S, Lythgoe, D J, Murphy, A, McGuire, P, Semple, S, Stockton-Powdrell, C, Walters, J T R, Williams, S R & MacCabe, J H 2022, ' Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia : findings from the STRATA study ', Schizophrenia (Heidelberg, Germany), vol. 8, no. 1, pp. 60 . https://doi.org/10.1038/s41537-022-00265-5
Schizophrenia
Schizophrenia
Impaired cognition is associated with lower quality of life and poor outcomes in schizophrenia. Brain glutamate may contribute to both clinical outcomes and cognition, but these relationships are not well-understood. We studied a multicentre cohort o
Autor:
Tracy Collier, Bill Deakin, Charlotte Stockton-Powdrell, Robin M. Murray, James H. MacCabe, Jane Lees, Alice Egerton, Richard Drake, Edward Millgate, Jacek Donocik, Shôn Lewis, James T.R. Walters, Oliver D. Howes, Eugenia Kravariti, Anna Murphy, Stephen M. Lawrie, Laura Kassoumeri
Publikováno v:
BMJ Open
King's College London
Millgate, E, Kravariti, E, Egerton, A, Howes, O D, Murray, R M, Kassoumeri, L, Donocik, J, Lewis, S, Drake, R, Lawrie, S, Murphy, A, Collier, T, Lees, J, Stockton-powdrell, C, Walters, J, Deakin, B & Maccabe, J 2021, ' Cross-sectional study comparing cognitive function in treatment responsive versus treatment non-responsive schizophrenia: evidence from the STRATA study ', BMJ Open, vol. 11, no. 11, pp. e054160 . https://doi.org/10.1136/bmjopen-2021-054160
BMJ Open, Vol 11, Iss 11 (2021)
King's College London
Millgate, E, Kravariti, E, Egerton, A, Howes, O D, Murray, R M, Kassoumeri, L, Donocik, J, Lewis, S, Drake, R, Lawrie, S, Murphy, A, Collier, T, Lees, J, Stockton-powdrell, C, Walters, J, Deakin, B & Maccabe, J 2021, ' Cross-sectional study comparing cognitive function in treatment responsive versus treatment non-responsive schizophrenia: evidence from the STRATA study ', BMJ Open, vol. 11, no. 11, pp. e054160 . https://doi.org/10.1136/bmjopen-2021-054160
BMJ Open, Vol 11, Iss 11 (2021)
Background70%–84% of individuals with antipsychotic treatment resistance show non-response from the first episode. Emerging cross-sectional evidence comparing cognitive profiles in treatment resistant schizophrenia to treatment-responsive schizophr
Autor:
Edward Millgate, Kira Griffiths, Alice Egerton, Eugenia Kravariti, Cecilia Casetta, Bill Deakin, Richard Drake, Oliver D Howes, Laura Kassoumeri, Sobia Khan, Steve Lankshear, Jane Lees, Shon Lewis, Elena Mikulskaya, Ebenezer Oloyede, Rebecca Owens, Rebecca Pollard, Nathalie Rich, Sophie Smart, Aviv Segev, Kyra Verena Sendt, James MacCabe
Publikováno v:
BMJ Open. 12:e062570
ObjectivesThis prospective cohort study tested for associations between baseline cognitive performance in individuals early within their first episode and antipsychotic treatment of psychosis. We hypothesised that poorer cognitive functioning at the
Publikováno v:
Psychological medicine. 51(3)
Clozapine is the only licensed pharmacotherapy for treatment-resistant schizophrenia. However, response to clozapine is variable. Understanding the demographic and clinical features associated with response to clozapine may be useful for patient stra