Výsledky vyhledávání - "Edward Mascioli"

Safety, Pharmacokinetic, and Pharmacodynamic Evaluations of PI-2301, a Potent Immunomodulator, in a First-in-Human, Single-Ascending-Dose Study in Healthy Volunteers

Autor: Edward Mascioli, Nicolas Fauchoux, Jeffrey Krieger, Michelle Genova, E. Lacoste, Joseph Kovalchin, Michael Augustyniak, Kathy Collins, Tony Avril, Claire Toutin, Uday Patel, Eric Zanelli, Alain Patat, Gwenola Gandon, Allyson Masci

Publikováno v: The Journal of Clinical Pharmacology. 51:649-660

PI-2301 is an amino acid copolymer acting as an immunomodulator for the treatment of autoimmune diseases. The present study evaluated the safety, pharmacokinetics (PK), and pharmacodynamics of PI-2301 in a single ascending dose, first-in-human study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6203d2e89a9eb5af40e65ec24b172f29
https://doi.org/10.1177/0091270010373930

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Sa.98. Preclinical and Clinical Development of a Second Generation Peptide Copolymer for the Treatment of Multiple Sclerosis

Autor: Uday Patel, Joseph Kovalchin, Michelle Genova, Kristen Rafuse, Eric Zanelli, Alain Patat, Ingrid Dufour, Michael Augustyniak, Edward Mascioli, Jeffrey Krieger, Kathy Collins

Publikováno v: Clinical Immunology. 127:S112-S113

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e1535fd978254f66f380aa331c74427
https://doi.org/10.1016/j.clim.2008.03.319

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