Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Edward M. Tyndall"'
Autor:
Barbara Frey, Kate Porter, Veronika Wirth, Jesse D. Thomas, Silas Bond, Saba Jahangiri, Brett Pool, Angela Luttick, Alistair George Draffan, Rosliana Halim, Danielle Tilmanis, Edward M. Tyndall, Simon P. Tucker
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:869-873
A number of prodrugs of HCV-active purine nucleoside analogues 2'-C-methyl 4-aza-9-deaza adenosine 1, 2'-C-methyl 4-aza-7,9-dideaza adenosine 2, 2'-C-methyl 4-aza-9-deaza guanosine 3 and 2'-C-methyl 4-aza-7,9-dideaza guanosine 4 were prepared and eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa16284d79ae4c4495f5548c3272dfcd
https://doi.org/10.1016/j.bmcl.2014.12.069
https://doi.org/10.1016/j.bmcl.2014.12.069
Autor:
Craig J. Morton, Barbara Frey, George Kukolj, Alistair George Draffan, Van T. T. Nguyen, Angela Luttick, Tyrone Pieter Jeynes, Ginette McKercher, Bruno Simoneau, Richard Hufton, Kate Porter, Danielle Tilmanis, Bo Lin, Simon P. Tucker, Jesse D. Thomas, Melinda J. Pryor, Jianmin Duan, Lilly Michael John, Paula Francom, Edward M. Tyndall, Silas Bond, Lisette Lagacé, Carlie T. Gannon, Ma’an Amad, Veronika Wirth, Rosliana Halim, Richard Bethell, Saba Jahangiri, Brett Pool
Publikováno v:
ACS Medicinal Chemistry Letters. 5:679-684
Nucleoside analogues have long been recognized as prospects for the discovery of direct acting antivirals (DAAs) to treat hepatitis C virus because they have generally exhibited cross-genotype activity and a high barrier to resistance. C-Nucleosides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2b73cd6b0e37544386aa833a0c233c
https://doi.org/10.1021/ml500077j
https://doi.org/10.1021/ml500077j
Autor:
Guy Y. Krippner, Angelo Dominic D'Elia, Peter J. Duggan, Vijaya Bhaskar, Trang T. Nhan, David Humphrey, Edward M. Tyndall
Publikováno v:
Journal of Carbohydrate Chemistry. 22:867-879
The influence of phenylboronic acid on the silylation of d‐mannitol by TBDMSCl and TBDPSCl has been investigated. Terminal silyation was found to dominate, with PBA significantly enhancing the yield of 1,6 di‐TBDMS d‐mannitol compared to the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0a6337c9bea774f2a18efd166ad74d
https://doi.org/10.1081/car-120026598
https://doi.org/10.1081/car-120026598
Autor:
Edward M. Tyndall, Peter J. Duggan
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1325-1339
Covering: 1978–2000. Previous review: R. J. Ferrier, Adv. Carbohydr. Chem. Biochem., 1978, 35, 31–80.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::611ec09488321b5549ebb4e5309a7baf
https://doi.org/10.1039/b006767i
https://doi.org/10.1039/b006767i
Autor:
Richard Hufton, Jianmin Duan, Carlie T. Gannon, Tyrone Pieter Jeynes, Barbara Frey, George Kukolj, Alistair George Draffan, Rosliana Halim, Van T. T. Nguyen, Benjamin H. Fraser, Bruno Simoneau, Melinda J. Pryor, Edward M. Tyndall, Lilly Michael John, Kate Porter, Michael Harding, Silas Bond, Julia Cianci, Brett Pool, Simon P. Tucker, Bo Lin, Danielle Tilmanis, Angela Luttick, Saba Jahangiri, Veronika Wirth, Richard Bethell, Craig J. Morton
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(21)
Previous investigations identified 2′-C-Me-branched ribo-C-nucleoside adenosine analogues, 1, which contains a pyrrolo[2,1-f][1,2,4]triazin-4-amine heterocyclic base, and 2, which contains an imidazo[2,1-f][1,2,4]triazin-4-amine heterocyclic base a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c181f524b8d49fb1f84a67ab334ead
https://pubmed.ncbi.nlm.nih.gov/25288185
https://pubmed.ncbi.nlm.nih.gov/25288185
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 61:o1733-o1735
The title compound, C18H18B2O6, was formed by the reaction between phenylboronic acid and d-glucose. The structure is analogous to those of d-glucoboronates previously prepared and characterized by NMR. In the crystal structure, molecules are lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57578825130fba2e7656c488297e3b1e
https://doi.org/10.1107/s1600536805014480
https://doi.org/10.1107/s1600536805014480
Autor:
Ian Collins, Anil K Srivastava, Piyush K. Agarwal, John Frederick Atherall, Paul Lancett, Amit Kumar Singh, Pitt Gary Robert William, David T. Davies, Laura Andrau, Christopher Richard Steele, James M. Bennett, Stephanie Barker, James T Palmer, Mahipal Singh, Lorraine C. Axford, Carlie T. Gannon, Dushyant Kumar, David J. Haydon, Nicholas John Palmer, Daniel J. Price, Tarun Shukla, Daniel A. Offermann, Edward M. Tyndall, David G. Watson, Michael Blair, Helena Thomaides-Brears, Kelly Helen Anderson, Dale Robert Mitchell, Neil R. Stokes, Lloyd George Czaplewski, Stéphanie Pommier, Christopher J. Lunniss, Alastair Logan, Rashmi Saxena, B. Narasinga Rao
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(24)
The discovery and optimisation of a new class of benzothiazole small molecules that inhibit bacterial DNA gyrase and topoisomerase IV are described. Antibacterial properties have been demonstrated by activity against DNA gyrase ATPase and potent acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f31d292e80ee8ea7fb2998f08dcb4ae
https://pubmed.ncbi.nlm.nih.gov/24239017
https://pubmed.ncbi.nlm.nih.gov/24239017
Autor:
Peter J. Duggan, Edward M. Tyndall
Publikováno v:
ChemInform. 33
Covering: 1978–2000. Previous review: R. J. Ferrier, Adv. Carbohydr. Chem. Biochem., 1978, 35, 31–80.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667bb3b90d6790413f576280ef518131
https://doi.org/10.1002/chin.200235281
https://doi.org/10.1002/chin.200235281
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 59:o372-o373
The title compound, C32H28B2O8, was obtained by the condensation of 1,6-dibenzoyloxy-d-mannitol with two equivalents of phenylboronic acid. The crystal structure confirms that the phenylboronate moieties exist as six-membered rings in the sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae19408b029bb399e96ddc1240166e1a
https://doi.org/10.1107/s1600536803004069
https://doi.org/10.1107/s1600536803004069
Publikováno v:
Australian Journal of Chemistry. 64:495
Four new tetra-n-butylammonium spiroborates derived from dimethyl, diethyl, di-iso-propyl and di-n-butyl esters of l-tartaric acid have been prepared and their potential as environmentally benign wood protectants investigated. These compounds showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aede075be9671e1b02d9a5e308b9653
https://doi.org/10.1071/ch11022
https://doi.org/10.1071/ch11022