Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Edward M. Tilmont"'
Autor:
Julie A. Mattison, Richard Herbert, Balmiki Ray, Debomoy K. Lahiri, Gregory P. Tinkler, Mary Ann Ottinger, Edward M. Tilmont, Nigel H. Greig, Donald K. Ingram, Kara B. Duffy
The degeneration in the locus coeruleus associated with Alzheimer’s disease suggests an involvement of the noradrenergic system in the disease pathogenesis. The role of depleted norepinephrine was tested in adult and aged rhesus macaques to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac6e6c81e36ba0c32bc755d23ea22b0
https://europepmc.org/articles/PMC6710827/
https://europepmc.org/articles/PMC6710827/
Autor:
Steven S. An, Sung-Soo Park, Stuart Maudsley, Leonid Peshkin, Julie A. Mattison, Shakeela Faulkner, Bronwen Martin, Richard Herbert, Mingyi Wang, Kevin J. Pearson, Danuta Sosnowska, Christopher H. Morrell, Edward G. Lakatta, Anna Csiszar, Zoltan Ungvari, Lakshmi Santhanam, Jing Zhang, Michel Bernier, Rafael de Cabo, Joseph A. Baur, Edward M. Tilmont
Publikováno v:
Cell Metabolism. 20(1):183-190
Summary Central arterial wall stiffening, driven by a chronic inflammatory milieu, accompanies arterial diseases, the leading cause of cardiovascular (CV) morbidity and mortality in Western society. An increase in central arterial wall stiffening, me
Autor:
Jennifer L. Huck, Donald K. Ingram, Julie A. Mattison, Tammy Moscrip, Edward M. Tilmont, George S. Roth, Mark A. Lane, A. Black, April M. Handy
Publikováno v:
Neurobiology of Aging. 26:1117-1127
Human studies have documented age-related declines in caloric intake that are pronounced at advanced ages. We examined caloric intake from a longitudinal study of aging in 60 male and 60 female rhesus monkeys (Macaca mulatta) collected for up to 10 y
Autor:
Mark A. Lane, Edward M. Tilmont, J. A. Mattison, George S. Roth, April M. Handy, Donald K. Ingram
Publikováno v:
Hormone and Metabolic Research. 34:378-382
Plasma levels of thyroid hormones - triiodothyronine (T 3 ), thyroxin (T 4 ), and thyroid-stimulating hormone (TSH) were measured in male and female rhesus monkeys (Macaca mulatta) fed either ad libitum or a 30 % calorie-restricted (CR) diet (males f
Autor:
George S. Roth, William V. Rumpler, Mark A. Lane, A. Black, David J. Baer, Donald K. Ingram, Edward M. Tilmont
Publikováno v:
Journal of Medical Primatology. 30:94-99
Accuracy of body composition measurements by dual-energy X-ray absorptiometry (DXA) was compared with direct chemical analysis in 10 adult rhesus monkeys. DXA was highly correlated (r-values > 0.95) with direct analyses of body fat mass (FM), lean ma
Autor:
A. Black, George S. Roth, David B. Allison, Donald K. Ingram, Edward M. Tilmont, Mark A. Lane, April M. Handy, Sue A. Shapses
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 56:B98-B107
Little is known regarding the effects of prolonged calorie restriction (CR) on skeletal health. We investigated long-term (11 years) and short-term (12 months) effects of moderate CR on bone mass and biochemical indices of bone metabolism in male rhe
Autor:
Edward M. Tilmont, George S. Roth, Sue A. Shapses, A. Black, Donald K. Ingram, Mark A. Lane, April M. Handy, Tara L. Kiefer
Publikováno v:
The Journal of Nutrition. 131:820-827
Energy restriction (ER) extends the life span and slows aging and age-related diseases in short-lived mammalian species. Although a wide variety of physiological systems have been studied using this paradigm, little is known regarding the effects of
Autor:
Edward M. Tilmont, Josephine M. Egan, Mitesh Sanghvi, María M. Malagón, Christopher H. Morrell, Plácido Navas, Caitlin M. Younts, Yolanda Jimenez-Gomez, Theresa M. Ward, Jonathan S. Bogan, Kaitlyn N. Lewis, Joanne S. Allard, Julie A. Mattison, Luigi Ferrucci, Alex M. Sossong, Richard Herbert, Joseph A. Baur, Dan L. Longo, Ruin Moaddel, Rafael de Cabo, Alejandro Martin-Montalvo, Kevin J. Pearson, Michel Bernier, Jonathan P. Belman, Hector H. Palacios
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
PMID:24093677.-- et al.
Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes. Resveratrol, a natural compound with anti-inflammatory properties, i
Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes. Resveratrol, a natural compound with anti-inflammatory properties, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af1f7769e7d87ab243d9dcb1541b0b8
http://hdl.handle.net/10261/129202
http://hdl.handle.net/10261/129202
Autor:
George S. Roth, T. Mark Beasley, Mark Bryant, Edward M. Tilmont, Wenbo Qi, Julie A. Mattison, Richard Herbert, Walter F. Ward, Dan L. Longo, April M. Handy, Donald K. Ingram, Rafael de Cabo, David B. Allison, Jennifer E. Young, Dennis Barnard
Publikováno v:
Nature. 489(7415)
Calorie restriction (CR), a reduction of 10–40% in intake of a nutritious diet, is often reported as the most robust non-genetic mechanism to extend lifespan and healthspan. CR is frequently used as a tool to understand mechanisms behind ageing and
Autor:
Navin Maswood, Peter R. Mouton, Edward M. Tilmont, Zhiming Zhang, George S. Roth, Don M. Gash, Donald K. Ingram, Greg A. Gerhardt, Mark P. Mattson, Jennifer E. Young, Julie A. Mattison, Christopher Quigley, Robert M. Cohen, Richard Grondin, Richard E. Carson, Mark A. Lane
We report that a low-calorie diet can lessen the severity of neurochemical deficits and motor dysfunction in a primate model of Parkinson's disease. Adult male rhesus monkeys were maintained for 6 months on a reduced-calorie diet [30% caloric restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdff81b83fda8e02b7cf1a45b3abecc
https://europepmc.org/articles/PMC539733/
https://europepmc.org/articles/PMC539733/