Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edward M. O'Mara"'
Autor:
Pratapa Prasad, Edward M. O'Mara, James McLeod, Richard A. Preston, Allen Moton, Gopal Krishna, Lei Ma
Publikováno v:
Current Medical Research and Opinion. 26:1-7
To evaluate posaconazole pharmacokinetics in subjects with different degrees of hepatic impairment compared with matched healthy subjects.A total of 37 subjects were enrolled in this open-label, single-dose, parallel-group study; 19 with hepatic impa
Publikováno v:
Infection Control and Hospital Epidemiology. 19:28-31
An outbreak investigation was conducted to determine if an increase in bloodstream infections (BSIs) in patients with central venous catheters (CVC) had occurred. Because other methods of obtaining CVC days were not feasible, we used an estimation me
Autor:
Susan Temporado Cookson, Melanie Ihrig, Edward M. O'Mara, Alan I. Hartstein, William R. Jarvis
Publikováno v:
Infection Control and Hospital Epidemiology. 19:28-31
Autor:
Shailen N. Banerjee, Alan I. Hartstein, William R. Jarvis, Mark A. Denny, Edward M. O'Mara, Helen M. Volk, Melanie Ihrig, Susan T. Cookson
Publikováno v:
Infection Control and Hospital Epidemiology. 19:23-27
Objective: To determine if an apparent increase in bloodstream infections (BSIs) in patients with central venous catheters (CVCs) was associated with the implementation of a needleless access device. Design: Retrospective cohort study using a derived
Autor:
Edward M. O'Mara, David R. Jones, Barbara D. Haehner‐Daniels, Mitchell A. Hamman, J. Christopher Gorski, Stephen D. Hall
Publikováno v:
Clinical pharmacology and therapeutics. 64(2)
Objective To assess the relative contribution of intestinal and hepatic CYP3A inhibition to the interaction between the prototypic CYP3A substrates midazolam and clarithromycin. Methods On day 1, 16 volunteers (eight men and eight women; age range, 2
Autor:
Stanley M. Spinola, Ronald E. Shoup, Edward M. O'Mara, Kate R. Fortney, Alice C. Thornton, Thomas J. Hiltke, Suellyn J. Sorensen, Barry P. Katz, Antoinette F. Hood
Publikováno v:
The Journal of infectious diseases. 177(6)
Human subjects were infected with Haemophilus ducreyi. All subjects developed papules and were randomized to treatment with a single dose of azithromycin (1 g) or ciprofloxacin (500 mg). At weekly intervals, volunteers were reinoculated with H. ducre
Publikováno v:
Clinical pharmacology and therapeutics. 60(4)
Dextromethorphan is used widely in vivo to phenotype the polymorphically expressed cytochrome P450 (CYP) 2D6. Dextromethorphan is N-demethylated in vitro to 3-methoxymorphinan by human CYP3A4/5. We examined whether the dextromethorphan/3-methoxymorph