Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Edward M. Hoffmann"'
Publikováno v:
Veterinary microbiology. 68(3-4)
It was shown in this study that complement-resistant Brucella abortus used were unable to activate complement in the absence of specific antibody. Complement-resistant isolates possessed O-antigen, but complement-sensitive organisms used are O-antige
Contradictory roles for antibody and complement in the interaction of Brucella abortus with its host
Autor:
Edward M. Hoffmann, Jeri Joan Houle
Publikováno v:
Critical reviews in microbiology. 21(3)
The ability of serum complement to kill bacteria has been linked to host resistance to Gram-negative bacteria. A mechanism for killing extracellular organisms during early invasion, following release from infected phagocytic cells, or during bacterem
The use of a passive hemolysis system to evaluate the complement activities of six mammalian species
Autor:
Jeri Joan Houle, Edward M. Hoffmann
Publikováno v:
Veterinary Immunology and Immunopathology. 16:259-270
A passive hemolysis assay system was developed which permitted comparisons of the hemolytic activities of complement (C) from six species. This system employs a single antigen and an antiserum raised in one species. Thus, variations resulting from di
Publikováno v:
Blood. 55:772-776
Extracts of the membranes of normal red cells and red cells from all subpopulations of paroxysmal nocturnal (PNH) red cells inhibited antibody-mediated complement activation. These extracts were shown to accelerate decay of the complement complex. C4
Publikováno v:
The Journal of Immunology. 122:54-60
A cell-free extract from the spent medium of Streptococcus mutans BHT was tested for anti-complementary activity with sheep erythrocytes (E) as target cells. It was determined that this extract was enriched for extracellular lipoteichoic acid (LTA) a
Autor:
Clifford M. Renk, Edward M. Hoffmann
Publikováno v:
The Journal of Immunology. 119:263-270
A factor capable of inhibiting complement was obtained from intact Ehrlich ascites tumor cells by mild extraction with phosphate-buffered saline (PBS). The inhibitor caused a decrease in extent of lysis of EAC with a concomitant extension of Tmax. EA
Publikováno v:
Journal of Immunological Methods. 10:293-299
Sucrose (15% w/v) was found to be a useful agent for cryopreservation of sheep erythrocytes in the intermediate state EAC 142 . The ordinarilly very labile SAC 142 , associated with the cells, did not decay to any appreciable degree during periods of
Publikováno v:
Blood. 71:287-292
Our previous work revealed that homologous complement (C) was ineffective in lysing antibody-sensitized erythrocytes (EA) even at high concentrations. It was also shown that activation of complement on homologous EA resulted in the binding of C9 and
Publikováno v:
Blood. 71:280-286
The hemolytic efficiency and binding of C9 to homologous and heterologous erythrocytes was evaluated by using a standardized passive sensitization procedure to prepare antigen- and antibody-coated erythrocytes (EA) and human serum for lysis. Heterolo
Publikováno v:
Journal of Invertebrate Pathology. 33:1-9
The blue crab, Callinectes sapidus, was found to possess a naturally occurring humoral factor which neutralizes T2 bacteriophage in a relatively specific fashion. The molecule responsible for this neutralization was isolated from crab plasma and show