Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Edward M. Driggers"'
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Top 200 genes by KS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aba35809716d259c0721faa29d78f09
https://doi.org/10.1158/2159-8290.22530554.v1
https://doi.org/10.1158/2159-8290.22530554.v1
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Top 100 shRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5494b2cfe05aa2c20a308fc28efe94
https://doi.org/10.1158/2159-8290.22530563
https://doi.org/10.1158/2159-8290.22530563
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
70 genes selected for validation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1327cbfd0a3713864ee5b69062ae14a6
https://doi.org/10.1158/2159-8290.22530542
https://doi.org/10.1158/2159-8290.22530542
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Top 200 genes by W2ndB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ea653bf1a57dc3586913496081fa16
https://doi.org/10.1158/2159-8290.22530548.v1
https://doi.org/10.1158/2159-8290.22530548.v1
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Supplementary Methods, Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289721a252634002833b734ca0a4dfa4
https://doi.org/10.1158/2159-8290.22530569.v1
https://doi.org/10.1158/2159-8290.22530569.v1
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Supplementary Figure S1. Generation of GEMM-derived cell lines. Supplementary Figure S2. QPCR and Western blot analyses of DTYMK expression in 634 cells upon indicated shDtymks transduction. Supplementary Figure S3. Lkb1-wt 634 and Lkb1-null t4 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265fb012de03c4fc4306ac7f9d34254d
https://doi.org/10.1158/2159-8290.22530572.v1
https://doi.org/10.1158/2159-8290.22530572.v1
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
Validation hits.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bceb37c821dcac8a1ab136c71799952
https://doi.org/10.1158/2159-8290.22530536.v1
https://doi.org/10.1158/2159-8290.22530536.v1
Autor:
Kwok-Kin Wong, Lewis C. Cantley, David E. Root, Nathanael S. Gray, Andrew L. Kung, William Y. Kim, David J. Kwiatkowski, John V. Heymach, Ignacio I. Wistuba, Don L. Gibbons, Lauren A. Byers, Alec Kimmelman, Ralph Scully, John M. Asara, Reuben J. Shaw, Brendan D. Manning, Jeffrey A. Engelman, Nabeel Bardeesy, Pasi A. Janne, Nirali M. Patel, D. Neil Hayes, Norman E. Sharpless, Sean T. Bailey, Jianming Zhang, Edward M. Driggers, Sung Choe, Xiaoxu Wang, Jeremy H. Tchaicha, Abigail B. Altabef, Zhao Chen, Yong Zhang, Peng Gao, Travis J. Cohoon, Chunxiao Xu, Thomas J.F. Nieland, Qingsong Liu, Julian Carretero, Glenn S. Cowley, Kevin Marks, Yan Liu
shRNAs used in manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c691f229fbdea7ae1eff6c9bde02817
https://doi.org/10.1158/2159-8290.22530533
https://doi.org/10.1158/2159-8290.22530533
Autor:
Nan Cao, Chen Dong, Sheng Ding, Yu Zhang, Katerina Akassoglou, Haixia Wang, Kelly M. Stewart, Xiaohu Wang, Min Xie, Dongwei Zhu, Ke Li, Jae K. Ryu, Edward M. Driggers, Tao Xu, Kai Liu, Saiyong Zhu, Tianhua Ma, Lu Ni
Publikováno v:
Nature. 548:228-233
Metabolism has been shown to integrate with epigenetics and transcription to modulate cell fate and function. Beyond meeting the bioenergetic and biosynthetic demands of T-cell differentiation, whether metabolism might control T-cell fate by an epige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f61e0d1fe52600b3de67a303abcf2de
https://doi.org/10.1038/nature23475
https://doi.org/10.1038/nature23475
Publikováno v:
Cell metabolism. 31(1)
Here, we explore the manipulation of immune cell metabolism as a strategy in target discovery and drug development for immune-mediated diseases. Comparing exploitation of metabolic pathways to kill tumor cells for cancer treatment with the reprogramm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ef922f0efde3940f5d746ea694a0fd
https://pubmed.ncbi.nlm.nih.gov/31839485
https://pubmed.ncbi.nlm.nih.gov/31839485