Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Edward M. Barnett"'
Autor:
Xudong Qiu, Seth T. Gammon, James R. Johnson, Federica Pisaneschi, Steven W. Millward, Edward M. Barnett, David Piwnica-Worms
Publikováno v:
Biosensors, Vol 12, Iss 9, p 693 (2022)
KcapTR488 is a dual-fluorophore peptide sensor for the real-time reporting of programmed cell death by fluorescence imaging. KcapTR488 contains a nuclear localization sequence (NLS) conjugated with Texas Red, a caspase-cleavable sequence (DEVD), and
Externí odkaz:
https://doaj.org/article/6393b174bd3545a69f429a9f8131334b
Autor:
Xudong Qiu, James R Johnson, Bradley S Wilson, Seth T Gammon, David Piwnica-Worms, Edward M Barnett
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88855 (2014)
Peptide probes for imaging retinal ganglion cell (RGC) apoptosis consist of a cell-penetrating peptide targeting moiety and a fluorophore-quencher pair flanking an effector caspase consensus sequence. Using ex vivo fluorescence imaging, we previously
Externí odkaz:
https://doaj.org/article/114ad8cb7a974869a1561cd5ed9c0868
Autor:
Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M Barnett, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9050 (2010)
BACKGROUND: Glaucoma is a leading cause of blindness worldwide. Nonetheless, the mechanism of its pathogenesis has not been well-elucidated, particularly at the molecular level, because of insufficient availability of experimental genetic animal mode
Externí odkaz:
https://doaj.org/article/db48dfa2c1194537b09fa71cc329f118
Autor:
Edward M. Barnett, Sidney T. Chang, Junqian Xu, Sheng-Kwei Song, Kathryn Trinkaus, Melike Pekmezci, Stella N. Arthur
Publikováno v:
Journal of glaucoma, vol 23, iss 8
PurposeTo evaluate optic nerve diffusion tensor imaging (DTI) parameters in glaucoma patients and controls, and to correlate DTI parameters with the rim area obtained with Heidelberg retina tomography (HRT) and with the severity of glaucomatous damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f0bb12d4e6b3a431185100a7db4696
https://doi.org/10.1097/ijg.0b013e318294861d
https://doi.org/10.1097/ijg.0b013e318294861d
Publikováno v:
Bioconjugate Chemistry. 23:1783-1793
Caspase-activatable cell-penetrating peptide (CPP) probes, designed for efficient cell uptake and specificity via cleavable intramolecular quenched-fluorophore strategies, show promise for identifying and imaging retinal ganglion cell apoptosis in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867c23a0b9797d08def024c36b627ebf
https://doi.org/10.1021/bc300036z
https://doi.org/10.1021/bc300036z
Publikováno v:
Proceedings of the National Academy of Sciences. 106:9391-9396
Molecular imaging probes have potential for in vivo identification of apoptosis and other intracellular processes. TcapQ, a cell-penetrating, near-infrared fluorescent peptide probe designed to be optically silent through intramolecular fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f184a827507bbc20047e06bb6026a3a
https://doi.org/10.1073/pnas.0812884106
https://doi.org/10.1073/pnas.0812884106
Publikováno v:
Bioconjugate Chemistry. 20:702-709
Apoptosis is required for normal cellular homeostasis, and deregulation of the apoptotic process is implicated in various diseases. Previously, we developed a cell-penetrating near-infrared fluorescence (NIRF) probe based on an activatable strategy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49a10d4faa66fed91a2da9c1599353c
https://doi.org/10.1021/bc800516n
https://doi.org/10.1021/bc800516n
Autor:
Fareed Hasan, Paul A. Knepper, M. J. Nolan, Leon W. Herndon, Robert Ritch, A.M. Miller, John R. Samples, R. Rand Allingham, Michael Giovingo, Regina Smolyak, Martin B. Wax, Jeffrey M. Liebmann, Robert D. Wertz, Edward M. Barnett
Publikováno v:
Journal of Glaucoma. 16:419-429
To correlate aqueous humor soluble CD44 (sCD44) concentration, visual field loss, and glaucoma risk factors in primary open-angle glaucoma (POAG) patients.Aqueous samples were obtained by paracentesis from normal and glaucoma patients who were underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5889ac875e090993d01a95d27e2143cc
https://doi.org/10.1097/ijg.0b013e318050ab4b
https://doi.org/10.1097/ijg.0b013e318050ab4b
Autor:
James R. Johnson, David Piwnica-Worms, Seth T. Gammon, Edward M. Barnett, Bradley Wilson, Xudong Qiu
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88855 (2014)
PLoS ONE
PLoS ONE
Peptide probes for imaging retinal ganglion cell (RGC) apoptosis consist of a cell-penetrating peptide targeting moiety and a fluorophore-quencher pair flanking an effector caspase consensus sequence. Using ex vivo fluorescence imaging, we previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f051c14287de69f225b8b67b21ed125
http://europepmc.org/articles/PMC3931650?pdf=render
http://europepmc.org/articles/PMC3931650?pdf=render
Publikováno v:
Immunity. 5:253-262
C57Bl/6 mice infected with mouse hepatitis virus, strain JHM (MHV-JHM) develop a chronic demyelinating encephalomyelitis. Infectious virus can be isolated only from symptomatic mice. In C57Bl/6 mice, two CD8+ T cell epitopes within the MHV-JHM surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026df511ed462e72a4c411bb31b092a3
https://doi.org/10.1016/s1074-7613(00)80320-9
https://doi.org/10.1016/s1074-7613(00)80320-9