Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Edward M Campbell"'
Autor:
Sarah Talley, Tyler Nguyen, Lily Van Ye, Rasa Valiauga, Jake DeCarlo, Jabra Mustafa, Benjamin Cook, Fletcher A. White, Edward M. Campbell
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Aging is associated with systemic chronic, low-grade inflammation, termed ‘inflammaging’. This pattern of inflammation is multifactorial and is driven by numerous inflammatory pathways, including the inflammasome. However, most studies t
Externí odkaz:
https://doaj.org/article/03c269e231da4bc2862c77acd286425d
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-14 (2023)
Abstract A severe complication of hematopoietic stem cell transplantation is graft-versus-host disease (GvHD), a reaction that occurs following the transfer of donor immune cells (the graft) into an allogeneic host. Transplanted cells recognize host
Externí odkaz:
https://doaj.org/article/85ad02c587d04006b7d73817c1d1aef6
Autor:
Tyler Nguyen, Natalie Nguyen, Ashlyn G. Cochran, Jared A. Smith, Mohammed Al-Juboori, Andrew Brumett, Saahil Saxena, Sarah Talley, Edward M. Campbell, Alexander G. Obukhov, Fletcher A. White
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Individuals who have experienced mild traumatic brain injuries (mTBIs) suffer from several comorbidities, including chronic pain. Despite extensive studies investigating the underlying mechanisms of mTBI-associated chronic pain, t
Externí odkaz:
https://doaj.org/article/82e6c3eeda304ff39cf7e974ecaf5bdf
Autor:
Sarah Talley, Rasa Valiauga, Lillian Anderson, Abigail R. Cannon, Mashkoor A. Choudhry, Edward M. Campbell
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Inflammatory bowel disease (IBD) is established to drive pathological sequelae in organ systems outside the intestine, including the central nervous system (CNS). Many patients exhibit cognitive deficits, particularly during disea
Externí odkaz:
https://doaj.org/article/1a0c1442c2bd412fa48af60fc7a37b7d
Autor:
Tyler Nguyen, Sarah Talley, Natalie Nguyen, Ashlyn G. Cochran, Mohammed Al-Juboori, Jared A. Smith, Saahil Saxena, Edward M. Campbell, Alexander G. Obukhov, Fletcher A. White
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 135-136 (2023)
OBJECTIVES/GOALS: Patients who have experienced conjunctive mild traumatic brain injuries (mTBIs) suffer from a number of comorbidities, including chronic pain. Despite extensive studies investigating the underlying mechanisms of mTBI-associated chro
Externí odkaz:
https://doaj.org/article/1bf6dc11398a482cbb0a252b52275ca9
Autor:
Kevin Burbidge, Virginia Zwikelmaier, Ben Cook, Michael M. Long, Barak Balva, Michael Lonigro, Grace Ispas, David J. Rademacher, Edward M. Campbell
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Extracellular vesicles (EVs) have been implicated in a wide variety of biological activities, have been implicated in the pathogenesis of numerous diseases, and have been proposed to serve as potential biomarkers of disease in human patients and anim
Externí odkaz:
https://doaj.org/article/4f7cf268e4a5457d9a3bfbe951b16303
Autor:
Sevnur Kömürlü, Margret Bradley, Nikolai Smolin, Sabrina Imam, Raymond F Pauszek, Seth L Robia, David Millar, Emi E Nakayama, Tatsuo Shioda, Edward M Campbell
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212888 (2019)
TRIM5α is an interferon inducible restriction factor which contributes to intrinsic defense against HIV infection by targeting the HIV capsid protein CA. Although human TRIM5α (huTRIM5α) does not potently inhibit HIV-1 infection, the ability of hu
Externí odkaz:
https://doaj.org/article/cb7efc497121450da84a870033e43ddf
Autor:
Marcin D Roganowicz, Sevnur Komurlu, Santanu Mukherjee, Jacek Plewka, Steven L Alam, Katarzyna A Skorupka, Yueping Wan, Damian Dawidowski, David S Cafiso, Barbie K Ganser-Pornillos, Edward M Campbell, Owen Pornillos
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006686 (2017)
Restriction factors are important components of intrinsic cellular defense mechanisms against viral pathogens. TRIM5α is a restriction factor that intercepts the incoming capsid cores of retroviruses such as HIV and provides an effective species-spe
Externí odkaz:
https://doaj.org/article/df135015d24340ad92100211730e0580
Publikováno v:
AIDS Res Hum Retroviruses
AIDS Research and Human Retroviruses
AIDS Research and Human Retroviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of COVID-19, a disease that as of July 10, 2020, has infected >12 million people and killed >500,000. COVID-19 infection leads to acute respiratory distress syndrome
Autor:
Adarsh Dharan, Edward M Campbell
Publikováno v:
Curr Opin Virol
A hallmark feature of lentiviruses, which separates them from other members of the retrovirus family, is their ability to infect non-dividing cells by traversing the nuclear pore complex. The viral determinant that mediates HIV-1 nuclear import is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a76e92ce3d1ae364aef2b9a157df6f
https://europepmc.org/articles/PMC9175559/
https://europepmc.org/articles/PMC9175559/