Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Edward L. Giovannucci"'
Autor:
Jie Chen, Xixian Ruan, Tian Fu, Shiyuan Lu, Dipender Gill, Zixuan He, Stephen Burgess, Edward L. Giovannucci, Susanna C. Larsson, Minzi Deng, Shuai Yuan, Xue Li
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105110- (2024)
Summary: Background: The causal associations of physical activity and sedentary behavior with the risk of gastrointestinal disease are unclear. We performed a Mendelian randomization analysis to examine these associations. Methods: Genetic instrument
Externí odkaz:
https://doaj.org/article/97a22ce0e17944c4be795341b78ddc86
Autor:
Yin Zhang, Qiao-Li Wang, Chen Yuan, Alice A. Lee, Ana Babic, Kimmie Ng, Kimberly Perez, Jonathan A. Nowak, Jesper Lagergren, Meir J. Stampfer, Edward L. Giovannucci, Chris Sander, Michael H. Rosenthal, Peter Kraft, Brian M. Wolpin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Patients with pancreatic ductal adenocarcinoma (PDAC) commonly develop symptoms and signs in the 1–2 years before diagnosis that can result in changes to medications. We investigate recent medication changes and PDAC diagnosis in Nurses’
Externí odkaz:
https://doaj.org/article/0a82e43a21c74225a3aed05fcc0b0536
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The relationship between body mass index (BMI) and body fatness could differ according to age, sex, and race-ethnicity. We aimed to evaluate in which contexts BMI could be a good measure for body fatness compared to dual-energy X-ray absorpt
Externí odkaz:
https://doaj.org/article/bbf0f7f9bb7843a4afdbabb85e6de78d
Autor:
Hongmei Zeng, Mengyuan Xu, Yingwei Xie, Sergiusz Nawrocki, Jakub Morze, Xianhui Ran, Tianhao Shan, Changfa Xia, Yixin Wang, Lingeng Lu, Xue Qin Yu, Catarina Machado Azeredo, John S. Ji, Xiaomei Yuan, Katherine Curi-Quinto, Yuexin Liu, Bingsheng Liu, Tao Wang, Hao Ping, Edward L. Giovannucci
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102138- (2023)
Summary: Background: Racial/ethnic disparities in prostate cancer are reported in the United States (US). However, long-term trends and contributors of racial/ethnic disparities in all-cause and cause-specific death among patients with prostate cance
Externí odkaz:
https://doaj.org/article/2146103436904266b2bb9d5bf0d0c1b5
Autor:
Mengyao Shi, Xiaoyu Zong, Jinhee Hur, Brenda M. Birmann, Otoniel Martinez-Maza, Marta Epeldegui, Andrew T. Chan, Edward L. Giovannucci, Yin Cao
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104566- (2023)
Summary: Background: Gut microbial dysbiosis contributes to colorectal cancer (CRC) pathogenesis, possibly mediated in part by increased intestinal permeability to endotoxin lipopolysaccharide (LPS), microbial translocation, and subsequent endotoxemi
Externí odkaz:
https://doaj.org/article/e9c3f15fadf84ca8a989ef59f19a7855
Autor:
Einar Stikbakke, Henrik Schirmer, Tore Knutsen, Martin Støyten, Tom Wilsgaard, Edward L. Giovannucci, Anne McTiernan, Anne E. Eggen, Hege S. Haugnes, Elin Richardsen, Inger Thune
Publikováno v:
Cancer Medicine, Vol 11, Iss 4, Pp 1005-1015 (2022)
Abstract Background Inflammation has been linked to prostate cancer and hypertension, but it remains equivocal whether elevated blood pressure (BP) influence prostate cancer risk and survival. Method Using Cox regression models, we examined the assoc
Externí odkaz:
https://doaj.org/article/6edb4ac2c1d34fef9f3fdbded8f072aa
Autor:
Zitong Li, Hanyu Chen, Cassandra D.L. Fritz, Xiaobin Zheng, Xiaoyu Zong, Katelin B. Nickel, Andrew Tipping, Long H. Nguyen, Andrew T. Chan, Edward L. Giovannucci, Graham A. Colditz, Margaret A. Olsen, Peter T. Campbell, Nicholas O. Davidson, Ryan C. Fields, Yin Cao
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 2, Pp 186-193 (2022)
Background and Aims: Early-onset colorectal cancer (CRC) is increasing in many developed countries. Type 2 diabetes mellitus has increased substantially in younger adults; however, its role in early-onset CRC remains unidentified. Methods: We conduct
Externí odkaz:
https://doaj.org/article/103fd8a9be5e4fc8b2e9e6f94c5b2e11
Autor:
Hongmei Zeng, Chen Yuan, Jakub Morze, Ruiying Fu, Kai Wang, Liang Wang, Feng Sun, John S. Ji, Edward L. Giovannucci, Mingyang Song
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104345- (2022)
Summary: Background: Limited data indicate that patients with colorectal cancer (CRC) are at higher risk of developing type 2 diabetes (T2D). We prospectively examined the risk of T2D between individuals with and without CRC in three large cohorts an
Externí odkaz:
https://doaj.org/article/9fc6290fd56d499880fbc6786114cdf5
Autor:
Tomotaka Ugai, Li Liu, Fred K. Tabung, Tsuyoshi Hamada, Benjamin W. Langworthy, Naohiko Akimoto, Koichiro Haruki, Yasutoshi Takashima, Kazuo Okadome, Hidetaka Kawamura, Melissa Zhao, Seyed Mostafa Mousavi Kahaki, Jonathan N. Glickman, Jochen K. Lennerz, Xuehong Zhang, Andrew T. Chan, Charles S. Fuchs, Mingyang Song, Molin Wang, Kun‐Hsing Yu, Marios Giannakis, Jonathan A. Nowak, Jeffrey A. Meyerhardt, Kana Wu, Shuji Ogino, Edward L. Giovannucci
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 11, Pp n/a-n/a (2022)
Abstract Background Certain dietary patterns can elicit systemic and intestinal inflammatory responses, which may influence adaptive anti‐tumor immune responses and tumor behavior. We hypothesized that pro‐inflammatory diets might be associated w
Externí odkaz:
https://doaj.org/article/62623fab877348ea82a5bb642d2684fe
Autor:
Dong Hoon Lee, Qi Jin, Ni Shi, Fenglei Wang, Alaina M. Bever, Jun Li, Liming Liang, Frank B. Hu, Mingyang Song, Oana A. Zeleznik, Xuehong Zhang, Amit Joshi, Kana Wu, Justin Y. Jeon, Jeffrey A. Meyerhardt, Andrew T. Chan, A. Heather Eliassen, Clary B. Clish, Steven K. Clinton, Edward L. Giovannucci, Fred K. Tabung
Publikováno v:
Metabolites, Vol 13, Iss 6, p 744 (2023)
The inflammatory and insulinemic potentials of diets have been associated with colorectal cancer risk. However, it is unknown whether the plasma metabolite profiles related to inflammatory diets, or to insulinemic diets, underlie this association. Th
Externí odkaz:
https://doaj.org/article/34123ceeec9e45459a6aadec9c90b2c0