Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Edward K Lobenhofer"'
Autor:
Andrey Alexeyenko, Deena M Wassenberg, Edward K Lobenhofer, Jerry Yen, Elwood Linney, Erik L L Sonnhammer, Joel N Meyer
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10465 (2010)
In order to generate hypotheses regarding the mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin) causes toxicity, we analyzed global gene expression changes in developing zebrafish embryos exposed to this potent toxicant in the context
Externí odkaz:
https://doaj.org/article/0bc1e0db326041e7a50bbe15e2c51614
Autor:
Marc A. Lafleur, Jonathan Werner, Madeline Fort, Edward K. Lobenhofer, Mercedesz Balazs, Ana Goyos
Publikováno v:
Journal of Immunotoxicology, Vol 17, Iss 1, Pp 110-121 (2020)
Mast cells play key roles in allergy, anaphylaxis/anaphylactoid reactions, and defense against pathogens/toxins. These cells contain cytoplasmic granules with a wide spectrum of pleotropic mediators that are released upon activation. While mast cell
Externí odkaz:
https://doaj.org/article/e894f9a9b3264041a061465abb107886
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Tissue expression datasets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca9c036ff650d951e09a23fd9df037d
https://doi.org/10.1158/1078-0432.22478721.v1
https://doi.org/10.1158/1078-0432.22478721.v1
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
File contains Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ab61e9ac692d080514ff0ca474deda
https://doi.org/10.1158/1078-0432.22478718
https://doi.org/10.1158/1078-0432.22478718
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Supplementary Figure 3 Evaluation of DLL3 expression in tumor types other than SCLC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b39bba8197b74f330bb0bf96836ca10
https://doi.org/10.1158/1078-0432.22478733
https://doi.org/10.1158/1078-0432.22478733
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Supplementary Figure 6 A, Expression of human CD25, CD69, PD-1, and 4-1BB on human CD4+ T cells isolated from mouse lungs harboring SHP-77 tumors 168 hours after treatment with AMG 757 or a control HLE BiTE® molecule. B, Expression of human CD25, CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fabaa475fbbbc60934a70c1f6051cd7
https://doi.org/10.1158/1078-0432.22478724.v1
https://doi.org/10.1158/1078-0432.22478724.v1
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Purpose:Small-cell lung cancer (SCLC) is an aggressive neuroendocrine tumor with a high relapse rate, limited therapeutic options, and poor prognosis. We investigated the antitumor activity of AMG 757, a half-life extended bispecific T-cell engager m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dea7869f950cb3f6173b8394654616e
https://doi.org/10.1158/1078-0432.c.6530028.v1
https://doi.org/10.1158/1078-0432.c.6530028.v1
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
This file contains Supplementary Tables 1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1913d46e2c693c8eafdefa39fa3c8b0a
https://doi.org/10.1158/1078-0432.22478715
https://doi.org/10.1158/1078-0432.22478715
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Supplementary Figure 1 DLL3 is differentially expressed in SCLC tumors and cell lines compared with normal tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00314926974585c9c925bea1763e6742
https://doi.org/10.1158/1078-0432.22478739
https://doi.org/10.1158/1078-0432.22478739
Autor:
Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin
Supplementary Figure 2 Representative photomicrographs of DLL3 immunostaining (brown color) in normal human tissues using immunohistochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461100ad3b39468bf2aae35f513e8116
https://doi.org/10.1158/1078-0432.22478736.v1
https://doi.org/10.1158/1078-0432.22478736.v1