Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Edward J. Thompson"'
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 63, Iss 2b, Pp 375-379 (2005)
We assessed the frequency of cerebrospinal fluid (CSF) restricted oligoclonal IgG bands (IgG-OCB) in Portuguese multiple sclerosis (MS) patients and its relationship with outcome. Paired CSF/serum samples of 406 patients with neurological disorders w
Externí odkaz:
https://doaj.org/article/e3d86a9416484ebf889599f49652cede
White matter abnormalities and dystonic motor disorder associated with mutations in the SLC16A2 gene
Autor:
Anthony J Hulse, Dragana Josifova, Heinz Jungbluth, Edward J. Thompson, Carsten G. Bönnemann, Meriel McEntagart, Artemis D. Gika, Samuel Refetoff, W. Jan, Ata Siddiqui, Selvakumari Edward, Tally Lerman-Sagie, James Drummond, Penny Fallon
Publikováno v:
Developmental Medicine & Child Neurology. 52:475-482
Aim Mutations in the SLC16A2 gene have been implicated in Allan–Herndon–Dudley syndrome (AHDS), an X-linked learning disability* syndrome associated with thyroid function test (TFT) abnormalities. Delayed myelination is a non-specific finding in
Autor:
Eduardo Tolosa, Olivier Rascol, Axel Petzold, Lars Rosengren, Nil Dizdar, Niall Quinn, Edward J. Thompson, Geoffrey Keir, Gregor K. Wenning, Björn Holmberg
Publikováno v:
Journal of the Neurological Sciences. 279:76-79
Background Two cerebrospinal fluid (CSF) biomarkers specific for neurodegeneration have recently emerged — the neurofilament light (NfL, 68 kDa) and heavy (NfH, 190–210 kDa) chains. This study investigated whether the CSF NfH and NfL levels or th
Autor:
Axel Petzold, Donna Grant, Djordje Gveric, Geoffrey Keir, M Groves, Klaus Schmierer, Miles D. Chapman, Louise Cuzner, Edward J. Thompson
Publikováno v:
Experimental Neurology
AimsAxonal pathology extends to the axonal cytoarchitecture leaving its signature on axoskeletal proteins. This study investigated whether neurofilament (NfH) phosphorylation would relate to the dynamics of axonal pathology in multiple sclerosis (MS)
Autor:
Gavin Giovannoni, Andrew J. Church, Russell C. Dale, Edward J. Thompson, Miles D. Chapman, Paul M. Candler
Publikováno v:
Journal of Neuroimmunology. 185:130-135
Three paired serial samples of CSF and serum (from days 8, 13 and 22) were taken from a patient referred to the National Hospital for Neurology and Neurosurgery with what was duly confirmed as having herpes simplex encephalitis using PCR. The samples
Publikováno v:
Medical Hypotheses. 68:113-124
The concept of experimental allergic encephalomyelitis (EAE) being linked to both rabies post-vaccination encephalomyelitis and multiple sclerosis (MS) has raised the intriguing question whether animal studies carried out for the induction and transm
Autor:
Andrew D. Kay, Mary Margaret Kerr, Edward J. Thompson, Geoffrey Keir, Axel Petzold, Martin D. Smith, Neil Kitchen
Publikováno v:
Journal of Neurotrauma. 23:1179-1184
Secondary ischaemic deficit adversely affects outcome in patients with subarachnoid hemorrhage (SAH). Astrocytes are vulnerable to ischemia, releasing glial fibrillary acidic protein (GFAP) when challenged. In this study, we followed nine patients wi
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 77:753-759
On the basis of preliminary evidence from patients with subarachnoid haemorrhage (SAH), axonal degeneration is thought to be an underestimated pathological feature.A longitudinal study in 17 patients with aneurysmal SAH. Ventricular CSF was collected
Publikováno v:
Journal of Immunological Methods. 310:62-66
We describe a semi-quantitative method for measuring the relative affinity of antigen-specific oligoclonal IgG bands separated by isoelectric focusing followed by blotting onto antigen-coated membrane and incubation with sodium thiocyanate. When the
Autor:
Martyn A. Sharpe, Konrad Rejdak, Geoff Keir, Mary Margaret Kerr, Axel Petzold, Edward J. Thompson, Gavin Giovannoni, Andrew D. Kay
Publikováno v:
Journal of the Neurological Sciences. 219:71-76
The findings of various studies reporting temporal changes in CSF total nitrite/nitrate (NOx) levels after subarachnoid hemorrhage (SAH) vary considerably. The study group comprised 10 patients with SAH and 10 control subjects. Total nitrite/nitrate