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pro vyhledávání: '"Edward J. Podlesny"'
Autor:
Nancy E. Lee, Donna R. Bramlett, Joanne T. Simmonds, William A. Kinney, Edward J. Podlesny, Dianne Kowal, Deanna T. Garrison, Rene P. Tasse, Ronald R. Notvest
Publikováno v:
Journal of Medicinal Chemistry. 35:4720-4726
In this report, a novel bioisostere of the alpha-amino acid, 3,4-diamino-3-cyclobutene-1,2-dione, has been incorporated into a series of compounds which are NMDA antagonists. These compounds, which are achiral and easily prepared, demonstrated good a