Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edward J. Needham"'
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Therapeutics for traumatic brains injuries constitute a global unmet medical need. Despite the advances in neurocritical care, which have dramatically improved the survival rate for the ~ 70 million patients annually, few treatments have bee
Externí odkaz:
https://doaj.org/article/15a3237dea7a4ab689ddbaf460c8c130
Autor:
Valerie Coppard, Grisha Szep, Zoya Georgieva, Sarah K. Howlett, Lorna B. Jarvis, Daniel B. Rainbow, Ondrej Suchanek, Edward J. Needham, Hani S. Mousa, David K. Menon, Felix Feyertag, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Joanne L. Jones
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
As the dimensionality, throughput and complexity of cytometry data increases, so does the demand for user-friendly, interactive analysis tools that leverage high-performance machine learning frameworks. Here we introduce FlowAtlas: an interactive web
Externí odkaz:
https://doaj.org/article/38abc65bbc2440418eb7722db7fcaa14
Autor:
Benedict D. Michael, Cordelia Dunai, Edward J. Needham, Kukatharmini Tharmaratnam, Robyn Williams, Yun Huang, Sarah A. Boardman, Jordan J. Clark, Parul Sharma, Krishanthi Subramaniam, Greta K. Wood, Ceryce Collie, Richard Digby, Alexander Ren, Emma Norton, Maya Leibowitz, Soraya Ebrahimi, Andrew Fower, Hannah Fox, Esteban Tato, Mark A. Ellul, Geraint Sunderland, Marie Held, Claire Hetherington, Franklyn N. Egbe, Alish Palmos, Kathy Stirrups, Alexander Grundmann, Anne-Cecile Chiollaz, Jean-Charles Sanchez, James P. Stewart, Michael Griffiths, Tom Solomon, Gerome Breen, Alasdair J. Coles, Nathalie Kingston, John R. Bradley, Patrick F. Chinnery, Jonathan Cavanagh, Sarosh R. Irani, Angela Vincent, J. Kenneth Baillie, Peter J. Openshaw, Malcolm G. Semple, ISARIC4C Investigators, COVID-CNS Consortium, Leonie S. Taams, David K. Menon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1–11 days pos
Externí odkaz:
https://doaj.org/article/b91096b3ed5a4dec92a987b9259afe0a
Autor:
Benedict D. Michael, Cordelia Dunai, Edward J. Needham, Kukatharmini Tharmaratnam, Robyn Williams, Yun Huang, Sarah A. Boardman, Jordan J. Clark, Parul Sharma, Krishanthi Subramaniam, Greta K. Wood, Ceryce Collie, Richard Digby, Alexander Ren, Emma Norton, Maya Leibowitz, Soraya Ebrahimi, Andrew Fower, Hannah Fox, Esteban Tato, Mark A. Ellul, Geraint Sunderland, Marie Held, Claire Hetherington, Franklyn N. Egbe, Alish Palmos, Kathy Stirrups, Alexander Grundmann, Anne-Cecile Chiollaz, Jean-Charles Sanchez, James P. Stewart, Michael Griffiths, Tom Solomon, Gerome Breen, Alasdair J. Coles, Nathalie Kingston, John R. Bradley, Patrick F. Chinnery, Jonathan Cavanagh, Sarosh R. Irani, Angela Vincent, J. Kenneth Baillie, Peter J. Openshaw, Malcolm G. Semple, ISARIC4C Investigators, COVID-CNS Consortium, Leonie S. Taams, David K. Menon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/153c2bbad3eb4cb580f29e9a39f7205b
Autor:
J. William L. Brown, Ferran Prados, Daniel R. Altmann, Baris Kanber, Jonathan Stutters, Nick G. Cunniffe, Joanne L. Jones, Zoya G. Georgieva, Edward J. Needham, Cyrus Daruwalla, Claudia Gandini Wheeler‐Kingshott, Peter Connick, Siddharthan Chandran, Robin Franklin, David MacManus, Rebecca Samson, Alasdair Coles, Declan Chard
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 10, Pp 1626-1642 (2022)
Abstract Objective In multiple sclerosis chronic demyelination is associated with axonal loss, and ultimately contributes to irreversible progressive disability. Enhancing remyelination may slow, or even reverse, disability. We recently trialled bexa
Externí odkaz:
https://doaj.org/article/1826f850492946098c69aca992564af5
Autor:
Alice Jacquens, Edward J. Needham, Elisa R. Zanier, Vincent Degos, Pierre Gressens, David Menon
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11193 (2022)
Head trauma is the most common cause of disability in young adults. Known as a silent epidemic, it can cause a mosaic of symptoms, whether neurological (sensory–motor deficits), psychiatric (depressive and anxiety symptoms), or somatic (vertigo, ti
Externí odkaz:
https://doaj.org/article/69b1345ccf094291ae41be2900e07c32
Ageing is associated with maladaptive immune response and worse outcome after traumatic brain injury
Autor:
Federico Moro, Francesca Pischiutta, Anaïs Portet, Edward J. Needham, Emma J. Norton, John R. Ferdinand, Gloria Vegliante, Eliana Sammali, Rosaria Pascente, Enrico Caruso, Edoardo Micotti, Daniele Tolomeo, Rafael di Marco Barros, Erik Fraunberger, Kevin K. W. Wang, Michael J. Esser, David K. Menon, Menna R. Clatworthy, Elisa R. Zanier
Traumatic brain injury is increasingly common in older individuals. Older age is one of the strongest predictors for poor prognosis after brain trauma, a phenomenon driven by the presence of extra-cranial comorbidities as well as pre-existent patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f0472bd63947fa3b30c5a52781162d
https://www.repository.cam.ac.uk/handle/1810/336645
https://www.repository.cam.ac.uk/handle/1810/336645