Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Edward J. Neafsey"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Externí odkaz:
https://doaj.org/article/720ce359753e44629b73d0f2241a972e
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 3, Pp 201-211 (2000)
Enzymatic β-carboline N-methyltransferase activities generate N-methylated β-carbolinium cations that are analogs of the parkinsonian-producing neurotoxin MPP+. We measured β-carboline-2N-methyltransferase and β-carboline-9N-methyltransferase act
Externí odkaz:
https://doaj.org/article/9fed7818268446559117bb50527fd487
Autor:
Edward J. Neafsey
Publikováno v:
Consciousness and cognition. 94
Is consciousness-the subjective awareness of the sensations, perceptions, beliefs, desires, and intentions of mental life-a genuine cause of human action or a mere impotent epiphenomenon accompanying the brain's physical activity but utterly incapabl
Autor:
Michael A. Collins, Nuzhath F. Tajuddin, Dimitrios E. Kouzoukas, Jennifer A. Schreiber, Hee-Yong Kim, Simon Kaja, Edward J. Neafsey
Publikováno v:
Neurochem Int
Chronic alcoholism promotes brain damage that impairs memory and cognition. High binge alcohol levels in adult rats also cause substantial neurodamage to memory-linked regions, notably, the hippocampus (HC) and entorhinal cortex (ECX). Concurrent wit
Autor:
Edward J. Neafsey, Michael A. Collins, Edward M. Campbell, Nuzhath F. Tajuddin, Robert M. Mitchell
Publikováno v:
Brain Research. 1642:163-169
Epidemiological studies indicate that light-moderate alcohol (ethanol) consumers tend to have reduced risks of cognitive impairment and progression to dementia during aging. Exploring possible mechanisms, we previously found that moderate ethanol pre
Publikováno v:
Neurotoxicity research. 34(3)
Preconditioning brain cultures with moderate concentrations of ethanol (EtOH) or trans-resveratrol (RES), key red wine constituents, can prevent amyloid-β (Aβ) neurotoxicity. Past studies have indicated that moderate EtOH activates synaptic N-methy
Autor:
Nuzhath F. Tajuddin, Kwan-Hoon Moon, Michael A. Collins, Hee-Yong Kim, James Brown, Edward J. Neafsey
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:161-169
Background Brain neurodamage from chronic binge ethanol (EtOH) exposure is linked to neuroinflammation and associated oxidative stress. Using rat organotypic hippocampal–entorhinal cortical (HEC) slice cultures of developing brain age, we reported
Autor:
Edward J. Neafsey, Michael A. Collins
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
It has been claimed over the years—most recently in this journal and several others—that neuronal degeneration in adult brain arising during chronic alcohol exposure is, or is likely to be, via “excitotoxicity” (Chandrasekar, 2013; Mehta et a
Publikováno v:
European Journal of Neuroscience. 32:1800-1812
Preconditioning rat hippocampal-entorhinocortical (HEC) slice or cerebellar cell cultures with moderate concentrations of ethanol (20-30 mm) neuroprotects against pro-inflammatory proteins such as HIV-1 glycoprotein 120 (gp120) or amyloid-β. The neu
Autor:
Mary O. Gray, Dipak K. Das, Edward J. Neafsey, Kenneth J. Mukamal, Dale A. Parks, Ronald J. Korthuis, Michael A. Collins
Publikováno v:
Alcoholism: Clinical and Experimental Research. 33:206-219
In contrast to many years of important research and clinical attention to the pathological effects of alcohol (ethanol) abuse, the past several decades have seen the publication of a number of peer-reviewed studies indicating the beneficial effects o