Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Edward J. Meehan"'
Autor:
Verdieck, Jim
Publikováno v:
American Scientist, 1983 Mar 01. 71(2), 213-213.
Externí odkaz:
https://www.jstor.org/stable/27851985
Autor:
Santhappa, M.
Publikováno v:
Current Science, 1955 Sep 01. 24(9), 321-321.
Externí odkaz:
https://www.jstor.org/stable/24055243
Autor:
Xiang Xu, Yuan Cai, Ying Wei, Fernando Donate, Jose Juarez, Graham Parry, Liqing Chen, Edward J Meehan, Richard W Ahn, Andrey Ugolkov, Oleksii Dubrovskyi, Thomas V O'Halloran, Mingdong Huang, Andrew P Mazar
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85349 (2014)
The urokinase plasminogen activator receptor (uPAR) plays a role in tumor progression and has been proposed as a target for the treatment of cancer. We recently described the development of a novel humanized monoclonal antibody that targets uPAR and
Externí odkaz:
https://doaj.org/article/0173507ab52c4bee81931476328e41db
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 4, Pp o651-o652 (2008)
The title compound, C16H14O7·H2O, possesses a planar three-ring skeleton; its carbonyl, one of the two hydroxy and two of the three methoxy O atoms and the water molecule form hydrogen bonds, giving rise to a layer structure.
Externí odkaz:
https://doaj.org/article/25a9816a26f54b7caf578d4658810604
Autor:
Liqing Chen, Zhuo Liu, Lin Lin, Bruce Furie, Gerry A. F. Nicolaes, Mingdong Huang, Barbara C. Furie, Edward J. Meehan, Cai Yuan
Publikováno v:
Journal of Biological Chemistry. 285:8824-8829
Factor VIII (FVIII) plays a critical role in blood coagulation by forming the tenase complex with factor IXa and calcium ions on a membrane surface containing negatively charged phospholipids. The tenase complex activates factor X during blood coagul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecdc4c32d06d88ea5deeb80f50eb0c8
https://doi.org/10.1074/jbc.m109.080168
https://doi.org/10.1074/jbc.m109.080168
Autor:
Randall C. Wilson, Ronny C. Hughes, Pamela D. Twigg, Justin W. Flatt, Edward J. Meehan, Joseph D. Ng
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:440-444
The ubiquitin-conjugating enzyme E2-25K has been identified as a huntingtin (the key protein in Huntington's disease) interacting protein and has been shown to play a role in mediating the toxicity of Abeta, the principal protein involved in Alzheime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce723ae2cbedfee18a6f43dd141095ca
https://doi.org/10.1107/s1744309109011117
https://doi.org/10.1107/s1744309109011117
Publikováno v:
Journal of Structural Biology. 162:40-49
3'-Azido-3'-deoxythymidine (AZT) is the first clinically effective drug for the treatment of human immunodeficiency virus infection. The drug interaction with human serum albumin (HSA) has been an important component in understanding its mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf6beb8edecb061bc3c1c36354c6208
https://doi.org/10.1016/j.jsb.2007.12.004
https://doi.org/10.1016/j.jsb.2007.12.004
Autor:
Liqing Chen, Xiaoyin E. Zhou, Brian A. Halloran, Yujun Wang, Mikhail Alexeyev, Edward J. Meehan, Nathan N. Aronson
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 70:243-251
Family 18 chitinases have the signature peptide DGXDXDXE forming the fourth beta-strand in the (beta/alpha)8-barrel of their catalytic domain. The carboxyl-end glutamic acid, E315 in Serratia marcescens chitinase A, serves as the acid/base during chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c033b3f8448a689b7aaa15cf98514f
https://doi.org/10.1271/bbb.70.243
https://doi.org/10.1271/bbb.70.243
Autor:
Edward J. Meehan, Liqing Chen, Xiaoyin E. Zhou, Dianna Toh, Thomas W. Hodge, Yujun Wang, Enrico L. DiGiammarino
Publikováno v:
Journal of Biological Chemistry. 279:40204-40208
Rab GTPases and their effectors facilitate vesicular transport by tethering donor vesicles to their respective target membranes. Rab9 mediates late endosome to trans-Golgi transport and has recently been found to be a key cellular component for human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5320a849c4cbc83e5eaccacc84b69c71
https://doi.org/10.1074/jbc.m407114200
https://doi.org/10.1074/jbc.m407114200
Autor:
Edward J. Meehan, Monika Reuter, Xiaoyin E. Zhou, Merlind Mücke, Liqing Chen, Yujun Wang, Detlev H. Krüger
Publikováno v:
Journal of Molecular Biology. 335:307-319
EcoRII is a type IIE restriction endonuclease that interacts with two copies of the DNA recognition sequence 5′CCWGG, one being the actual target of cleavage, the other serving as the allosteric effector. The mode of enzyme activation by effector b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9c77f9e14a51659884c73d87edb8cd
https://doi.org/10.1016/j.jmb.2003.10.030
https://doi.org/10.1016/j.jmb.2003.10.030