Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Edward J. McCLAIN"'
Autor:
Boyle C. Cheng, Isaac R. Swink, Cooper T. Cheng, Owen G. Corcoran, Vicki Z. Wang, Edward J. McClain, Praveer S. Vyas, Izzy Owen, Chen Xu, Daniel T. Altman, Alexander K. Yu
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 898 (2024)
P-15 is a 15-amino-acid-long biomimetic peptide widely demonstrated to enhance osteogenesis in vivo. Despite the prevalence of polyether-ether-ketone (PEEK) in interbody device manufacturing, a growing body of evidence suggests it may produce an unfa
Externí odkaz:
https://doaj.org/article/bf5cc3db2b224d8bb4bd052a137ca545
Autor:
Amol H. Trivedi, Vicki Z. Wang, Edward J. McClain, Praveer S. Vyas, Isaac R. Swink, Edward D. Snell, Boyle C. Cheng, Patrick J. DeMeo
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1544 (2024)
Musculoskeletal (MSK) pathology encompasses an array of conditions that can cause anything from mild discomfort to permanent injury. Their prevalence and impact on disability have sparked interest in more effective treatments, particularly within ort
Externí odkaz:
https://doaj.org/article/6323bb34bfab4bec875ce78b8f0ef1ae
Autor:
Longbo Li, Bianca Matsuo, Guillaume Levitre, Edward J. McClain, Eric A. Voight, Erika A. Crane, Gary A. Molander
Publikováno v:
Chemical Science. 14:2713-2720
Diverse DNA-encoded libraries of complex and novel sp3-rich spirocycles were achieved using a versatile and operationally simple visible light-mediated intermolecular [2 + 2] cycloaddition.
Autor:
Expédite Yen-Pon, Longbo Li, Guillaume Levitre, Jadab Majhi, Edward J. McClain, Eric A. Voight, Erika A. Crane, Gary A. Molander
Publikováno v:
Journal of the American Chemical Society. 144:12184-12191
DNA-encoded libraries have proven their tremendous value in the identification of new lead compounds for drug discovery. To access libraries in new chemical space, many methods have emerged to transpose traditional mol-scale reactivity to nmol-scale,
Autor:
Boyle C. Cheng, Isaac Swink, Edward J. McClain, Praveer S. Vyas, Thomas Muzzonigro, Jake Carbone, Ali Zaidi, Jason Long, Daniel T. Altman, Alexander K. Yu
Publikováno v:
Spine.
Publikováno v:
Chemical science. 13(41)
Recent advances in synthetic chemistry have seen a resurgence in the development of methods for visible light-mediated radical generation. Herein, we report the development of a photoactive ester based on a quinoline
Publikováno v:
ACS Catalysis. 10:12636-12641
Electron donor–acceptor (EDA) complexes can controllably generate radicals under mild conditions through selective photoexcitation events. However, unproductive reactivity from fast deactivation of...
Publikováno v:
Journal of the American Chemical Society. 141:8914-8920
This paper describes the one-electron interconversions of isolable NiIII and NiIV complexes through their reactions with carbon-centered radicals (R•). First, model NiIII complexes are shown to react with alkyl and aryl radicals to afford NiIV prod
Publikováno v:
Trends Chem
Over the past decade, photoredox catalysis has risen to the forefront of synthetic organic chemistry as an indispensable tool for selective small-molecule activation and chemical-bond formation. This cutting-edge platform allows photosensitizers to c
Electron donor-acceptor (EDA) complexes can controllably generate radicals under mild conditions through selective photoexcitation events. However, unproductive reactivity from fast deactivation of the photoexcited complexes through back electron tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969896c58bcc569b6265961fe22c3ab5
https://doi.org/10.26434/chemrxiv.12130011.v1
https://doi.org/10.26434/chemrxiv.12130011.v1