Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edward J. Manteufel"'
Autor:
Heather M. Dehlin, Edward J. Manteufel, Alexander Widiapradja, Bao Lu, Scott P. Levick, Lauren L. Kolb, Joseph S. Janicki, James R. Peña, Paul H. Goldspink, Amit Sharma, John D. Imig
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Cardiac fibrosis is an underlying cause of diastolic dysfunction, contributing to heart failure. Substance P (SP) activation of the neurokinin-1 receptor (NK-1R) contributes to cardiac fibrosis in hypertension. However, based on in vitro experiments,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776edef61f5a8335987be3341c4c3c2e
http://link.springer.com/article/10.1038/s41598-019-47369-0
http://link.springer.com/article/10.1038/s41598-019-47369-0
Autor:
Edward J. Manteufel, W. Gregory Hundley, Jianli Bi, Giselle C. Meléndez, David R. Soto-Pantoja, Scott P. Levick, Alexander Widiapradja, Tancia W. Bradshaw
Publikováno v:
Heart Lung Circ
Background Cancer patients receiving anthracycline-based chemotherapy (Anth-bC) may experience early cardiac fibrosis, which could be an important contributing mechanism to the development of impaired left ventricular (LV) function. Substance P, a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d624dc2c394b64bfdef044429f0224bc
https://pubmed.ncbi.nlm.nih.gov/30205930
https://pubmed.ncbi.nlm.nih.gov/30205930
Autor:
Christine Yu, Edward J. Manteufel, Lauren L. Kolb, Scott P. Levick, Gemma A. Figtree, Kristen J. Bubb, John D. Imig, Alexander Widiapradja
Publikováno v:
Cardiovascular Research. 114:S61-S61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::772652bd0236ed6c5aa87db5a0d5eced
https://doi.org/10.1093/cvr/cvy060.166
https://doi.org/10.1093/cvr/cvy060.166
Autor:
Heather M. Dehlin, Shaiban Jubair, Edward J. Manteufel, Scott P. Levick, Paul H. Goldspink, Jianping Li, Joseph S. Janicki
Accumulating evidence indicates that substance P is cardioprotective following ischemia-reperfusion primarily due to its potent coronary vasodilator actions. However, an anti-apoptotic effect of substance P has been observed in tenocytes following is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b72381b6042582ae3f326941b752c4
https://europepmc.org/articles/PMC4537946/
https://europepmc.org/articles/PMC4537946/
Autor:
Giselle C. Meléndez, Edward J. Manteufel, Scott P. Levick, Heather M. Dehlin, Thomas C. Register
Publikováno v:
Heart, lungcirculation. 24(4)
Background The sensory nerve neuropeptide substance P (SP) regulates cardiac fibrosis in rodents under pressure overload conditions. Interestingly, SP induces transient increased expression of specific genes in isolated rat cardiac fibroblasts, witho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d44e65be2718b128ccae2290cb649c
https://pubmed.ncbi.nlm.nih.gov/25550118
https://pubmed.ncbi.nlm.nih.gov/25550118
Publikováno v:
International journal of cardiology. 168(5)
Substance P is a sensory nerve neuropeptide located near coronary vessels in the heart. Therefore, substance P may be one of the first mediators released in the heart in response to hypertension, and can contribute to adverse myocardial remodeling vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058079969ce1170b51573814696fd2c8
https://pubmed.ncbi.nlm.nih.gov/23962787
https://pubmed.ncbi.nlm.nih.gov/23962787
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00f913177e066372cd5937ae5a4310c
https://doi.org/10.1096/fasebj.27.1_supplement.1129.2
https://doi.org/10.1096/fasebj.27.1_supplement.1129.2