Výsledky vyhledávání - "Edward J. Hornby"

Improved potency and specificity of Arg-Gly-Asp (RGD) containing peptides as fibrinogen receptor blocking drugs

Autor: Martyn R. Foster, Edward J. Hornby, Michael Menteith Hann, John Kitchin, P. Ward, Susan Brown

Publikováno v: Thrombosis research. 72(3)

A range of cyclic RGD based peptides have been developed to mimic the conformation of RGD within fibrinogen. These peptides, as well as echistatin (IC50 = 0.05 microM) and GRGDS (IC50 = 25 microM) fully inhibited adenosine diphosphate (ADP) (10 micro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cff1cbe39442115a993a7eaa126000
https://pubmed.ncbi.nlm.nih.gov/8303662

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Evidence that prostaglandin endoperoxides can induce platelet aggregation in the absence of thromboxane A2 production

Autor: Edward J. Hornby, Ian F. Skidmore

Publikováno v: Biochemical pharmacology. 31(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27df44419f91ece95dbd14d1ef495c6
https://pubmed.ncbi.nlm.nih.gov/7200773

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1-O-Hexadecyl-2-Acetyl-SN-3-Glycerophosphoryl- choline (PAF): Some Effects on the Aggregation of Human Platelets by Thrombin or Collagen

Autor: Edward J. Hornby, Colin R Perry

Publikováno v: Thrombosis and Haemostasis. 50:586-587

Summary1-O-hexadecyl-2-acetyl-sn-3-glycerophosphorylcholine (PAF) was examined as a potential mediator of aggregation induced by thrombin or high concentrations of collagen in indomethacin treated platelet rich plasma by investigating the response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bf0af253df88cbf4f79cd3aaa7894e4
https://doi.org/10.1055/s-0038-1665261

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