Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Edward J. Fuchs"'
Autor:
Sandra Abdul Massih, Mohamed G. Atta, Chloe L. Thio, Jeffrey A. Tornheim, Edward J. Fuchs, Rahul P. Bakshi, Mark A. Marzinke, Craig W. Hendrix, Ethel D. Weld
Publikováno v:
AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-7 (2024)
Abstract Introduction Peritoneal dialysis (PD) is an effective renal replacement modality in people with HIV (PWH) with end-stage kidney disease (ESKD), particularly those with residual kidney function. Data on pharmacokinetics (PK) of antiretroviral
Externí odkaz:
https://doaj.org/article/59cf5db24a5e45429f5b55b2e62a0c5b
Autor:
Peng Xiao, Sanjeev Gumber, Mark A. Marzinke, Thuy Hoang, Rohan Myers, Abhijit A. Date, Justin Hanes, Laura M. Ensign, Lin Wang, Lisa C. Rohan, Richard Cone, Edward J. Fuchs, Craig W. Hendrix, Francois Villinger
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
In spite of the rollout of oral pre-exposure prophylaxis (PrEP), the rate of new HIV infections remains a major health crisis. In the United States, new infections occur predominantly in men having sex with men (MSM) in rural settings where access to
Externí odkaz:
https://doaj.org/article/249879c852b34ff9a29c9654fd24b290
Autor:
Kevin DeLong, Sabrine Bensouda, Fareeha Zulfiqar, Hannah C. Zierden, Thuy M. Hoang, Alison G. Abraham, Jenell S. Coleman, Richard A. Cone, Patti E. Gravitt, Craig W. Hendrix, Edward J. Fuchs, Charlotte A. Gaydos, Ethel D. Weld, Laura M. Ensign
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The success of fecal microbiota transplant (FMT) in treating recurrent Clostridioides difficile infection has led to growing excitement about the potential of using transplanted human material as a therapy for a wide range of diseases and conditions
Externí odkaz:
https://doaj.org/article/fdea386915214f668e71e3f6716de0b1
Autor:
Jenell S, Coleman, Clarissa P, Diniz, Edward J, Fuchs, Mark A, Marzinke, Wutyi, Aung, Rahul P, Bakshi, Homayoon, Farzadegan, Jay H, Bream, Tricia L, Nilles, Sherry, Hudson, Namandjé N, Bumpus, George J, Schwartz, Michael A, Rosenblum, James F, Rooney, Craig W, Hendrix
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 92:89-96
Depot medroxyprogesterone acetate (DMPA) is a widely used contraceptive method. HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is highly effective in reducing HIV acquisition in women. We sought to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ac9fd31d7476d7fe8b5e7491f48c3e
https://doi.org/10.1097/qai.0000000000003113
https://doi.org/10.1097/qai.0000000000003113
Autor:
Adriana Andrade, Edward J. Fuchs, Mark A. Marzinke, Sandra Abdul Massih, Jennifer Breakey, Sasha Beselman, Ian McNicholl, Craig W. Hendrix
Publikováno v:
AIDS research and human retroviruses.
Medication adherence can be challenging for persons with difficulty swallowing tablets. We investigated the bioequivalence of a dissolved tablet when compared to a whole tablet of the fixed-dose combination elvitegravir (EVG)/cobicistat (COBI)/emtric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61c3693603761c92856412e0ebd93b3
https://pubmed.ncbi.nlm.nih.gov/36301928
https://pubmed.ncbi.nlm.nih.gov/36301928
Autor:
Asama Tanaudommongkon, Ayyappa Chaturvedula, Craig W. Hendrix, Edward J. Fuchs, Eugenie Shieh, Rahul P. Bakshi, Mark A. Marzinke
Publikováno v:
British journal of clinical pharmacology. 88(8)
Transgender women (TGW) have been underrepresented in trials and use gender-affirming hormonal therapies (GAHT) that may alter renal function by significantly increasing creatinine clearance. Population pharmacokinetic (popPK) models and simulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb65e796d7e87f787aa9fda04f9915f
https://pubmed.ncbi.nlm.nih.gov/35285974
https://pubmed.ncbi.nlm.nih.gov/35285974
Autor:
Anthony S. Ham, Karen W. Buckheit, Ethel D. Weld, Eugenie Shieh, Jennifer C. Breakey, Pamela Hummert, Mark A. Marzinke, Brian Caffo, Craig W. Hendrix, Robert W. Buckheit, Edward J. Fuchs, Amer Al-khouja, Huan Chen, Rahul P. Bakshi
Publikováno v:
AIDS Res Hum Retroviruses
A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e45e16087447a425cf4b0d732f46228
https://europepmc.org/articles/PMC8213010/
https://europepmc.org/articles/PMC8213010/
Autor:
Kelong Han, Kalpana Bakshi, William Spreen, Yu Lou, David A. Margolis, Craig W. Hendrix, Sharon A. Riddler, Edward J. Fuchs, Ronald D'Amico, Jafar Sadik Shaik, Susan L. Ford, Parul Patel, Stacey Edick, Ethel D. Weld, Mark A. Marzinke
Publikováno v:
British journal of clinical pharmacology. 88(4)
Aims Cabotegravir is an integrase strand transfer inhibitor in clinical development as long-acting (LA) injectable HIV preexposure prophylaxis. Methods This phase I study assessed pharmacokinetics of cabotegravir in plasma and anatomical sites associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd3854b0e21f12904c3e4aa98f12d3d
https://pubmed.ncbi.nlm.nih.gov/34240467
https://pubmed.ncbi.nlm.nih.gov/34240467
Autor:
Jafar Sadik Shaik, Valeriu Damian, Katarzyna J. Macura, Susan L. Ford, Paul Galette, Kalpana Bakshi, Craig W. Hendrix, Michael A. Jacobs, Meiyappan Solaiyappan, Robert L. Janiczek, Sarah Lee, Manish Gupta, William Spreen, Beat M. Jucker, Edward J. Fuchs, Kelong Han, Ethel D. Weld, Parul Patel, Ronald D'Amico, David A. Margolis
Publikováno v:
British journal of clinical pharmacology. 88(4)
Aim Cabotegravir long-acting (LA) intramuscular (IM) injection is being investigated for HIV preexposure prophylaxis due to its potent antiretroviral activity and infrequent dosing requirement. A subset of healthy adult volunteers participating in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365905f764b24bf4cc0ca8430b97f6df
https://pubmed.ncbi.nlm.nih.gov/35350084
https://pubmed.ncbi.nlm.nih.gov/35350084
Autor:
Caroline F. Zink, Jay J. Pillai, Eric Zimmerman, Daniel R. Weinberger, Mellissa Giegerich, Greer E. Prettyman, Molly Patricia O’Rourke, Marcus van Ginkel, Pamela Hummert, Jennifer C. Breakey, Kayla E. Carta, Edward J. Fuchs, Eesha Singh, Mark A. Marzinke, Craig W. Hendrix, Kristin L. Bigos
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-8 (2020)
Translational Psychiatry
Translational Psychiatry
The L-type calcium channel gene, CACNA1C, is a validated risk gene for schizophrenia and the target of calcium channel blockers. Carriers of the risk-associated genotype (rs1006737 A allele) have increased frontal cortical activity during working mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58f9ad76f9d57e9d3b94728043359b3
https://doi.org/10.1038/s41398-020-01066-z
https://doi.org/10.1038/s41398-020-01066-z