Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Edward J Michaud"'
Autor:
Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder
Publikováno v:
PLoS Genetics, Vol 1, Iss 4, p e53 (2005)
Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of developmental processes, such as left-right axis specification and limb and neural tube patterning. Genetic studies indicate t
Externí odkaz:
https://doaj.org/article/d545c2156a1947db8ae04099b6950a62
Autor:
Edward J. Michaud, Trenton R. Schoeb, Bradley K. Yoder, Jonathan M. Lehman, Yesim Aydin-Son, Michael K Miller
Publikováno v:
Developmental Dynamics. 237:1960-1971
The Oak Ridge Polycystic Kidney (ORPK) mouse was described nearly 14 years ago as a model for human recessive polycystic kidney disease. The ORPK mouse arose through integration of a transgene into an intron of the Ift88 gene resulting in a hypomorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4270ba1cc8230bd072b532d8352f12d0
https://doi.org/10.1002/dvdy.21515
https://doi.org/10.1002/dvdy.21515
Autor:
Bradley K. Yoder, Corey L. Williams, Edward J. Michaud, Jenny C. Schafer, Marlene E. Winkelbauer
Publikováno v:
Molecular Biology of the Cell. 19:2154-2168
Meckel-Gruber syndrome (MKS), nephronophthisis (NPHP), and Joubert syndrome (JBTS) are a group of heterogeneous cystic kidney disorders with partially overlapping loci. Many of the proteins associated with these diseases interact and localize to cili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07adfd0903adcc56626bc8092702116b
https://doi.org/10.1091/mbc.e07-10-1070
https://doi.org/10.1091/mbc.e07-10-1070
Autor:
Edward J. Michaud, Bradley K. Yoder
Publikováno v:
Cancer Research. 66:6463-6467
The primary cilium is a microtubule-based antenna-like structure that emanates from the surface of virtually all cells in the mammalian body. It is anchored to the cell by the basal body, which develops from the mother centriole of the centrosome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f14b8b1185549466b667f4e9e67756
https://doi.org/10.1158/0008-5472.can-06-0462
https://doi.org/10.1158/0008-5472.can-06-0462
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1447:107-112
A human homolog (RALY) of the mouse Raly gene was isolated and sequenced, and shown to encode a novel protein isoform containing a 16 amino acid in-frame insert in the variable region of the protein. Analysis of the corresponding region of the mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23c5a8ea46b50ecc21eef758999fecc
https://doi.org/10.1016/s0167-4781(99)00126-8
https://doi.org/10.1016/s0167-4781(99)00126-8
Autor:
Michael B. Zemel, Sue H. Kadwell, Edward J. Michaud, J. H. Kim, I R Patel, Richard P. Woychik, William O. Wilkison
Publikováno v:
Proceedings of the National Academy of Sciences. 92:4733-4737
Several dominant mutations at the agouti locus in the mouse cause a syndrome of marked obesity, hyperinsulinemia, and insulin resistance. Although it is known that the agouti gene is expressed in an ectopic manner in these mutants, the precise mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c27ac162131681524f97d84a2c94d4
https://doi.org/10.1073/pnas.92.11.4733
https://doi.org/10.1073/pnas.92.11.4733
Publikováno v:
Genes & Development. 7:1203-1213
Lethal yellow (Ay) is a mutation at the mouse agouti (a) locus that is associated with an all-yellow coat color, obesity, diabetes, tumors in heterozygotes, and preimplantation embryonic lethality in homozygotes. Previously, we cloned and characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d1c195a9fac71fdfc397398405e434
https://doi.org/10.1101/gad.7.7a.1203
https://doi.org/10.1101/gad.7.7a.1203
Autor:
John P. Sundberg, K. T. Cain, Edward J. Michaud, Brynn H. Voy, Donald A. Carpenter, Suchita Das, Yutao Liu
Publikováno v:
Veterinary pathology. 47(1)
Animal models carrying mutations in the hairless ( Hr) gene provide a rich resource for study of hair follicle biology. A spontaneous mouse mutant with a phenotype strikingly similar to rhino mutants of Hr arose spontaneously in the mouse facility at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefe1477d50a86008c34ceccb09715e7
https://pubmed.ncbi.nlm.nih.gov/20080498
https://pubmed.ncbi.nlm.nih.gov/20080498
Autor:
Edward J. Michaud, Viive M. Howell, Miriam H. Meisler, Cymbeline T. Culiat, Julie M. Jones, Sarah K. Bergren, Georgius de Haan, Wayne N. Frankel
Publikováno v:
Genetics. 180(3)
The auxiliary spliceosomal protein SCNM1 contributes to recognition of nonconsensus splice donor sites. SCNM1 was first identified as a modifier of the severity of a sodium channelopathy in the mouse. The most severely affected strain, C57BL/6J, carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f477a7afc4416d163c470ca4c9d36978
https://pubmed.ncbi.nlm.nih.gov/18791226
https://pubmed.ncbi.nlm.nih.gov/18791226
Autor:
John P. Sundberg, Patricia Soteropoulos, Mitchel J. Doktycz, Yutao Liu, Robert E. Olszewski, Cymbeline T. Culiat, Donald A. Carpenter, Brynn H. Voy, Xiaochen Liu, Edward J. Michaud, Suchita Das
Publikováno v:
The Journal of investigative dermatology. 127(7)
Near-naked hairless ( Hr N ) is a semi-dominant, spontaneous mutation that was suggested by allelism testing to be allelic with mouse Hairless ( Hr ). Hr N mice differ from other Hr mutants in that hair loss appears as the postnatal coat begins to em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc2bb64a0dde408ba6b79896f346505
https://pubmed.ncbi.nlm.nih.gov/17330134
https://pubmed.ncbi.nlm.nih.gov/17330134