Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Edward J Hsieh"'
Autor:
Xibei Dang, Lars Guelen, David Lutje Hulsik, Grigori Ermakov, Edward J. Hsieh, Joost Kreijtz, Judith Stammen-Vogelzangs, Imke Lodewijks, Astrid Bertens, Arne Bramer, Marco Guadagnoli, Alexis Nazabal, Andrea van Elsas, Thierry Fischmann, Veronica Juan, Amy Beebe, Maribel Beaumont, Hans van Eenennaam
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTMonoclonal antibodies have become an important class of therapeutics in the last 30 years. Because the mechanism of action of therapeutic antibodies is intimately linked to their binding epitopes, identification of the epitope of an antibody
Externí odkaz:
https://doaj.org/article/23e30f5d2f8c4516bac906e80f9ad9d7
Autor:
Judit Marsillach, Stephanie M Suzuki, Rebecca J Richter, Matthew G McDonald, Peter M Rademacher, Michael J MacCoss, Edward J Hsieh, Allan E Rettie, Clement E Furlong
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110054 (2014)
Homocysteinylation of lysine residues by homocysteine thiolactone (HCTL), a reactive homocysteine metabolite, results in protein aggregation and malfunction, and is a well-known risk factor for cardiovascular, autoimmune and neurological diseases. Hu
Externí odkaz:
https://doaj.org/article/1fb2e390fbb54bd099f64d51bb0122ba
Autor:
Nolan G. Ericson, Nathan Basisty, Vivian L. MacKay, Dao-Fu Dai, Edward J. Hsieh, Jason H. Bielas, David A. Crispin, Pabalu P. Karunadharma, Michael J. MacCoss, Ying A. Chiao, Richard P. Beyer, Peter S. Rabinovitch, Ellen Quarles
Publikováno v:
Aging Cell
Calorie restriction (CR) and rapamycin (RP) extend lifespan and improve health across model organisms. Both treatments inhibit mammalian target of rapamycin (mTOR) signaling, a conserved longevity pathway and a key regulator of protein homeostasis, y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e9639cbc4def019c1e2ccfcd1a54ed
https://doi.org/10.1111/acel.12317
https://doi.org/10.1111/acel.12317
Autor:
Haiwei Gu, Michael J. MacCoss, Danijel Djukovic, Nathan Basisty, David A. Crispin, Pabalu P. Karunadharma, Daniel Raftery, Peter S. Rabinovitch, Edward J. Hsieh, Tony Chen, Richard P. Beyer, Dao-Fu Dai, Ying A. Chiao
Publikováno v:
Aging Cell
Chronic caloric restriction (CR) and rapamycin inhibit the mechanistic target of rapamycin (mTOR) signaling, thereby regulating metabolism and suppressing protein synthesis. Caloric restriction or rapamycin extends murine lifespan and ameliorates man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c1fcaf7f9f0cfb0737ffd926304fb5
https://doi.org/10.1111/acel.12203
https://doi.org/10.1111/acel.12203
Autor:
Colleen K. Van Pelt, Edward J. Hsieh, Michael S. Bereman, Thomas N. Corso, Michael J. MacCoss
Publikováno v:
Molecular & Cellular Proteomics. 12:1701-1708
We report the development and characterization of a novel, vendor-neutral ultra-high pressure-compatible (∼10,000 p.s.i.) LC-MS source. This device is the first to make automated connections with user-packed capillary traps, columns, and capillary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7967d76e529e40e121576ddfc555b24
https://doi.org/10.1074/mcp.o112.024893
https://doi.org/10.1074/mcp.o112.024893
Autor:
Jarrett D. Egertson, Michael J. MacCoss, Michael S. Bereman, Edward J. Hsieh, Jimmy K. Eng, Gennifer E. Merrihew
Publikováno v:
Journal of the American Society for Mass Spectrometry. 23:2075-2082
We report an algorithm designed for the calibration of low resolution peptide mass spectra. Our algorithm is implemented in a program called FineTune which corrects systematic mass measurement error in one minute, with no input required besides the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f979ee3be569ebbedc05f5a8b65c3b9
https://doi.org/10.1007/s13361-012-0482-z
https://doi.org/10.1007/s13361-012-0482-z
Autor:
Edward J. Hsieh, UyenPhuong C. Tran, Jia Y. Chen, Catherine F. Clarke, Letian X. Xie, Shota Watanabe, Christopher M. Allan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1811:348-360
Coenzyme Q (ubiquinone or Q) is a lipid electron and proton carrier in the electron transport chain. In yeast Saccharomyces cerevisiae eleven genes, designated COQ1 through COQ9 , YAH1 and ARH1 , have been identified as being required for Q biosynthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd55f441d0ce7c84204551d6c9e338c1
https://doi.org/10.1016/j.bbalip.2011.01.009
https://doi.org/10.1016/j.bbalip.2011.01.009
Publikováno v:
Journal of Proteome Research. 9:1138-1143
In shotgun proteomics, the analysis of tandem mass spectrometry data from peptides can benefit greatly from high mass accuracy measurements. In this study, we have evaluated two database search strategies which use high mass accuracy measurements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf9e42889f223ed4666a5b1f1098a16
https://doi.org/10.1021/pr900816a
https://doi.org/10.1021/pr900816a
Publikováno v:
Biochemical and Biophysical Research Communications. 317:648-653
The Saccharomyces cerevisiae gene ABC1 was originally isolated as a multicopy suppressor of a yeast strain harboring a mutation in a cytochrome b translational activator (cbs2-223). Based on this identification, Abc1p was postulated to activate the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde3c4a730f6d475935153de9414265c
https://doi.org/10.1016/j.bbrc.2004.03.096
https://doi.org/10.1016/j.bbrc.2004.03.096
Autor:
Michael J. MacCoss, Allan E. Rettie, Rebecca J. Richter, Peter M. Rademacher, Stephanie M. Suzuki, Edward J. Hsieh, Judit Marsillach, Clement E. Furlong, Matthew G. McDonald
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e110054 (2014)
PLoS ONE, Vol 9, Iss 10, p e110054 (2014)
Homocysteinylation of lysine residues by homocysteine thiolactone (HCTL), a reactive homocysteine metabolite, results in protein aggregation and malfunction, and is a well-known risk factor for cardiovascular, autoimmune and neurological diseases. Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7c31822859f092804cf84c5ea35823
http://europepmc.org/articles/PMC4198189
http://europepmc.org/articles/PMC4198189