Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Edward J Farnell"'
Autor:
Nidhi Tyagi, Edward J Farnell, Colin M Fitzsimmons, Stephanie Ryan, Edridah Tukahebwa, Rick M Maizels, David W Dunne, Janet M Thornton, Nicholas Furnham
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004546 (2015)
Allergic reactions can be considered as maladaptive IgE immune responses towards environmental antigens. Intriguingly, these mechanisms are observed to be very similar to those implicated in the acquisition of an important degree of immunity against
Externí odkaz:
https://doaj.org/article/dd58467b718543aca24a62c32fee7896
Autor:
Ludovic Vallier, Sasha Mendjan, Alessandro Bertero, Igor Ruiz de los Mozos, Stephanie Brown, Hendrik G. Stunnenberg, Pedro Madrigal, An-Sofie Lenaerts, Nina C. Hubner, Daniel Ortmann, Christoph Yves Sadée, Shota Nakanoh, Edward J. Farnell, Anna Osnato, Rodrigo A. Grandy, Jernej Ule, Loukia Yiangou, Juned Kadiwala
Publikováno v:
Nature
Nature, 555, 7695, pp. 256-259
Nature, 555, 256-259
Nature, 555, 7695, pp. 256-259
Nature, 555, 256-259
The TGFβ pathway has essential roles in embryonic development, organ homeostasis, tissue repair and disease. These diverse effects are mediated through the intracellular effectors SMAD2 and SMAD3 (hereafter SMAD2/3), whose canonical function is to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947bcfa3e4d2b026f29ae8bdd4758cce
http://hdl.handle.net/2318/1804548
http://hdl.handle.net/2318/1804548
Publikováno v:
FEBS Letters. 587:3422-3427
The glycolytic enzyme triose phosphate isomerase from Schistosoma mansoni is a potential target for drugs and vaccines. Molecular modelling of the enzyme predicted that a Ser-Ala-Asp motif which is believed to be a helminth-specific epitope is expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3db915c22322b0c2d5ca64c052539b2
https://doi.org/10.1016/j.febslet.2013.09.022
https://doi.org/10.1016/j.febslet.2013.09.022
Publikováno v:
Fungal Biology
The ubiquitous filamentous fungus Aspergillus fumigatus secretes a number of allergens with protease activity and has been linked to a variety of allergic conditions such as Severe Asthma with Fungal Sensitization (SAFS) and Allergic Bronchopulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdaea2a9be5e5ee1f7ec2acd2f7d52a5
https://doi.org/10.1016/j.funbio.2012.07.004
https://doi.org/10.1016/j.funbio.2012.07.004
Autor:
Michael Bromley, Marcin G. Fraczek, Peter Warn, Sara Namvar, Sarah E. Herrick, Edward J. Farnell, Paul Bowyer
Publikováno v:
Namvar, S, Warn, P, Farnell, E, Bromley, M, Fraczek, M, Bowyer, P & Herrick, S 2015, ' Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model ', Clinical and Experimental Allergy, vol. 45, no. 5, pp. 982-993 . https://doi.org/10.1111/cea.12426
Namvar, S, Warn, P, Farnell, E, Bromley, M, Fraczek, M, Bowyer, P & Herrick, S 2015, ' Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model ', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, vol. 45, no. 5, pp. 982-993 . https://doi.org/10.1111/cea.12426, https://doi.org/10.1111/cea.12426
Namvar, S, Warn, P, Farnell, E, Bromley, M, Fraczek, M, Bowyer, P & Herrick, S 2015, ' Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model ', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, vol. 45, no. 5, pp. 982-993 . https://doi.org/10.1111/cea.12426, https://doi.org/10.1111/cea.12426
BACKGROUND: In susceptible individuals, exposure to Aspergillus fumigatus can lead to the development of atopic lung diseases such as allergic bronchopulmonary aspergillosis (ABPA) and severe asthma with fungal sensitization (SAFS). Protease allergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21143bde3702ae59c69d9e7cd648235
https://www.research.manchester.ac.uk/portal/en/publications/aspergillus-fumigatus-proteases-asp-f-5-and-asp-f-13-are-essential-for-airway-inflammation-and-remodelling-in-a-murine-inhalation-model(83718b5e-c784-4a66-bbd9-33212b0148c5).html
https://www.research.manchester.ac.uk/portal/en/publications/aspergillus-fumigatus-proteases-asp-f-5-and-asp-f-13-are-essential-for-airway-inflammation-and-remodelling-in-a-murine-inhalation-model(83718b5e-c784-4a66-bbd9-33212b0148c5).html