Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Edward J Cone"'
Autor:
E Dale Hart, Svante Vikingsson, Ruth E Winecker, Amy L Evans, Edward J Cone, John M Mitchell, Eugene D Hayes, Ronald R Flegel
Publikováno v:
Journal of Analytical Toxicology. 47:154-161
The purpose of this study was to compare results from five commercial hair testing laboratories conducting workplace drug testing with regard to bias, precision, selectivity and decontamination efficiency. Nine blind hair specimens, including cocaine
Autor:
Tory R. Spindle, Dennis J. Sholler, Edward J. Cone, Timothy P. Murphy, Mahmoud ElSohly, Ruth E. Winecker, Ronald R. Flegel, Marcel O. Bonn-Miller, Ryan Vandrey
Publikováno v:
JAMA network open. 5(7)
Products containing cannabinoids such as cannabidiol (CBD) have proliferated since 2018, when the Agriculture Improvement Act removed hemp (ie, cannabis containing0.3% Δ9-tetrahydrocannabinol [THC]) from the US controlled substances list. Topical ca
Autor:
Ruth E. Winecker, Elia Goffi, George E. Bigelow, Ryan Vandrey, John M. Mitchell, Ronald Flegel, Edward J. Cone, David J. Kuntz, Tory R. Spindle, Dennis J. Sholler
Publikováno v:
J Anal Toxicol
The market for products containing cannabidiol (CBD) is booming globally. However, the pharmacokinetics of CBD in different oral formulations and the impact of CBD use on urine drug testing outcomes for cannabis (e.g., 11-nor-9-carboxy-Δ9-tetrahydro
Autor:
Svante Vikingsson, Ruth E Winecker, Edward J Cone, David J Kuntz, Brian Dorsey, Martin Jacques, Melanie Senter, Ronald R Flegel, Eugene D Hayes
Publikováno v:
Journal of analytical toxicology. 46(8)
Given the recent popularity of cannabidiol (CBD) use and the emergence of ∆8-tetrahydrocannabinol (∆8-THC), the prevalence and concentrations of these and other cannabinoids were investigated in 2,000 regulated and 4,000 non-regulated specimens f
Autor:
Cecilia L Bergeria, Tory R Spindle, Edward J Cone, Dennis Sholler, Elia Goffi, John M Mitchell, Ruth E Winecker, George E Bigelow, Ronald Flegel, Ryan Vandrey
Publikováno v:
J Anal Toxicol
There is limited data on the comparative pharmacokinetics of cannabidiol (CBD) across oral and vaporized formulations. This within-subject, double-blind, double-dummy, placebo-controlled laboratory study analyzed the pharmacokinetic profile of CBD,
Autor:
August R. Buchhalter, Edward J. Cone, Lindsay P. Schwartz, Steven R. Hursh, Sidney H. Schnoll, Jack E. Henningfield, Reginald V. Fant, Peter G. Roma
Publikováno v:
Drug and Alcohol Dependence. 198:13-20
Introduction Behavioral economics provides a framework for quantifying drug abuse potential that can inform public health risk, clinical treatment, and research. Hypothetical purchase task (HPT) questionnaires may provide a low-cost and sensitive met
Autor:
Ronald Flegel, George E. Bigelow, John M. Mitchell, Evan S. Herrmann, Ryan Vandrey, Tory R. Spindle, Edward J. Cone, Charles LoDico
Publikováno v:
J Anal Toxicol
Oral cannabis products (a.k.a. “edibles”) have increased in popularity in recent years. Most prior controlled pharmacokinetic evaluations of cannabis have focused on smoked cannabis and included males who were frequent cannabis users. In this stu
Publikováno v:
Journal of Analytical Toxicology. 42:285-292
The pharmacokinetic profile of oral cocaine has not been fully characterized and prospective data on oral bioavailability are limited. A within-subject study was performed to characterize the bioavailability and pharmacokinetics of oral cocaine. Four
Autor:
Christopher Altomare, Edward J. Cone, August R. Buchhalter, Eric R. Kinzler, Anthony Costantino
Publikováno v:
Journal of Opioid Management. 13:441-448
The US Food and Drug Administration (FDA) considers the development of abuse-deterrent formulations of solid oral dosage forms a public health priority and has outlined a series of premarket studies that should be performed prior to submitting an app