Zobrazeno 1 - 10 of 130 pro vyhledávání: '"Edward J, Zuperku"'
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Akademický článek
Changes in pontine and preBötzinger/Bötzinger complex neuronal activity during remifentanil-induced respiratory depression in decerebrate dogs
Autor: Barbara Palkovic, Sanda Mustapic, Ivana Saric, Eckehard A. E. Stuth, Astrid G. Stucke, Edward J. Zuperku
Publikováno v: Frontiers in Physiology, Vol 14 (2023)
Introduction:In vivo studies using selective, localized opioid antagonist injections or localized opioid receptor deletion have identified that systemic opioids dose-dependently depress respiratory output through effects in multiple respiratory-relat
Externí odkaz: https://doaj.org/article/1903465c30534bc9ade77857ab3602fa
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3
Multi-Level Regulation of Opioid-Induced Respiratory Depression
Autor: Barbara Palkovic, Vitaliy Marchenko, Eckehard A. E. Stuth, Edward J. Zuperku, Astrid G. Stucke
Publikováno v: Physiology (Bethesda)
Opioids depress minute ventilation primarily by reducing respiratory rate. This results from direct effects on the preBötzinger Complex as well as from depression of the Parabrachial/Kölliker-Fuse Complex, which provides excitatory drive to preBöt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e474a7ede35e9b987b7da05758c8a13
https://doi.org/10.1152/physiol.00015.2020
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4
Dose-dependent Respiratory Depression by Remifentanil in the Rabbit Parabrachial Nucleus/Kölliker-Fuse Complex and Pre-Bötzinger Complex
Autor: Jennifer J. Callison, Edward J. Zuperku, Barbara Palkovic, Eckehard A. E. Stuth, Vitaliy Marchenko, Astrid G. Stucke
Publikováno v: Anesthesiology
Background Recent studies showed partial reversal of opioid-induced respiratory depression in the pre-Bötzinger complex and the parabrachial nucleus/Kölliker–Fuse complex. The hypothesis for this study was that opioid antagonism in the parabrachi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c973baa5c344f6238432297a3301baa
https://pubmed.ncbi.nlm.nih.gov/34352068
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Inputs to medullary respiratory neurons from a pontine subregion that controls breathing frequency
Autor: Edward J. Zuperku, Francis A. Hopp, Astrid G. Stucke, Eckehard A. E. Stuth, John G. Krolikowski, Jack Tomlinson
Publikováno v: Respiratory Physiology & Neurobiology. 265:127-140
Neurons in a subregion of the medial parabrachial (PB) complex control expiratory duration (TE) and the inspiratory on-switch. To better understanding the underlying mechanisms, this study aimed to determine the types of medullary neurons in the rhyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b817bd2e68f519f2f4259e3d9e5dcd8
https://doi.org/10.1016/j.resp.2018.06.011
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Endogenous glutamatergic inputs to the Parabrachial Nucleus/ Kölliker-Fuse Complex determine respiratory rate
Autor: Jennifer J. Callison, Edward J. Zuperku, Angela Navarrete-Opazo, Barbara Palkovic, Denise R. Cook-Snyder, Nicole McCarthy, Justin R. Miller, Astrid G. Stucke, Eckehard A. E. Stuth
Publikováno v: Respir Physiol Neurobiol
The Kolliker-Fuse Nucleus (KF) has been widely investigated for its contribution to "inspiratory off-switch" while more recent studies showed that activation of the Parabrachial Nucleus (PBN) shortened expiratory duration. This study used an adult, i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f19a1ce37672ee28e49da028ddf9cfa
https://europepmc.org/articles/PMC7309965/
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Interaction between the pulmonary stretch receptor and pontine control of expiratory duration
Autor: Astrid G. Stucke, Eckehard A. E. Stuth, Francis A. Hopp, Edward J. Zuperku
Publikováno v: Respir Physiol Neurobiol
Medial parabrachial nucleus (mPBN) neuronal activity plays a key role in controlling expiratory (E)-duration (TE). Pulmonary stretch receptor (PSR) activity during the E-phase prolongs TE. The aims of this study were to characterize the interaction b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fd4dd7699b295c07db2e89e461e0b9
https://doi.org/10.1016/j.resp.2021.103715
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Plný text Recenzováno Digitální knihovna AV ČR
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