Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Edward J, Dick"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
In-Jeong Kim, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Michael P. Tighe, Frank M. Szaba, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Lawrence L. Johnson, Amanda A. Schneck, Corinna N. Ross, Suzette D. Tardif, Donna Layne-Colon, Stephanie D. Mdaki, Edward J. Dick, Colin Chuba, Olga Gonzalez, Kathleen M. Brasky, John Dutton, Julienne N. Rutherford, Lark L. Coffey, Anil Singapuri, Claudia Sanchez San Martin, Charles Y. Chiu, Stephen J. Thomas, Kayvon Modjarrad, Jean L. Patterson, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Zika virus (ZIKV) is a mosquito-borne arbovirus that can cause severe congenital birth defects. The utmost goal of ZIKV vaccines is to prevent both maternal-fetal infection and congenital Zika syndrome. A Zika purified inactivated virus (ZPI
Externí odkaz:
https://doaj.org/article/83cd979680154fe68132d19796feb226
Autor:
Bindu Singh, Chivonne Moodley, Dhiraj K. Singh, Ruby A. Escobedo, Riti Sharan, Garima Arora, Shashank R. Ganatra, Vinay Shivanna, Olga Gonzalez, Shannan Hall-Ursone, Edward J. Dick Jr., Deepak Kaushal, Xavier Alvarez, Smriti Mehra
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
The expression of indoleamine 2,3-dioxygenase (IDO), a robust immunosuppressant, is significantly induced in macaque tuberculosis (TB) granulomas, where it is expressed on IFN-responsive macrophages and myeloid-derived suppressor cells. IDO expressio
Externí odkaz:
https://doaj.org/article/59e3a53626764aa2a1294a8cc4c559ab
Autor:
Riti Sharan, Shashank R. Ganatra, Dhiraj K. Singh, Journey Cole, Taylor W. Foreman, Rajesh Thippeshappa, Charles A. Peloquin, Vinay Shivanna, Olga Gonzalez, Cheryl L. Day, Neel R. Gandhi, Edward J. Dick Jr., Shannan Hall-Ursone, Smriti Mehra, Larry S. Schlesinger, Jyothi Rengarajan, Deepak Kaushal
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
A once-weekly oral dose of isoniazid and rifapentine for 3 months (3HP) is recommended by the CDC for treatment of latent tuberculosis infection (LTBI). The aim of this study is to assess 3HP-mediated clearance of M. tuberculosis bacteria in macaques
Externí odkaz:
https://doaj.org/article/659732e8266a421b8e6775d23db444b0
Autor:
Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here, the authors characterize tissue-level SARS-CoV-2 infection and pathogenesis in transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18 promoter (K18-hACE2) and show that infection induces lethality,
Externí odkaz:
https://doaj.org/article/36d6d32972464a4aafa1c9bc19844493
Autor:
Riti Sharan, Shashank R. Ganatra, Allison N. Bucsan, Journey Cole, Dhiraj K. Singh, Xavier Alvarez, Maya Gough, Cynthia Alvarez, Alyssa Blakley, Justin Ferdin, Rajesh Thippeshappa, Bindu Singh, Ruby Escobedo, Vinay Shivanna, Edward J. Dick Jr., Shannan Hall-Ursone, Shabaana A. Khader, Smriti Mehra, Jyothi Rengarajan, Deepak Kaushal
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Studies using the nonhuman primate model of Mycobacterium tuberculosis/simian immunodeficiency virus coinfection have revealed protective CD4+ T cell–independent immune responses that suppress latent tuberculosis infection (LTBI) reactivation. In p
Externí odkaz:
https://doaj.org/article/3b5a3287ec7841488006eb98b7de9d18
Autor:
In-Jeong Kim, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Michael P. Tighe, Frank M. Szaba, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Lawrence L. Johnson, Amanda A. Schneck, Corinna N. Ross, Suzette D. Tardif, Donna Layne-Colon, Stephanie D. Mdaki, Edward J. Dick, Colin Chuba, Olga Gonzalez, Kathleen M. Brasky, John Dutton, Julienne N. Rutherford, Lark L. Coffey, Anil Singapuri, Claudia Sanchez San Martin, Charles Y. Chiu, Stephen J. Thomas, Kayvon Modjarrad, Jean L. Patterson, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/04deac723e8743229172549357052591
Autor:
Renato Sathler-Avelar, Danielle Marquete Vitelli-Avelar, Armanda Moreira Mattoso-Barbosa, Marcelo Antônio Pascoal-Xavier, Silvana Maria Elói-Santos, Ismael Artur da Costa-Rocha, Andréa Teixeira-Carvalho, Edward J. Dick, Jane F. VandeBerg, John L. VandeBerg, Olindo Assis Martins-Filho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
We performed a detailed analysis of immunophenotypic features of circulating leukocytes and spleen cells from cynomolgus macaques that had been naturally infected with Trypanosoma cruzi, identifying their unique and shared characteristics in relation
Externí odkaz:
https://doaj.org/article/bff6ffc153a144eabe203b4c24792a8f
Autor:
Kathleen L. Vincent, Patrice A. Frost, Massoud Motamedi, Edward J. Dick, Jingna Wei, Jinping Yang, Robert White, Marie-Claire Gauduin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vaginal mucosal surfaces naturally offer some protection against sexually transmitted infections (STIs) including Human Immunodeficiency Virus-1, however topical preventative medications or vaccine designed to boost local immune responses can further
Externí odkaz:
https://doaj.org/article/094b31d980b0499697cce3d399fdba50
Autor:
Rebecca A. Porritt, Carol Chase Huizar, Edward J. Dick, Shyamesh Kumar, Renee Escalona, Angela C. Gomez, Stefani Marek-Iannucci, Magali Noval Rivas, Jean Patterson, Thomas G. Forsthuber, Moshe Arditi, Mark Gorelik
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectiveKawasaki disease (KD) is the most common cause of acquired pediatric heart disease in the developed world. 10% of KD patients are resistant to front-line therapy, and no interventions exist to address secondary complications such as myocardi
Externí odkaz:
https://doaj.org/article/01b14a3efd3f4042a8c41acfc5780ac6