Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Edward H. Lebetkin"'
Autor:
Fred B. Lih, Ling-Jen Chen Ferguson, Edward H. Lebetkin, Horace D. Parkinson, Kenneth B. Tomer, Leo T Burka, Susan J. Borghoff
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 70:1416-1423
Pulegone is a major constituent of pennyroyal oil and a minor component of peppermint oil. Pulegone is biotransformed to menthofuran and menthones (diastereomeric menthone and isomenthone) in pennyroyal and peppermint as well as in rodents. Pulegone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8ec7ea333b2b509b9775b6663dfa3f
https://doi.org/10.1080/15287390701382720
https://doi.org/10.1080/15287390701382720
Autor:
Molly Vallant, Gary A. Boorman, Diane F. Gerken, Edward H. Lebetkin, Leo T. Burka, Irwin D. Richard, Pamela E. Blackshear, Joel S. Parker, Edward K. Lobenhofer
Publikováno v:
Toxicologic Pathology. 33:111-117
The liver is a common organ for transcriptional profiling because of its role in xenobiotic metabolism and because hepatotoxicity is a common response to chemical exposure. To explore the impact that sampling different lobes may have on transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e321a4d4cc2aaa4b5de4d2e82cced4d5
https://doi.org/10.1080/01926230590522257
https://doi.org/10.1080/01926230590522257
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 65:2101-2118
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) is a mutagenic by-product of chlorination of drinking water, particularly where the water contains humic matter. MX has been estimated to account for 50% of the mutagenic activity in some drin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aab05b1921eb3208dad0db8d1806af
https://doi.org/10.1080/00984100290071522
https://doi.org/10.1080/00984100290071522
Autor:
Michael I. Luster, Thigpen Je, Ralph E. Wilson, Ann N. Tucker, Gary J. Rosenthal, Edward H. Lebetkin
Publikováno v:
Toxicology. 56(3)
Hepatic clearance is a major route of endotoxin detoxification. In the present study, the potential relationship between TCDD-induced endotoxin hypersensitivity and hepatotoxicity was examined. Acute doses of 50, 100, o 200 μg TCDD/kg body weight in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a38f739f4341c4c0d8fc3b22757534
https://pubmed.ncbi.nlm.nih.gov/2472021
https://pubmed.ncbi.nlm.nih.gov/2472021