Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Edward H Hellen"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62997 (2013)
We investigate the dynamics of a synthetic genetic repressilator with quorum sensing feedback. In a basic genetic ring oscillator network in which three genes inhibit each other in unidirectional manner, an additional quorum sensing feedback loop sti
Externí odkaz:
https://doaj.org/article/4577eba6a45b4fbfb614cb14112cc1d9
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76032 (2013)
We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and nu
Externí odkaz:
https://doaj.org/article/e4f2cb4ae8e645049dbaa7254bddb4ec
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23286 (2011)
An electronic analog of a synthetic genetic network known as the repressilator is proposed. The repressilator is a synthetic biological clock consisting of a cyclic inhibitory network of three negative regulatory genes which produces oscillations in
Externí odkaz:
https://doaj.org/article/b80b03de79934fcf8738aa72311bb3e6
Autor:
Edward H. Hellen, Evgeny Volkov
Publikováno v:
Chaos (Woodbury, N.Y.). 30(12)
The simplest ring oscillator is made from three strongly nonlinear elements repressing each other unidirectionally resulting in the emergence of a limit cycle. A popular implementation of this scheme uses repressive genes in bacteria creating the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb13cec87e80e47616ed106714747ac
https://pubmed.ncbi.nlm.nih.gov/33380051
https://pubmed.ncbi.nlm.nih.gov/33380051
Autor:
Edward H. Hellen, Evgeny Volkov
Publikováno v:
Chaos, Solitons & Fractals. 151:111176
There has long been interest in methods to achieve variability of collective modes in systems of coupled identical oscillators. Extensive multistability and a dynamically rich parameter space exist for two identical ring oscillators mean-field couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfb13ac665b7529d7acb7da26d496359
https://doi.org/10.1016/j.chaos.2021.111176
https://doi.org/10.1016/j.chaos.2021.111176
Publikováno v:
2019 3rd School on Dynamics of Complex Networks and their Application in Intellectual Robotics (DCNAIR).
We present a study of the formation of selforganized quasiperiodicity, as well as multistability in two dynamical systems of different nature. Multistability between torus and synchronized cycles is observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f287e464dfeb037ce65f6f04db59849e
https://doi.org/10.1109/dcnair.2019.8875600
https://doi.org/10.1109/dcnair.2019.8875600
Publikováno v:
Spectroscopic Membrane Probes ISBN: 9781351076791
Spectroscopic Membrane Probes
Spectroscopic Membrane Probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0cdc5d322ee7e11431d672d3871d1b
https://doi.org/10.1201/9781351076791-3
https://doi.org/10.1201/9781351076791-3
Autor:
Evgeny Volkov, Edward H. Hellen
We study the dynamical regimes demonstrated by a pair of identical 3-element ring oscillators (reduced version of synthetic 3-gene genetic Repressilator) coupled using the design of the "quorum sensing (QS)" process natural for interbacterial communi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a36d04b89386ba90cf403288d441ad
http://arxiv.org/abs/1712.04835
http://arxiv.org/abs/1712.04835
Electronic circuits are useful tools for studying potential dynamical behaviors of synthetic genetic networks. The circuit models are complementary to numerical simulations of the networks, especially providing a framework for verification of dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a20afc27cad2d52bdcfa1276c056e2
Autor:
Edward H. Hellen, Matthew J. Lanctot
Publikováno v:
American Journal of Physics. 75:326-330
We investigate a simple variation of the series RLC circuit in which anti-parallel diodes replace the resistor. This results in a damped harmonic oscillator with a nonlinear damping term that is maximal at zero current and decreases with an inverse c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0596ac0326d6857bd60a9984840b4fe3
https://doi.org/10.1119/1.2710481
https://doi.org/10.1119/1.2710481