Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Edward G. Rippie"'
Autor:
Edward G. Rippie, Derek V. Moe
Publikováno v:
Journal of Pharmaceutical Sciences. 86:26-32
A nondestructive procedure for determining anisotropy levels in compressed tablets was developed based on dynamic stress/strain measurements of viscoelasticity in the axial and radial directions. An instrument was designed and built capable of 10 nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386cdd16e5d6935f1a5959519d0d34e4
https://doi.org/10.1021/js960267p
https://doi.org/10.1021/js960267p
Autor:
Edward G. Rippie, Wei-Cheng Liaw
Publikováno v:
Pharmaceutical Development and Technology. 1:77-89
A mathematical model of mass transfer through a heterogeneous, multiphase barrier has been developed where the dispersed phase is capable of uptake of the diffusant according to a linear relationship. The model was used to describe the penetration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a3f698c82c4bed6a1f3900e9852b23
https://doi.org/10.3109/10837459609031421
https://doi.org/10.3109/10837459609031421
Autor:
William T. Morehead, Edward G. Rippie
Publikováno v:
Journal of Pharmaceutical Sciences. 83:708-715
The evolution of internal structure within compacts composed of selected drugs and direct compression excipients, occurring during the unloading phase of compaction, was studied in an instrumented rotary tablet press. Utilizing three‐dimensional vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43708a5411b56b117fff133b03249f82
https://doi.org/10.1002/jps.2600830523
https://doi.org/10.1002/jps.2600830523
Autor:
William T. Morehead, Edward G. Rippie
Publikováno v:
Journal of pharmaceutical sciences. 79(11)
The times of occurrence of maxima in punch stress, die-wall stress, and punch displacement in instrumented rotary tablet machines are shown to be noncoincidental for compacts exhibiting viscoelastic behavior. Equations are presented which characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f03b3ffe8a93a60112de67f5637a76
https://pubmed.ncbi.nlm.nih.gov/2127289
https://pubmed.ncbi.nlm.nih.gov/2127289
Autor:
Edward G. Rippie, Douglas W. Danielson
Publikováno v:
Journal of Pharmaceutical Sciences. 70:476-482
The processes of nonequilibrium generation and decay of axial and radial stresses within tablet compacts were analyzed in terms of three-dimensional linear viscoelastic theory. A rotary tablet press was instrumented to measure punch and die wall stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffed6a8eed52b53fd0d01543830adef
https://doi.org/10.1002/jps.2600700503
https://doi.org/10.1002/jps.2600700503
Publikováno v:
Journal of Pharmaceutical Sciences. 67:1121-1127
Methods for monitoring mechanical events occurring within particulate solids systems in a dynamic state are described. The electrical conductance and capacitance characteristics of such systems, as they relate to the degree of bed dilation or expansi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a6fcaf24a85b10ea42f6f1374a743b
https://doi.org/10.1002/jps.2600670825
https://doi.org/10.1002/jps.2600670825
Autor:
Jung Y. Park, Edward G. Rippie
Publikováno v:
Journal of Pharmaceutical Sciences. 66:858-861
Ultracentrifugation was used for the partial isolation of polysorbate 80 micelles in aqueous media to determine the apparent partition coefficients of various drug species between water and the micellar pseudophase. The ratio of solute concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be50fe7a4c206f7e6898f0f0c5a6d5d
https://doi.org/10.1002/jps.2600660631
https://doi.org/10.1002/jps.2600660631
Autor:
Takeru Higuchi, Edward G. Rippie
Publikováno v:
Journal of Pharmaceutical Sciences. 51:626-630
The rate of disappearance of the sulfhydryl groups of 2,3-dimercapto-1-propanol (BAL) in aqueous solutions in the presence of molecular oxygen and catalytic quantities of copper has been shown to depend directly on hydroxyl ion and BAL concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf01fb48dc70979935273e792cdf35d6
https://doi.org/10.1002/jps.2600510705
https://doi.org/10.1002/jps.2600510705
Autor:
Morris D. Faiman, Edward G. Rippie
Publikováno v:
Journal of Pharmaceutical Sciences. 54:719-722
Studies of the segregation behavior of particulate systems indicate the simultaneous occurrence of both segregation and mixing. The specific rate constants for these processes are calculated from statistical data and are shown to be a function of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a38bc6a5fcce86197e12add98853a84
https://doi.org/10.1002/jps.2600540512
https://doi.org/10.1002/jps.2600540512
Autor:
Takeru Higuchi, Edward G. Rippie
Publikováno v:
Journal of Pharmaceutical Sciences. 51:776-779
Autoxidation of BAL is shown to take place in the absence of metallic catalysts. Although the iodometric sulfhydryl concentration in this system was found to decrease linearly with time, the reaction was found to approach true zero order only at high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ea298b2cc953211ce858a7f2dd110c
https://doi.org/10.1002/jps.2600510818
https://doi.org/10.1002/jps.2600510818