Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Edward G. Niles"'
Publikováno v:
PLoS Pathogens, Vol 2, Iss 6, p e54 (2006)
Members of transforming growth factor-beta (TGF-beta) superfamily play pivotal roles in development in multicellular organisms. We report the functional characterization of the Schistosoma mansoni type II receptor (SmTbetaRII). Mining of the S. manso
Externí odkaz:
https://doaj.org/article/fdcda65c897f43b0945304b0100f3dbd
Autor:
Benjamin K. Dickerman, Linda Christen, Edward G. Niles, Mohamed R. Mohamed, Sarah C. Piacente
Publikováno v:
Virology. 376(1):211-224
Vaccinia virus early gene transcription requires the vaccinia termination factor, VTF, nucleoside triphosphate phosphohydrolase I, NPH I, ATP, the virion RNA polymerase, and the motif, UUUUUNU, in the nascent RNA, found within 30 to 50 bases from the
Autor:
Joelle M. Carlo, Edward G. Niles, Francisco Meirelles Bastos de Oliveira, Marcelo Rosado Fantappié, Philip T. LoVerde, Wenjie Wu, Ahmed Osman
Publikováno v:
FEBS Journal. 274:4075-4093
Smad proteins are the cellular mediators of the transforming growth factor-beta superfamily signals. Herein, we describe the isolation of a fourth Smad gene from the helminth Schistosoma mansoni, a receptor-regulated Smad (R-Smad) gene termed SmSmad1
Publikováno v:
Molecular and Biochemical Parasitology. 150:25-36
Fushi-tarazu factor-1 (FTZ-F1) is an orphan nuclear receptor involved in gene regulation of various developmental processes and physiological activities. We identified a new member of ftz-f1 gene in Schistosoma mansoni, termed Smftz-f1alpha. The Smft
Publikováno v:
Molecular and Biochemical Parasitology. 148:31-43
Full length cDNA clones encoding a Schistosoma mansoni homologue of vertebrate CAR/PXR/VDR group nuclear receptor, termed SmCAR were isolated from screening a S. mansoni adult worm cDNA library. SmCAR is a 702 amino acid protein which retains a typic
Autor:
Edward G. Niles, Mohamed R. Mohamed
Publikováno v:
Virology. 324(2):493-500
Recent results from this laboratory demonstrated the ability of U5NU-containing oligonucleotides to stimulate premature termination of early gene transcription in vitro. Further studies on the oligonucleotide sequence and structural requirements for
Publikováno v:
Canadian Journal of Zoology. 82:357-374
Schistosome parasites are muticellular eucaryotic organisms with a complex life cycle that involves mammalian and snail hosts. Unlike other trematode parasites, schistosomes (along with the Didymozoidae) have evolved separate sexes or dioecy. Sex is
Publikováno v:
Vaccine. 22:130-136
Protection against Schistosoma mansoni infection in C57BL/6 female mice was evaluated by two DNA vaccination strategies. Mice were either vaccinated by intramuscular injection with pcDNAI/Amp constructs encoding either Cu/Zn cytosolic superoxide dism
Autor:
Mohamed R. Mohamed, Edward G. Niles
Publikováno v:
Journal of Biological Chemistry. 278:39534-39541
Vaccinia virus early genes are unique in that transcription terminates in a signal- and factor-dependent manner. Recent results from this laboratory demonstrated that a 22-mer RNA oligonucleotide containing a central U9 sequence exhibited sequence- a
Publikováno v:
Molecular and Biochemical Parasitology. 131:45-54
Drosophila (SINA) and human Seven in Absentia (SIAH-1 and SIAH-2) have been implicated in ubiquitin-mediated proteolysis of different target proteins. Using the Schistosoma mansoni nuclear receptor SmRXR2 as bait in a yeast two-hybrid system, we iden