Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Edward F. Labelle"'
Autor:
Thomas N. Tulenko, Kathy Boeze-Battaglia, R. Preston Mason, G. Stephen Tint, Robert D. Steiner, William E. Connor, Edward F. Labelle
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 134-143 (2006)
The Smith-Lemli-Opitz syndrome (SLOS) is an often lethal birth defect resulting from mutations in the gene responsible for the synthesis of the enzyme 3β-hydroxy-steroid-Δ7-reductase, which catalyzes the reduction of the double bond at carbon 7 on
Externí odkaz:
https://doaj.org/article/c28f947ab933436e8df292ea5241847b
Autor:
William E. Connor, Edward F. LaBelle, R. Preston Mason, G. Stephen Tint, Robert D. Steiner, Thomas N. Tulenko, Kathy Boeze-Battaglia
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 134-143 (2006)
The Smith-Lemli-Opitz syndrome (SLOS) is an often lethal birth defect resulting from mutations in the gene responsible for the synthesis of the enzyme 3beta-hydroxy-steroid-Delta7-reductase, which catalyzes the reduction of the double bond at carbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0daed04717aebf557437e9eb28ede9
http://www.sciencedirect.com/science/article/pii/S0022227520336634
http://www.sciencedirect.com/science/article/pii/S0022227520336634
Publikováno v:
Journal of Cellular Physiology. 209:405-412
Spermine (SPM) and spermidine (SPD) activate isolated phosphatidylinositol-4-phosphate 5-kinases (PI(4)P5K), enzymes that convert phosphatidylinositol-4-phosphate to phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). PI(4,5)P2 formation is known to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf3bbdcd198589bb66fee79ba60f807
https://doi.org/10.1002/jcp.20729
https://doi.org/10.1002/jcp.20729
Autor:
Daniel P. Delaney, Edward F. LaBelle, Alan J. Wein, Samuel Chacko, Stephen A. Zderic, Joseph A. Hypolite
Publikováno v:
Neurourology and Urodynamics. 25:179-184
Aims Hypertrophy of the urinary bladder smooth muscle (detrusor) is associated with partial bladder outlet obstruction (PBOO). Hypertrophied detrusor smooth muscle (DSM) reveals altered contractile characteristics. In this study, we analyzed the lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24daf193164be462360f6561571aa4ad
https://doi.org/10.1002/nau.20214
https://doi.org/10.1002/nau.20214
Autor:
Edward F. LaBelle, Cyril M. Pilane
Publikováno v:
Journal of Cellular Physiology. 199:310-315
We have shown previously that nitric-oxide (NO) can induce apoptosis of vascular smooth muscle cells (VSMCs) and that the NO-induced apoptosis is accompanied by an increase in arachidonic acid release via cytoplasmic Ca(2+)-dependent phospholipase A(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87323ae43e9c081a5e7c7566c5c7cc1
https://doi.org/10.1002/jcp.10464
https://doi.org/10.1002/jcp.10464
Autor:
Edward F. LaBelle, Cyril M. Pilane
Publikováno v:
Journal of Cellular Physiology. 198:48-52
Apoptosis of vascular smooth muscle cells (VSMCs) has recently drawn a lot of interest in various laboratories due to its importance in atherogenesis. We have shown previously that nitric-oxide (NO) can induce apoptosis of VSMCs and that the NO-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c5f6a894cdba21a9a977313f156ea3
https://doi.org/10.1002/jcp.10382
https://doi.org/10.1002/jcp.10382
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1583:273-278
The phospholipase C (PLC) isoform most important during agonist-activated IP(3) production in vascular smooth muscle is still unknown. When PLC activity in rat tail artery homogenate was determined, this activity was shown to be inhibited by an antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1fbf55fa77ff6aa3609defd4cfbb49
https://doi.org/10.1016/s1388-1981(02)00218-4
https://doi.org/10.1016/s1388-1981(02)00218-4
Autor:
Erzsebet Polyak, Edward F. LaBelle
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C1129-C1137
The mechanism of agonist-activated arachidonate release was studied in segments of rat tail artery. Tail artery segments were prelabeled with [3H]arachidonate and then stimulated with norepinephrine (NE), and the radioactivity of the extracellular me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7000db790589fb99a2d592c98bbea7d
https://doi.org/10.1152/ajpcell.1998.274.4.c1129
https://doi.org/10.1152/ajpcell.1998.274.4.c1129
Publikováno v:
Journal of Cellular Physiology. 171:271-283
About 25% of the total cellular PLC beta 2 content was found to be associated with a sarcolemmal fraction (SARC) isolated from unstimulated porcine trachealis smooth muscle. SARC-associated PLC beta 2 was located within two compartments, a detergent-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f8151df6b2c401091831b36065528b
https://doi.org/10.1002/(sici)1097-4652(199706)171:3<271::aid-jcp5>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199706)171:3<271::aid-jcp5>3.0.co
Autor:
Erzsébet Polyák, Edward F. Labelle
Publikováno v:
Journal of Cellular Physiology. 169:358-363
Receptor-mediated inositol 1,4,5-trisphosphate formation in most tissue is dependent on a variety of phospholipase C isoforms. To determine which phospholipase C isoforms were present in vascular smooth muscle compared to brain, liver, and spleen, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8a5f7a83a5cac4c351e849f64905df
https://doi.org/10.1002/(sici)1097-4652(199611)169:2<358::aid-jcp15>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199611)169:2<358::aid-jcp15>3.0.co