Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Edward E. Soltis"'
Autor:
Edward E. Soltis, Jacob D. Peuler, Hassan Y. Zammam, James R. Sowers, Mahmoud Bourghli, John A. Miller
Publikováno v:
Metabolism. 46:1199-1205
Type II diabetic patients and others with insulin resistance are at risk for development of hypertension characterized by elevated peripheral vascular resistance and loss of insulin's normal vasodilating activity. Oral antidiabetic drugs have recentl
Publikováno v:
Clinical and Experimental Hypertension. 19:297-312
This study examined the temporal effects of the polyamine synthesis inhibitor eflornithine (alpha-difluoromethylornithine) on vascular responses to KCI, norepinephrine, sodium nitroprusside and acetylcholine in aortic rings from coarctation hypertens
Publikováno v:
Clinical and Experimental Hypertension. 16:595-610
This study was performed to assess the potential role of polyamines in the alterations in vascular structure and function in spontaneously hypertensive rats (SHR). The effects of chronic administration of eflornithine (alpha-difluoromethylornithine;
Publikováno v:
Pharmaceutical Research. 11:1211-1215
Publikováno v:
Clinical and Experimental Hypertension. 15:171-184
The effects of in vivo treatment with the nonpeptide subtype 1 angiotensin II receptor antagonist, losartan, on blood pressure and vascular reactivity in normotensive male Sprague-Dawley rats were studied. Initial acute experiments demonstrated that
Publikováno v:
Developmental Pharmacology and Therapeutics. 20:107-110
The chronic effects of short-term administration of a high salt diet to postweaning rats on blood pressure (BP) was studied. BP was significantly elevated following 4 weeks of treatment. After stopping the high salt diet, BP dropped to control levels
Publikováno v:
Life Sciences. 53:PL303-PL307
Numerous studies have been reported examining the effects of antihypertensive treatment on peripheral vascular responsiveness in spontaneously hypertensive rats (SHR). This study was conducted to determine the effects of chronic treatment with 2 anti
Autor:
Pamela S. Newman, Edward E. Soltis
Publikováno v:
Developmental Pharmacology and Therapeutics. 18:44-54
This study investigated the ontogeny of contractile and relaxation responses in aortic and tail artery preparations from 3-, 7-, and 11-week-old male Sprague-Dawley rats. Contractile responses to norepinephrine, serotonin, KCl, electrical stimulation
Publikováno v:
Hypertension. 18:85-92
This study was performed to determine if an alteration in vascular polyamine contents is associated with the development of deoxycorticosterone acetate-salt hypertension. The effects of chronic administration of alpha-difluoromethylornithine, a speci
Publikováno v:
European Journal of Pharmacology. 199:279-289
Ligand binding studies with WB 4101 revealed that the rat aorta contains both the alpha 1a- and alpha 1b-adrenoceptor subtypes. Results obtained following treatment with the irreversible antagonists phenoxybenzamine, chlorethylclonidine or SZL-49 (4-