Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Edward E Tredget"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123054 (2015)
Hypertrophic scarring is a frequent fibroproliferative complication following deep dermal burns leading to impaired function and lifelong disfigurement. Decorin reduces fibrosis and induces regeneration in many tissues, and is significantly downregul
Externí odkaz:
https://doaj.org/article/0f4bbbe28b0141fe8ec146b9f726a7ad
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7119 (2009)
Studies have shown that allogeneic (allo-) bone marrow derived mesenchymal stem cells (BM-MSCs) may enhance tissue repair/regeneration. However, recent studies suggest that immune rejection may occur to allo-MSCs leading to reduced engraftment. In th
Externí odkaz:
https://doaj.org/article/aeff17a586a94a38b1554c959cdc2add
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1886 (2008)
Bone marrow derived mesenchymal stem cells (BM-MSCs) have been shown to enhance wound healing; however, the mechanisms involved are barely understood. In this study, we examined paracrine factors released by BM-MSCs and their effects on the cells par
Externí odkaz:
https://doaj.org/article/6b6f2edcba8b4e85983c024338f231bd
Publikováno v:
European Burn Journal, Vol 4, Iss 2, Pp 248-258 (2023)
Background: Recent advances in burn care have significantly improved the survival rate of patients with extensive burn injuries, placing greater emphasis on reconstruction to improve the long-term outcomes of scar deformities. Anterior and lateral ne
Externí odkaz:
https://doaj.org/article/319cf77f271d4678964510cc8b1ecab6
Autor:
Guang Yang, Haiyan Chen, Qun Chen, Jiayi Qiu, Mulan Qahar, Zhimeng Fan, Weiwei Chu, Edward E. Tredget, Yaojiong Wu
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-18 (2023)
Abstract Background The hair follicles (HFs) are barely regenerated after loss in injuries in mammals as well as in human beings. Recent studies have shown that the regenerative ability of HFs is age-related; however, the relationship between this ph
Externí odkaz:
https://doaj.org/article/7556e82bc33d4ba9a9e34b61d6f1f13d
Autor:
Stephanie Schetzsle, Weber Wei Chiang Lin, Prabhu Purushothaman, Jie Ding, Peter Kwan, Edward E Tredget
Publikováno v:
Journal of Burn Care & Research.
Guidelines and protocols for orthoses in burn scar contracture rehabilitation are limited. The current study aims to determine the optimal frequency of casting, potentially facilitating the development of a serial casting protocol. Previous literatur
Publikováno v:
Advances in Wound Care. 11:234-254
Significance: Hypertrophic scars (HTS) are a fibroproliferative disorder that occur following deep dermal injury and affect up to 72% of burn patients. These scars result in discomfort, impaired mobility, disruption of normal function and cosmesis, a
Autor:
Julie A Rizzo, Sandra L. Taylor, Rajiv Sood, Angela Gibson, Robert Cartotto, M. A. Marano, Giavonni M. Lewis, Edward E. Tredget, Jeffrey R. Fine, Carlos J. Jimenez, Herbert Phelan, James H. Holmes, Kevin N Foster, Sarah Fischer, Ariel M. Aballay, David T. Hill, Lucy Wibbenmeyer, David J. Smith, Mark R. Hemmila, Anjay Khandelwal, David G. Greenhalgh, Anthony Baldea, Jeremy Goverman
Publikováno v:
Annals of surgery.
Objectives ABRUPT was a prospective, non-interventional, observational study of resuscitation practices at 21 burn centers. The primary goal was to examine burn resuscitation with albumin or crystalloids alone, in order to design a future prospective
Reduced Intraoperative Blood Loss and Hypothermia in Burn Surgery using Cardiopulmonary Bypass Pumps
Publikováno v:
Plastic Surgery. 31:9-16
Objective: Patients presenting with total body surface area (TBSA) >40% burns require significant surgical treatment. Two substantial challenges during these surgeries are limiting blood loss and maintaining core temperatures. To overcome these chall
Publikováno v:
Wound Repair and Regeneration. 29:810-819
Hypertrophic scars (HTS) are a common complication following burn injuries with prolonged inflammation. They do not respond well to current treatment options including mechanical, biomolecular and surgical therapies. Toll-like receptor (TLR) 2 and 4