Data-driven asthma endotypes defined from blood biomarker and gene expression data.

Autor: Barbara Jane George, David M Reif, Jane E Gallagher, ClarLynda R Williams-DeVane, Brooke L Heidenfelder, Edward E Hudgens, Wendell Jones, Lucas Neas, Elaine A Cohen Hubal, Stephen W Edwards

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117445 (2015)

The diagnosis and treatment of childhood asthma is complicated by its mechanistically distinct subtypes (endotypes) driven by genetic susceptibility and modulating environmental factors. Clinical biomarkers and blood gene expression were collected fr

Externí odkaz: https://doaj.org/article/00a83e8f18dd404ca0c1cbecf543077f

Comparison of mutagenic activities of several peroxyacyl nitrates

Autor: Tadeusz E. Kleindienst, Paul B. Shepson, David F. Smith, Edward E. Hudgens, Chris M. Nero, Larry T. Cupitt, Joseph J. Bufalini, Larry D. Claxton, F. R. Nestman

Publikováno v: Environmental and Molecular Mutagenesis. 16:70-80

Salmonella typhimurium, strain TA100 was exposed to a series of peroxyacyl nitrates including peroxyacetyl nitrate (PAN), peroxypropionyl nitrate (PPN), peroxybutyryl nitrate (PBN), peroxybenzoyl nitrate (PBzN), and chloroperoxyacetyl nitrate (CPAN).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba38480207b187165b7cb3f64b79cf0e
https://doi.org/10.1002/em.2850160204

Factors associated with self-reported health: implications for screening level community-based health and environmental studies

Autor: Jane E. Gallagher, Adrien A. Wilkie, Alissa Cordner, Edward E. Hudgens, Andrew J. Ghio, Rebecca J. Birch, Timothy J. Wade

Publikováno v: BMC Public Health, Vol 16, Iss 1, Pp 1-15 (2016)

Abstract Background Advocates for environmental justice, local, state, and national public health officials, exposure scientists, need broad-based health indices to identify vulnerable communities. Longitudinal studies show that perception of current

Externí odkaz: https://doaj.org/article/7f599f9c9b7e49a180be37baa9796630

Greener residential environment is associated with increased bacterial diversity in outdoor ambient air.

Autor: Styles JN; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA; Department of Pediatrics, Division of Allergy and Immunology, Chapel Hill, NC, USA. Electronic address: jnstyles@live.unc.edu., Egorov AI; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA., Griffin SM; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Cincinnati, OH, USA., Klein J; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA; North Carolina State University Libraries, Raleigh, NC, USA., Scott JW; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA., Sams EA; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA., Hudgens E; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA., Mugford C; United States Public Health Service Commissioned Corps, Research Triangle Park, NC, USA; The Agency for Toxic Substances and Disease Registry, Boston, MA, USA., Stewart JR; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Lu K; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jaspers I; Curriculum in Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Keely SP; United States Environmental Protection Agency, Center for Environmental Measurement and Monitoring, Office of Research and Development, Cincinnati, OH, USA., Brinkman NE; United States Environmental Protection Agency, Center for Environmental Solutions and Emergency Response, Office of Research and Development, Cincinnati, OH, USA., Arnold JW; Division of Gastroenterology and Hepatology, Department of Medicine, Microbiome Core Facility, Center for Gastrointestinal Biology and Disease, School of Medicine, University of North Carolina, Chapel Hill, NC, USA; Department of Molecular Genetics and Microbiology, Duke Microbiome Center, Duke University, Durham, NC, USA., Wade TJ; United States Environmental Protection Agency, Center for Public Health and Environmental Assessment, Office of Research and Development, Research Triangle Park, NC, USA.

Publikováno v: The Science of the total environment [Sci Total Environ] 2023 Jul 01; Vol. 880, pp. 163266. Date of Electronic Publication: 2023 Apr 05.

A Multiplex Noninvasive Salivary Antibody Assay for SARS-CoV-2 Infection and Its Application in a Population-Based Survey by Mail.

Autor: Egorov AI; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA., Griffin SM; U.S. Environmental Protection Agencygrid.418698.a, Cincinnati, Ohio, USA., Fuzawa M; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA., Kobylanski J; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA., Grindstaff R; U.S. Environmental Protection Agencygrid.418698.a, Research Triangle Park, North Carolina, USA., Padgett W; U.S. Environmental Protection Agencygrid.418698.a, Research Triangle Park, North Carolina, USA., Simmons S; U.S. Environmental Protection Agencygrid.418698.a, Research Triangle Park, North Carolina, USA., Hallinger DR; U.S. Environmental Protection Agencygrid.418698.a, Research Triangle Park, North Carolina, USA., Styles JN; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA.; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Wickersham L; U.S. Environmental Protection Agencygrid.418698.a, Research Triangle Park, North Carolina, USA., Sams E; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA., Hudgens E; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA., Wade TJ; U.S. Environmental Protection Agencygrid.418698.a, Chapel Hill, North Carolina, USA.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2021 Oct 31; Vol. 9 (2), pp. e0069321. Date of Electronic Publication: 2021 Sep 15.