Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edward Dziadulewicz"'
Autor:
Hanna Skrobanski, Kishan Vyas, Sally Bowditch, Lena Hubig, Edward Dziadulewicz, Louise Fish, Pooja Takhar, Siu Hing Lo
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background Tuberous sclerosis complex (TSC) is a rare genetic condition commonly accompanied by neurological and neuropsychological disorders, resulting in a high burden of illness for individuals and a substantial impact on their caregivers
Externí odkaz:
https://doaj.org/article/a7176b3eba8040fb863b7421cfd8da55
Autor:
Hanna Skrobanski, Kishan Vyas, Sally Bowditch, Lena Hubig, Edward Dziadulewicz, Louise Fish, Pooja Takhar, Siu Hing Lo
Publikováno v:
PharmacoEconomics - Open. 7:299-312
Publikováno v:
The British Journal of General Practice
BackgroundNausea and vomiting of pregnancy (NVP) is the most prevalent medical condition associated with pregnancy. The Royal College of Obstetricians and Gynaecologists published its first guidelines for management of NVP in 2016, although many curr
Autor:
Murat, Emre, Roberto, Bernabei, Rafael, Blesa, Roger, Bullock, Luis, Cunha, Hugo, Daniëls, Edward, Dziadulewicz, Hans, Förstl, Lutz, Frölich, Tomasz, Gabryelewicz, Oleg, Levin, James, Lindesay, Pablo, Martínez-Lage, Andreas, Monsch, Magda, Tsolaki, Teus, van Laar
Publikováno v:
CNS neurosciencetherapeutics. 16(4)
Cholinesterase inhibitors constitute one of the mainstays of treatment of Alzheimer disease (AD). Gastrointestinal side effects, difficulty accessing therapeutic doses and poor patient compliance have been identified as barriers to effective treatmen
Autor:
Melvyn Giles, Timothy Gallagher, William O. Moss, Edward Dziadulewicz, Michael B. Hursthouse, Mary E. Harman
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1793-1798
A series of γ,γ-dithioalkyl or dithioaryl ketene dithioacetals (3a), (3b), and (3c) has been prepared. Attempts to generate allylic anions under a variety of conditions from 1,1,3,3-tetrakis(phenylthio)propene (3a) and 1,1,3,3-tetrakis(methylthio)p
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :3367-3373
The synthesis of 1,1,3-tris(phenylthio)prop-1-ene (8) is described. Anion (9), obtained by deprotonation of (8) with lithium di-isopropylamide, reacts with a wide range of electrophiles to give the γ-substituted adducts (10) exclusively. The relativ
Autor:
Edward Dziadulewicz, Timothy Gallagher
Publikováno v:
Tetrahedron Letters. 26:4547-4550
Lithiation of 1,1-bis(phenylthio)-3-phenylthio-1-propene 3 and reaction with a range of electrophiles gave exclusively the γ-substituted product 4 . This reagent has been used in a short synthesis of the pheromone, (±)-eldanolide.
Publikováno v:
Liebigs Annalen der Chemie. 1989:1215-1232
The enantiomerically pure glycine derivatives (R)- and (S)-Boc-BMI, commercially available on a kg scale, are used as starting materials (Scheme 1) for the preparation of (i) open-chain amino acids such as α-deuterio amino acids (4, 5), β-arylalani