Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Edward Dudek"'
Autor:
Andrea Caceres, Fu Shang, Eric Wawrousek, Qing Liu, Orna Avidan, Ales Cvekl, Ying Yang, Aydin Haririnia, Andrew Storaska, David Fushman, Jer Kuszak, Edward Dudek, Donald Smith, Allen Taylor
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13331 (2010)
The eye lens presents a unique opportunity to explore roles for specific molecules in cell proliferation, differentiation and development because cells remain in place throughout life and, like red blood cells and keratinocytes, they go through the m
Externí odkaz:
https://doaj.org/article/9bdcfd04c17c462293502d2a19a67fa3
Autor:
Li-Rong Shao, F. Edward Dudek
Publikováno v:
Journal of neurophysiology. 128(6)
Burst discharges in the developing brain can provide valuable insights into epileptogenesis. We show that the immature hippocampal CA1 area is capable of generating all-or-none (i.e., network) bursts, which transitions to graded (i.e., nonnetwork) bu
Autor:
Jay Spampanato, Kyle Berger, Cecelia E. Jackson, John H. McDonough, Hilary S. McCarren, F. Edward Dudek, Bryan S. Barker, David T. Yeung
Publikováno v:
Neuroscience. 463:143-158
Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant tre
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:59-68
Organophosphate (OP) exposure induces status epilepticus (SE), a medical emergency with high morbidity and mortality. Current standard medical countermeasures lose efficacy with time so that treatment delays, in the range of tens of minutes, result i
Autor:
David T. Yeung, Jay Spampanato, Bryan S. Barker, Cecelia Jackson, F. Edward Dudek, John H. McDonough, Hilary S. McCarren, Melissa Smolik, Eden N. Hornung
Publikováno v:
Neuroscience
Organophosphorus (OP) compounds are deadly chemicals that exert their intoxicating effects through the irreversible inhibition of acetylcholinesterase (AChE). In addition to an excess of peripheral ailments, OP intoxication induces status epilepticus
Autor:
Jon D. Reuter, Daniel S. Barth, Rebecca A. Kubiak, Toni T. Mufford, Carmen J. Booth, F. Edward Dudek, Jeremy J. Taylor
Publikováno v:
The Journal of Neuroscience. 39:4829-4841
Absence epilepsy is a heritable human neurological disorder characterized by brief nonconvulsive seizures with behavioral arrest, moderate-to-severe loss of consciousness (absence), and distinct spike-wave discharges (SWDs) in the EEG and electrocort
Publikováno v:
Epilepsia. 60:636-647
OBJECTIVE Animal models of chronic epilepsy with spontaneous recurrent seizures (SRSs) may be useful in the discovery and mechanistic analyses of antiseizure drugs (ASDs). Carbamazepine (CBZ), a widely used ASD with a well-defined mechanism, was anal
Publikováno v:
In Neuropharmacology 2009 56(2):414-421
Autor:
F. Edward Dudek, Sean Tatum, Zachariah Z. Smith, Jeremy J. Taylor, David Poulsen, Daniel S. Barth
Publikováno v:
Journal of neurophysiology. 125(6)
Unilateral-onset spike-wave discharges (SWDs) following fluid percussion injury (FPI) in rats have been used for nearly two decades as a model for complex partial seizures in human posttraumatic epilepsy (PTE). This study determined if SWDs with a un
Autor:
Bryan S, Barker, Jay, Spampanato, Hilary S, McCarren, Kyle, Berger, Cecelia E, Jackson, David T, Yeung, F Edward, Dudek, John H, McDonough
Publikováno v:
Neuroscience
Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant tre