Zobrazeno 1 - 10
of 608
pro vyhledávání: '"Edward Dudek"'
Autor:
Li-Rong Shao, F. Edward Dudek
Publikováno v:
Journal of neurophysiology. 128(6)
Burst discharges in the developing brain can provide valuable insights into epileptogenesis. We show that the immature hippocampal CA1 area is capable of generating all-or-none (i.e., network) bursts, which transitions to graded (i.e., nonnetwork) bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ca9147423518b0af1954e3675ff527
https://pubmed.ncbi.nlm.nih.gov/36382903
https://pubmed.ncbi.nlm.nih.gov/36382903
Autor:
Timothy B. C. Johnstone, Hilary S. McCarren, Jay Spampanato, F. Edward Dudek, John H. McDonough, Derk Hogenkamp, Kelvin W. Gee
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABAARs) that rapidly internalize during status epilepticus (SE). Extr
Externí odkaz:
https://doaj.org/article/25d1ae99c446488ba9de5d89a56a1187
Autor:
Jay Spampanato, Kyle Berger, Cecelia E. Jackson, John H. McDonough, Hilary S. McCarren, F. Edward Dudek, Bryan S. Barker, David T. Yeung
Publikováno v:
Neuroscience. 463:143-158
Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e9bf76b1e29464d43dcbd1c8607ea5
https://doi.org/10.1016/j.neuroscience.2021.03.029
https://doi.org/10.1016/j.neuroscience.2021.03.029
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:59-68
Organophosphate (OP) exposure induces status epilepticus (SE), a medical emergency with high morbidity and mortality. Current standard medical countermeasures lose efficacy with time so that treatment delays, in the range of tens of minutes, result i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2915ba9f7513de36872c1e26b8bf9
https://doi.org/10.1124/jpet.120.000175
https://doi.org/10.1124/jpet.120.000175
Autor:
David T. Yeung, Jay Spampanato, Bryan S. Barker, Cecelia Jackson, F. Edward Dudek, John H. McDonough, Hilary S. McCarren, Melissa Smolik, Eden N. Hornung
Publikováno v:
Neuroscience
Organophosphorus (OP) compounds are deadly chemicals that exert their intoxicating effects through the irreversible inhibition of acetylcholinesterase (AChE). In addition to an excess of peripheral ailments, OP intoxication induces status epilepticus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a183ea9a758cd65879acd4ba3a50be5
https://doi.org/10.1016/j.neuroscience.2019.11.020
https://doi.org/10.1016/j.neuroscience.2019.11.020
Autor:
Jon D. Reuter, Daniel S. Barth, Rebecca A. Kubiak, Toni T. Mufford, Carmen J. Booth, F. Edward Dudek, Jeremy J. Taylor
Publikováno v:
The Journal of Neuroscience. 39:4829-4841
Absence epilepsy is a heritable human neurological disorder characterized by brief nonconvulsive seizures with behavioral arrest, moderate-to-severe loss of consciousness (absence), and distinct spike-wave discharges (SWDs) in the EEG and electrocort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb1de4ec7e935f7fc212b44c61196d6
https://doi.org/10.1523/jneurosci.1167-18.2019
https://doi.org/10.1523/jneurosci.1167-18.2019
Publikováno v:
Epilepsia. 60:636-647
OBJECTIVE Animal models of chronic epilepsy with spontaneous recurrent seizures (SRSs) may be useful in the discovery and mechanistic analyses of antiseizure drugs (ASDs). Carbamazepine (CBZ), a widely used ASD with a well-defined mechanism, was anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04480f7af4d1d2a59492e2aad20c0618
https://doi.org/10.1111/epi.14680
https://doi.org/10.1111/epi.14680
Publikováno v:
In Neuropharmacology 2009 56(2):414-421
Autor:
F. Edward Dudek, Sean Tatum, Zachariah Z. Smith, Jeremy J. Taylor, David Poulsen, Daniel S. Barth
Publikováno v:
Journal of neurophysiology. 125(6)
Unilateral-onset spike-wave discharges (SWDs) following fluid percussion injury (FPI) in rats have been used for nearly two decades as a model for complex partial seizures in human posttraumatic epilepsy (PTE). This study determined if SWDs with a un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4102d87d663bd9eb8f5c6121fff38843
https://pubmed.ncbi.nlm.nih.gov/33949882
https://pubmed.ncbi.nlm.nih.gov/33949882
Autor:
Bryan S, Barker, Jay, Spampanato, Hilary S, McCarren, Kyle, Berger, Cecelia E, Jackson, David T, Yeung, F Edward, Dudek, John H, McDonough
Publikováno v:
Neuroscience
Benzodiazepines are the primary treatment option for organophosphate (OP)-induced status epilepticus (SE), but these antiseizure drugs (ASDs) lose efficacy as treatment is delayed. In the event of a mass civilian or military exposure, significant tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::392ec4cba73e3e000586b148bdaa97c5
https://pubmed.ncbi.nlm.nih.gov/33836243
https://pubmed.ncbi.nlm.nih.gov/33836243