Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Edward Doherty"'
Autor:
David J. Mooney, Glenn Dranoff, Edward Doherty, Des White, Sarah A. Lewin, R. Warren Sands, Chris Johnson, Catia Verbeke, Omar A. Ali
PDF file - 129KB, Activated dendritic cell numbers at the vaccine implant site (S1); The kinetics of activated dendritic cell generation at vaccine site (S2); IFN-a production at vaccine sites (S3); TNF-a production at vaccine sites (S4); Prophylacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab44d605463474e33593f63b71f694f
https://doi.org/10.1158/0008-5472.22400741.v1
https://doi.org/10.1158/0008-5472.22400741.v1
Autor:
David J. Mooney, Glenn Dranoff, Edward Doherty, Des White, Sarah A. Lewin, R. Warren Sands, Chris Johnson, Catia Verbeke, Omar A. Ali
PDF file - 237KB, Vaccine induction of inflammatory cytokine production at the vaccine site (S1); The correlation between local cytokine concentration and survival outcome in vaccinated mice (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c6abce299acfba132f1467548fee26
https://doi.org/10.1158/0008-5472.22400738
https://doi.org/10.1158/0008-5472.22400738
Autor:
David J. Mooney, Glenn Dranoff, Edward Doherty, Des White, Sarah A. Lewin, R. Warren Sands, Chris Johnson, Catia Verbeke, Omar A. Ali
The innate cellular and molecular components required to mediate effective vaccination against weak tumor-associated antigens remain unclear. In this study, we used polymeric cancer vaccines incorporating different classes of adjuvants to induce tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2597ca6a6548b83d219841f247ffba5f
https://doi.org/10.1158/0008-5472.c.6505655
https://doi.org/10.1158/0008-5472.c.6505655
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION. Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with upstream regulatory roles in innate and adaptive immunity and is implicated in the pathogenesis of autoimmune diseases including rheumatoid arthrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2c879edce9b6c7c69cb3e11887afc4
https://europepmc.org/articles/PMC6800059/
https://europepmc.org/articles/PMC6800059/
Autor:
Paul Edward Doherty
Publikováno v:
Journal of Marine Engineering & Technology. 15:97-106
This paper advocates the use of shipboard procedures as a strategy for bridging the knowledge gap. It also recognises that an over-reliance reflects a failure to equip seafarers with the appropriate prior knowledge. Maritime accident reports frequent
Autor:
Paul Edward Doherty
Publikováno v:
WMU Journal of Maritime Affairs. 15:97-125
The notion of operating and maintenance manuals being validated as fit for purpose is based largely on conjecture, as causal factors contributing to rule-based (procedure-based) human error at sea are under-theorised and under-researched. Human facto
Autor:
Edward Doherty, Andras Perl
Publikováno v:
Reactive Oxygen Species.
Properly assessing mitochondrial health is crucial to understand their role in disease. MitoTracker green (MTG) and nonylacridine orange (NAO) are fluorescent probes which have been commonly used to assess mitochondrial mass. This is based on the ass
Publikováno v:
Antioxidants & Redox Signaling. 21:56-65
Aims: Systemic lupus erythematosus (SLE) patients' peripheral blood lymphocytes (PBL) show mitochondrial dysfunction and oxidative stress. To determine the electrochemical bases of mitochondrial dysfunction, we measured electron transport chain (ETC)
Autor:
Adam Bartos, Eduardo Bonilla, Brandon Clair, Jianghong Yu, Andras Perl, Paul E. Phillips, Hajra Tily, Edward Doherty, Tiffany Caza, Ricardo Garcia, Stephen V. Faraone, Irene Ramos, Ioana L. Coman, Zhi-Wei Lai, John R. Jimah, Robert Hanczko, Lisa Francis, Maha Dawood, Gabriella Miklossy
Publikováno v:
Arthritis & Rheumatism. 64:2937-2946
Objective Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can be regulated through mitochondrial transmembrane potential (Δψm) and mammalian target of rapamycin (mTOR) by glutathione (GSH). This randomized, double-blin
Autor:
David Fernandez, György Nagy, Tiffany Telarico, Agnes Koncz, Paul E. Phillips, Péter Gergely, Eduardo Bonilla, Edward Doherty, Andras Perl
Publikováno v:
Autoimmunity. 41:287-297
Genetic and environmental factors are believed to influence development of systemic lupus erythematosus (SLE). Endogenous retroviruses (ERV) correspond to the integrated proviral form of infectious retroviruses, which are trapped within the genome du