Výsledky vyhledávání - "Edward De Maeyer"

Effect of MAO A knockout on catecholamines in mouse brain regions: dopamine and norepinephrine in the cortex are unaffected by MAO A deficiency

Autor: Nina K. Popova, Ekaterina A. Morosova, Michael A. Gilinsky, Tamara G. Amstislavskaya, Isabelle Seif, Edward De Maeyer

Publikováno v: Biogenic Amines. 19:189-196

The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the levels of norepinephrine (NE), dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) in the midbrain, hypothalamus, hippocampus, striatum, amygdala

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfa455d17db1960353a03f2d293ae5d6
https://doi.org/10.1163/156939105774288753

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Abnormal Phrenic Motoneuron Activity and Morphology in Neonatal Monoamine Oxidase A-Deficient Transgenic Mice: Possible Role of a Serotonin Excess

Autor: Céline Bou-Flores, Jeanne Lanoir, R. Monteau, Anne-Marie Lajard, Isabelle Seif, Edward De Maeyer, Gérard Hilaire

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2000, 20 (12), pp.4646-56
Journal of Neuroscience, Society for Neuroscience, 2000, 20 (12), pp.4646-56

In rodent neonates, the neurotransmitter serotonin (5-HT) modulates the activity of both the medullary respiratory rhythm generator and the cervical phrenic motoneurons. To determine whether 5-HT also contributes to the maturation of the respiratory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13d00d442ff94583023da3b11645d28
https://doi.org/10.1523/jneurosci.20-12-04646.2000

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Retrovirally Mediated IFN-β Transduction of Macrophages Induces Resistance to HIV, Correlated with Up-Regulation of RANTES Production and Down-Regulation of C-C Chemokine Receptor-5 Expression

Autor: Isabelle Cremer, V. Vieillard, Edward De Maeyer

Publikováno v: The Journal of Immunology. 164:1582-1587

Constitutive expression of IFN-β by HIV target cells may be an alternative or complementary therapeutic approach for the treatment of AIDS. We show that macrophages derived from CD34+ cells from umbilical cord blood can be efficiently transduced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8bb85096474a26cdfd588d418f4788
https://doi.org/10.4049/jimmunol.164.3.1582

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Transfer of Human CD4 + T Lymphocytes Producing Beta Interferon in Hu-PBL-SCID Mice Controls Human Immunodeficiency Virus Infection

Autor: Vincent Vieillard, Stephane Jouveshomme, Patrice Debré, Eric Jean-Pierre, Edward De Maeyer, Nicole Leflour, Brigitte Autran

Publikováno v: Journal of Virology. 73:10281-10288

Beta interferon (IFN-β) exerts pleiotropic antiretroviral activities and affects many different stages of the human immunodeficiency virus (HIV) infectious cycle in IFN-treated cells. To explore whether transfer of genetically engineered human CD4 +

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0f2087797133b9412d68dfe5db6fe6
https://doi.org/10.1128/jvi.73.12.10281-10288.1999

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Ketanserin and tetrabenazine abolish aggression in mice lacking monoamine oxidase A

Autor: Jean C. Shih, Michael James Ridd, Woerner P. Meehan, Kevin Chen, Isabelle Seif, Edward De Maeyer, Mei-Ping Kung

Publikováno v: Brain Research. 835:104-112

Mice deficient in monoamine oxidase A (MAO A) have elevated brain levels of 5-HT and manifest enhanced aggression. We used these mice as a model to study the role of 5-HT in aggression. Our results show that ketanserin and tetrabenazine (TBZ) strikin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b565cd9887b5d4b84f179a46cdf0271
https://doi.org/10.1016/s0006-8993(99)01478-x

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Macaque Lymphocytes Transduced by a Constitutively Expressed Interferon beta Gene Display an Enhanced Resistance to SIVmac251 Infection

Autor: Edward De Maeyer, Véronique Rousseau, Dominique Dormont, Roger Le Grand, Evelyne Lauret, F Matheux

Publikováno v: Human Gene Therapy. 10:429-440

We are developing a method of gene therapy of HIV infection based on the low constitutive expression of an interferon beta (IFN-beta) gene in HIV target cells. Herein we report the first step in the development of a relevant animal model, provided by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8d588a623367ebfe17fedccb68cee9
https://doi.org/10.1089/10430349950018878

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Electron-microscopic study of MAOB-containing structures in the nucleus accumbens shell: using MAOA-deficient transgenic mice

Autor: Jean-Louis Valatx, Keiko Ikemoto, Toshihiro Maeda, Kunio Kitahama, Yoshimitsu Tokunaga, Isabelle Seif, Edward De Maeyer

Publikováno v: Brain Research. 771:163-166

MAOB-containing structures in the nucleus accumbens were ultrastructurally studied for the first time, using MAOA-deficient transgenic mice and MAO enzyme histochemistry. Among the striatal structures, the nucleus accumbens, and in particular its dor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315290b54c460f7cb615a8857803a64c
https://doi.org/10.1016/s0006-8993(97)00909-8

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Monoamine oxidase B (MAOB)-containing structures in MAOA-deficient transgenic mice

Autor: Toshihiro Maeda, Keiko Ikemoto, Jean-Louis Valatx, Isabelle Seif, Edward De Maeyer, Kunio Kitahama

Publikováno v: Brain Research. 771:121-132

Monoamine oxidase (MAO)-containing structures were studied for the first time in type A MAO (MAOA)-deficient transgenic mice (Tg8) derived from C3H strain, using MAO enzyme histochemistry. In this mutant line, MAOA activity was not detected in neuron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac375aceb50e2a2744e77657c02802a
https://doi.org/10.1016/s0006-8993(97)00832-9

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Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice

Autor: Stephen Maren, Isabelle Seif, Edward De Maeyer, Richard F. Thompson, Lu Chen, Jean C. Shih, Jeansok J. Kim, Shaowen Bao, Kevin Chen, Stephan G. Anagnostaras, Michael S. Fanselow

Publikováno v: Proceedings of the National Academy of Sciences. 94:5929-5933

Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex, hippocampus, and cerebellum, compared with normal wild-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058706597924474cbe8c03b8255d77e5
https://doi.org/10.1073/pnas.94.11.5929

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Lack of Barrels in the Somatosensory Cortex of Monoamine Oxidase A–Deficient Mice: Role of a Serotonin Excess during the Critical Period

Autor: Patricia Gaspar, Isabelle Seif, Edward De Maeyer, Tania Vitalis, Olivier Cases, Constantino Sotelo

Publikováno v: Neuron. 16:297-307

In a transgenic mouse line (Tg8) deficient for the gene encoding monoamine oxidase A (MAOA), we show that the primary somatosensory cortex (S1) lacks the characteristic barrel-like clustering of layer IV neurons, whereas normal pattern formation exis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04333fb8a5d680c6c7ed0e87b79b8ae
https://doi.org/10.1016/s0896-6273(00)80048-3

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