Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Edward D. Savory"'
Autor:
Stephen G. Davies, Kenneth B. Ling, Angela J. Russell, Humberto Rodriguez‐Solla, Edward D. Savory, Yutaka Ishii, Caroline Aciro, Andrew Smith, Min-Suk Key, Catherine O'Leary-Steele, Paul M. Roberts, A. Christopher Garner, Hitesh J. Sanganee, James E. Thomson, R. Shyam Prasad
Homochiral (E)- and (Z)-enamides derived from SuperQuat (S)-4-phenyl-5,5-dimethyl-oxazolidin-2-one undergo highly diastereoselective epoxidation upon treatment with dimethyldioxirane. Subsequent epoxide opening with meta-chlorobenzoic acid proceeds v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a959900a453cd24162d6992b61b38e5
https://doi.org/10.1016/j.tet.2008.07.012
https://doi.org/10.1016/j.tet.2008.07.012
Autor:
Ian A. Hunter, Rebecca L. Nicholson, Stephen G. Davies, Paul M. Roberts, Edward D. Savory, Andrew D. Smith
Publikováno v:
Tetrahedron. 60:7553-7577
α-Dibenzylamino- and α-benzyloxy- derivatives of N-acetyl-(S)-4-benzyl-5,5-dimethyloxazolidin-2-one readily undergo highly stereoselective boron mediated syn-aldol reactions with a range of aromatic and aliphatic aldehydes, generating the syn-aldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9d1f27ffb2868ecbec82b89d7d52e3
https://doi.org/10.1016/j.tet.2004.05.123
https://doi.org/10.1016/j.tet.2004.05.123
Autor:
David J. Watkin, Stephen G. Davies, Edward D. Savory, Andrew D. Smith, Steven D. Bull, Richard Vickers, Elena Buñuel, A. Christopher Garner
Publikováno v:
Org. Biomol. Chem.. 1:2531-2542
Diketopiperazinespirocyclopropane 12 is prepared in > 98% d.e. via the conjugate addition of a phosphorus ylide to (6S)-N,N'-bis(p-methoxybenzyl)-3-methylenepiperazine-2,5-dione 2. Deprotection and hydrolysis of adduct 12 and subsequent peptide coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faec768f4c1bfb2f8896e0be78876c2c
https://doi.org/10.1039/b303348a
https://doi.org/10.1039/b303348a
Publikováno v:
Tetrahedron. 58:9387-9401
The propensity for N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O carbonyl transfer makes these L-serine derived chiral auxiliaries unsuitable for attachment to polymers. © 2002 Elsevier Science Ltd. All rights reserved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb18324fe78ba246a12e7aecb636f9b
https://doi.org/10.1016/s0040-4020(02)01223-1
https://doi.org/10.1016/s0040-4020(02)01223-1
Autor:
Christopher J. Goodwin, Edward D. Savory, Paul M. Roberts, Andrew Smith, Ai M. Flechter, David Hepworth, Stephen G. Davies, Alexander N. Chernega, R. Shyam Prasad, James E. Thomson
Publikováno v:
ChemInform. 41
Alternatively, the chiral auxiliary promotes aldol reactions to give syn-aldol products such as (XIII), (XVI), or (XX) with good diastereocontrol over both newly generated stereogenic centers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10565ddb9b2a97014bf9e42f6a1cdbb9
https://doi.org/10.1002/chin.201039053
https://doi.org/10.1002/chin.201039053
Autor:
Dirk L. Elend, James E. Thomson, Edward D. Savory, Simon Jones, Paul M. Roberts, Andrew D. Smith, Stephen G. Davies
Publikováno v:
ChemInform. 41
The synthesis of α-vinyl-β-hydroxyesters and α-ethylidene-β-hydroxyesters (β-substituted Baylis–Hillman products) via the dienolate aldol reaction of (E)-N-crotonoyl C(4)-isopropyl SuperQuat is described. High levels of syn-diastereoselectivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f16237ef3fbbb68b096db6c646e682
https://doi.org/10.1002/chin.201002058
https://doi.org/10.1002/chin.201002058
Autor:
Stephen G. Davies, Edward D. Savory, James E. Thomson, Andrew D. Smith, Paul M. Roberts, Simon Jones, Dirk L. Elend
Publikováno v:
TETRAHEDRON. 65(37)
The synthesis of α-vinyl-β-hydroxyesters and α-ethylidene-β-hydroxyesters (β-substituted Baylis-Hillman products) via the dienolate aldol reaction of (E)-N-crotonoyl C(4)-isopropyl SuperQuat is described. High levels of syn-diastereoselectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf21fcfbb8e862044f23daf83e3b4f2
http://ora.ox.ac.uk/objects/uuid:16c2ea81-89f7-40ad-b744-c81a44956509
http://ora.ox.ac.uk/objects/uuid:16c2ea81-89f7-40ad-b744-c81a44956509
Autor:
Rebecca L. Nicholson, Paul M. Roberts, A. Christopher Garner, Stephen G. Davies, James E. Thomson, Andrew D. Smith, Edward D. Savory, James M. Osborne
Publikováno v:
Organicbiomolecular chemistry. 7(12)
The doubly diastereoselective [3,3]-sigmatropic aza-Claisen rearrangement of silylketene aminals derived from 5-substituted (3S,4E,alphaR)-1-benzyloxy-3-[N-acyl-N-(alpha-methylbenzyl)amino]pent-4-enes furnishes 2,3-disubstituted (R)-N-alpha-methylben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3c909ca4938bf4e7175cbbffbbc0bb
https://pubmed.ncbi.nlm.nih.gov/19503936
https://pubmed.ncbi.nlm.nih.gov/19503936
Autor:
Rebecca L. Nicholson, Andrew D. Smith, Paul M. Roberts, Stephen G. Davies, Angela J. Russell, Paul D. Price, James E. Thomson, Edward D. Savory
Publikováno v:
TETRAHEDRON-ASYMMETRY. 20(6-8)
Treatment of a range of homochiral unsaturated β-amino esters (containing a cis-dioxolane unit) with iodine promotes a novel ring-closing alkene iodoamination reaction which proceeds with concomitant N-debenzylation, providing a simple and stereosel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca062f63e6a8caaf7347f661847cdc73
http://ora.ox.ac.uk/objects/uuid:97ea132b-1769-4e6a-b746-ededc5d33054
http://ora.ox.ac.uk/objects/uuid:97ea132b-1769-4e6a-b746-ededc5d33054
Autor:
Edward D. Savory, Angela J. Russell, Timothy D. W. Claridge, Andrew D. Smith, Stephen G. Davies, Paul M. Roberts, Mario E. C. Polywka
Publikováno v:
Organic letters. 10(23)
Integration of a (13)C-(1)H satellite peak of a given (12)C-(1)H parent resonance within a quantitative (1)H NMR spectrum and comparison to the minor component represents a simple protocol for the accurate determination of diastereoisomeric ratios of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb237f0e0c6ab98f4c4ccaf6d4c8b09
http://ora.ox.ac.uk/objects/uuid:d0955bd7-2132-48c6-83e8-e4d59a31f8e7
http://ora.ox.ac.uk/objects/uuid:d0955bd7-2132-48c6-83e8-e4d59a31f8e7