Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Edward D. French"'
Autor:
Eric M. Janezic, Edward D. French, Marco Contreras, Swetha Uppalapati, Jean Marc Fellous, Stephanie Nagl
Publikováno v:
Behavioural Pharmacology. 27:704-717
Post-traumatic stress disorder (PTSD) is in part due to a deficit in memory consolidation and extinction. Oxytocin (OXT) has anxiolytic effects and promotes prosocial behaviors in both rodents and humans, and evidence suggests that it plays a role in
Autor:
Edward D. French, Kimberly E. Edelman-Vogelsang, Jean Marc Fellous, Nadia S. Corral-Frías, Ryan P. Lahood
Publikováno v:
Neuropsychopharmacology. 38:350-363
Post-traumatic stress disorder (PTSD) is an anxiety disorder of considerable prevalence in individuals who have experienced a traumatic event. Studies of the neural substrate of this disorder have focused on the role of areas such as the hippocampus,
Publikováno v:
Neuropsychopharmacology. 33:2747-2759
The CB(1) cannabinoid receptor is implicated in the rewarding properties of many drugs of abuse, including cocaine. While CB(1) receptor involvement in the acute rewarding properties of cocaine is controversial, CB(1) antagonists such as SR141716 (ri
Publikováno v:
Neuropsychopharmacology. 32:1558-1569
Recreational abuse of toluene-containing volatile inhalants by adolescents is a significant public health problem. The mechanisms underlying the abuse potential of such substances remain unclear, but could involve increased activity in mesoaccumbal d
Autor:
Edward D. French, Arthur C. Riegel
Publikováno v:
Annals of the New York Academy of Sciences. 965:281-291
Inhalant abuse remains a significant health problem among the younger segment of society. In fact, the use of inhalants in this population trails only that of nicotine, alcohol, and marijuana. Toluene is a common ingredient in many of the substances
Autor:
Arthur C. Riegel, Edward D. French
Publikováno v:
Pharmacology & Toxicology. 85:37-43
Inhalant abuse is a common, potentially lethal, form of drug abuse. Although the putative psychotropic compo- nent of some popularly abused inhalants appears often to be the organic solvent toluene, its effects on midbrain neurones which comprise rew
Publikováno v:
Psychopharmacology. 128:83-88
The effects of the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801, on cocaine self-administration were investigated. Forty-six male Wistar rats were trained to intravenously self-administer four unit doses of cocaine (0.19, 0.
Publikováno v:
Life Sciences. 59:PL199-PL205
Ibogaine, an indole containing alkaloid, has been shown to reduce the rate of injection of morphine and cocaine in self-administration protocols. Since morphine- and cocaine-induced modulation of dopamine release is impulse dependent and essential fo
Autor:
Edward D. French
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:441-443
Pharmacologists belong to a special fraternity, one whose members love to study drugs, even though we may have highly individualized viewpoints about what aspect of drug action delights our intellectual curiosities. Still it is this passion to unders
Autor:
James A. Bourland, Edward D. French
Publikováno v:
Drug and Alcohol Dependence. 40:111-114
Remoxipride, a selective D2-dopamine receptor antagonist with preferential activity for mesolimbic-mediated behaviors, was assessed for its potential to block cocaine self-administration. The effects of remoxipride (RMX) were evaluated using fixed-ra