Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Edward Chung Yern Wang"'
Autor:
Edward Chung Yern Wang, Luis Nobre, Martin Potts, Alice Fletcher-Etherington, Katie Nightingale, Zerbe C, Nicolás M. Suárez, Jenna Nichols, Robin Antrobus, Andrew J. Davison, Jack W. Houghton, Leah M. Hunter, Michael P. Weekes, Richard J. Stanton, Ceri Alan Fielding, Blair L. Strang
Human cytomegalovirus (HCMV) is an important human pathogen and a paradigm of viral immune evasion, targeting intrinsic, innate and adaptive immunity. We have employed two novel, orthogonal multiplexed tandem mass tag-based proteomic screens to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb899ad069b60b78c6c6a6ccf4270619
https://www.repository.cam.ac.uk/handle/1810/331636
https://www.repository.cam.ac.uk/handle/1810/331636
Autor:
Jane Turton, Fraser L. Collins, Laura R. McCabe, Edward Chung Yern Wang, Anwen Sian Williams, Michael D. Stone
Publikováno v:
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-9 (2019)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background\ud \ud Oestrogen-deficiency induced by menopause is associated with reduced bone density and primary osteoporosis, resulting in an increased risk of fracture. While the exact etiology of menopause-induced primary osteoporotic bone loss is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf01819eb0bb64c006fa4eda65c4386d
http://link.springer.com/article/10.1186/s12891-019-2704-z
http://link.springer.com/article/10.1186/s12891-019-2704-z
Autor:
Fabio T. M. Costa, Paul J. Lehner, Sam J. Wilson, Suzannah J. Rihn, David Robertson, Srikeerthana Kuchi, Quan Gu, Thomas W M Crozier, Alfredo Castello-Palomares, Rute Maria Pinto, Elena Sugrue, Matthew L. Turnbull, Isaric C-Investigators, Colin Loney, Monique Freire Santana, Jay Allan, Luiz Carlos de Lima Ferreira, Spyros Lytras, Antonia Ho, Natalia Cameron-Ruiz, Richard J. Stanton, Ruth F. Jarrett, Vanessa Herder, Arthur Wickenhagen, Innes Jarmson, Bo Wang, Sara Clohisey, Edward Chung Yern Wang, Matthias Marti, Massimo Palmarini, Kenneth Baillie, Marko Noerenberg, Joao Luiz Da Silva Filho, Douglas G. Stewart, Margus Varjak, Edward J. D. Greenwood, Simon Swingler
Cell autonomous antiviral defenses can inhibit the replication of viruses and reduce transmission and disease severity. To better understand the antiviral response to SARS-CoV-2, we used interferon-stimulated gene (ISG) expression screening to reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd517e51ccb503d025f6bea1c5a2cbb
https://doi.org/10.1101/2021.05.05.21256681
https://doi.org/10.1101/2021.05.05.21256681
Autor:
Richard J. Stanton, Nicolás M. Suárez, David Price, Rebecca J. Aicheler, Kristin Ladell, Gavin William Grahame Wilkinson, Virginia-Maria Vlahava, Mark R. Wills, Edward Chung Yern Wang, Andrew J. Davison, Lihui Zhuang, Michael P. Weekes, Isa Murrell, Kelly L. Miners, Eleanor Y. Lim
Publikováno v:
The Journal of Clinical Investigation
Human cytomegalovirus (HCMV) is a ubiquitous pathogen that causes severe disease following congenital infection and in immunocompromised individuals. No vaccines are licensed, and there are limited treatment options. We now show that the addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220474fa1e0c6b82423f686272c346da
http://europepmc.org/articles/PMC7880312
http://europepmc.org/articles/PMC7880312
Autor:
Becca Asquith, Rhiannon E. Jones, Kristin Ladell, Yan Zhang, Julio Lahoz-Beneytez, Laureline Roger, Raya Ahmed, Derek C. Macallan, Edward Chung Yern Wang, Duncan M. Baird, Kelly L. Miners, Joseph M. McCune, Christina Baboonian, Marc K. Hellerstein, David Price
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2020, 33 (11), pp.108501. ⟨10.1016/j.celrep.2020.108501⟩
Cell Reports, Vol 33, Iss 11, Pp 108501-(2020)
e5
e1
Cell Reports, Elsevier Inc, 2020, 33 (11), pp.108501. ⟨10.1016/j.celrep.2020.108501⟩
Cell Reports, Vol 33, Iss 11, Pp 108501-(2020)
e5
e1
Summary A central paradigm in the field of lymphocyte biology asserts that replicatively senescent memory T cells express the carbohydrate epitope CD57. These cells nonetheless accumulate with age and expand numerically in response to persistent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019bd1176b8dcb79c13d493b4d25cfba
https://hal.archives-ouvertes.fr/hal-03204476
https://hal.archives-ouvertes.fr/hal-03204476
Autor:
Joachim Jakob Bugert, Ceri Alan Fielding, James A. Traherne, Hana Elasifer, James A. Davies, Gavin William Grahame Wilkinson, Richard J. Stanton, Edward Chung Yern Wang, Nicole Gruber, Rebecca Aicheler, Virginie Prod'homme, Dawn L. Roberts, Simone K. Forbes, Mihil Patel
Molluscum contagiosum virus (MCV) is a common cause of benign skin lesions in young children and currently the only endemic human poxvirus. Following the infection of primary keratinocytes in the epidermis, MCV induces the proliferation of infected c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21758b5339af4f65ac793bf53eb7a216
Autor:
Gavin William Grahame Wilkinson, Jenna Nichols, Edward L. Huttlin, Luis Nobre, Katie Nightingale, James A. Davies, Benjamin J. Ravenhill, Edward Chung Yern Wang, Andrew J. Davison, Lior Soday, Robin Antrobus, Sepehr Seirafian, Richard J. Stanton, Michael P. Weekes
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Human cytomegalovirus (HCMV) extensively modulates host cells, downregulating >900 human proteins during viral replication and degrading ≥133 proteins shortly after infection. The mechanism of degradation of most host proteins remains unresolved, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd80d8b82509dc95ceb2f9514134958
https://www.repository.cam.ac.uk/handle/1810/301478
https://www.repository.cam.ac.uk/handle/1810/301478
Autor:
Edward Chung Yern Wang, Richard J. Stanton, Ceri Alan Fielding, Peter Tomasec, Robin Antrobus, Colin Davies, Gavin William Grahame Wilkinson, Michael P. Weekes, Andrew J. Davison, Katie Nightingale
Publikováno v:
Access Microbiology. 1
Human Cytomegalovirus (HCMV) is a master immune regulator, encoding multiple proteins that modulate a variety of immune signalling pathways. We previously performed a systematic proteomic analysis of temporal changes in host and viral proteins throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae7e27c1377745ccba3c0f692295b99b
https://doi.org/10.1099/acmi.ac2019.po0431
https://doi.org/10.1099/acmi.ac2019.po0431
Autor:
Christopher John Von Ruhland, Michael P. Weekes, Lauren Kerr, Lior Soday, Richard J. Stanton, Edward Chung Yern Wang
Publikováno v:
Access Microbiology. 1
Human cytomegalovirus (HCMV) rapidly mutates during in vitro passage, and this strongly alters the way the virus spreads. In vivo HCMV spreads by direct cell-cell contact, as do recent clinical isolates. In contrast, passaged strains spread via cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d41fd3588616baec52cfd40a26d64d5
https://doi.org/10.1099/acmi.ac2019.po0329
https://doi.org/10.1099/acmi.ac2019.po0329
Publikováno v:
Arthritis & Rheumatology. 68:2845-2856
Approximately 30 members of the tumor necrosis factor receptor superfamily (TNFRSF) have been identified. They are transmembrane proteins with cysteine‐rich motifs in their extracellular domains that bind to their cognate ligands 1. They are catego
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2633f18bf7a4d03a97ca8a72268db043
https://doi.org/10.1002/art.39816
https://doi.org/10.1002/art.39816