Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Edward Cherok"'
Autor:
J Anthony Graves, Yudong Wang, Sunder Sims-Lucas, Edward Cherok, Kristi Rothermund, Maria F Branca, Jennifer Elster, Donna Beer-Stolz, Bennett Van Houten, Jerry Vockley, Edward V Prochownik
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37699 (2012)
Although the c-Myc (Myc) oncoprotein controls mitochondrial biogenesis and multiple enzymes involved in oxidative phosphorylation (OXPHOS), the coordination of these events and the mechanistic underpinnings of their regulation remain largely unexplor
Externí odkaz:
https://doaj.org/article/0d1be3b02bfb4271b501c310e31c86fc
Autor:
Brian A. Roelofs, T. Chase Francis, Sruti Uppuluri, Mariusz Karbowski, Kie Itoh, Brian M. Polster, Ahmed Khalil, Andrew J. Saladino, Nolan W. Kennedy, Pascaline Clerc, Hiromi Sesaki, Laszlo Tretter, R. Blake Hill, Vera Adam-Vizi, Alexandrea M. Miller, Edward Cherok, Lora K. Picton, Shealinna X. Ge, Tanya Kumar, Evan A. Bordt, Nagendra Yadava
Mitochondrial fission mediated by the GTPase dynamin-related protein 1 (Drp1) is an attractive drug target in numerous maladies that range from heart disease to neurodegenerative disorders. The compound mdivi-1 is widely reported to inhibit Drp1-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afd387d613c5543232d146dfcbe8b65
https://europepmc.org/articles/PMC5398851/
https://europepmc.org/articles/PMC5398851/
Autor:
Michal Zalzman, Shweta Das, Edward Cherok, Chunxin Wang, Sunan Li, Mariusz Karbowski, W. Alex Meltzer, Shan Xu
Publikováno v:
Molecular Biology of the Cell
In addition to their direct roles in mitochondrial fission, Mff and Drp1 act as regulatory factors and control mitochondrial fission and fusion through a Ub-dependent mechanism. The E3 Ub ligase MARCH5 is negatively controlled by Mff and Drp1.
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Autor:
Karen K. Takane, Ronnie Troxell, Fatimah G. Salim, Nathalie Fiaschi-Taesch, Edward Cherok, Donald K. Scott, Andrew F. Stewart, Jeffrey W. Kleinberger, Karen Selk, Irene Cózar-Castellano
Publikováno v:
Diabetes
OBJECTIVE Most knowledge on human β-cell cycle control derives from immunoblots of whole human islets, mixtures of β-cells and non-β-cells. We explored the presence, subcellular localization, and function of five early G1/S phase molecules—cycli
Autor:
Luke Churley, Manika Sharma, Donna B. Stolz, Yudong Wang, Samantha Kelly, Sunder Sims-Lucas, J. Anthony Graves, Ming Sun, Lia R. Edmunds, Maria F. Branca, Jeff LaRosa, Gabriella P. Casinelli, Edward Cherok, Swati Banerjee
Publikováno v:
Cell Death Discovery
N-Myc is a global transcription factor that regulates the expression of genes involved in a number of essential cellular processes including: ribosome biogenesis, cell cycle and apoptosis. Upon deregulation, N-Myc can drive pathologic expression of m
Autor:
J. Anthony Graves, Edward Cherok
Publikováno v:
Cancer Research. 72:1114-1114
c-Myc (Myc) is a transcription factor that controls the expression of a vast array of genes that function in many essential cellular pathways, and high levels of Myc have been implicated in the development of many human cancers. One pathway that Myc